{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Pulmonary+Vein+Isolation",
    "query": {
      "intervention": "Pulmonary Vein Isolation"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 138,
    "total_pages": 14,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Pulmonary+Vein+Isolation&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-04T16:34:36.526Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02918396",
      "title": "The Substrate and Intervention Mechanisms for Persistent Atrial Fibrillation Trial",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Persistent Atrial Fibrillation"
      ],
      "interventions": [
        {
          "name": "Scar-Based Radio-frequency Ablation",
          "type": "DEVICE"
        },
        {
          "name": "Rotor Anchors Radio-frequency Ablation",
          "type": "DEVICE"
        },
        {
          "name": "Conventional PVI by Radio-frequency Ablation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 5,
      "start_date": "2016-04",
      "completion_date": "2017-10",
      "has_results": true,
      "last_update_posted_date": "2018-01-04",
      "last_synced_at": "2026-09-04T16:34:36.526Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02918396"
    },
    {
      "nct_id": "NCT01173796",
      "title": "Ablation of Perimitral Flutter Following Catheter Ablation of Atrial Fibrillation: Impact on Outcomes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Atrial Fibrillation",
        "Perimitral Flutter"
      ],
      "interventions": [
        {
          "name": "catheter ablation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Texas Cardiac Arrhythmia Research Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 44,
      "start_date": "2010-03",
      "completion_date": "2011-09",
      "has_results": false,
      "last_update_posted_date": "2012-07-11",
      "last_synced_at": "2026-09-04T16:34:36.526Z",
      "location_count": 1,
      "location_summary": "Austin, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01173796"
    },
    {
      "nct_id": "NCT00392054",
      "title": "First Line Radiofrequency Ablation Versus Antiarrhythmic Drugs for Atrial Fibrillation Treatment (The RAAFT Study)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Atrial Fibrillation"
      ],
      "interventions": [
        {
          "name": "Pulmonary Vein Isolation performed by Catheter Ablation",
          "type": "PROCEDURE"
        },
        {
          "name": "Conventional Antiarrhythmic Drug Therapy",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "Population Health Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "19 Years to 75 Years"
      },
      "enrollment_count": 127,
      "start_date": "2006-08",
      "completion_date": "2012-02",
      "has_results": true,
      "last_update_posted_date": "2020-01-31",
      "last_synced_at": "2026-09-04T16:34:36.526Z",
      "location_count": 2,
      "location_summary": "Austin, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        },
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00392054"
    },
    {
      "nct_id": "NCT04160000",
      "title": "Treatment Of Atrial Fibrillation In Preserved Cardiac Function Heart Failure",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Atrial Fibrillation",
        "Heart Failure",
        "Diastolic Heart Failure"
      ],
      "interventions": [
        {
          "name": "Catheter ablation",
          "type": "DEVICE"
        },
        {
          "name": "Rate or Rhythm control antiarrhythmic drugs for atrial fibrillation",
          "type": "DRUG"
        },
        {
          "name": "Insertion of CardioMems Hemodynamic monitor",
          "type": "DEVICE"
        },
        {
          "name": "Empiric heart failure drug therapy",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Electrophysiology Research Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 360,
      "start_date": "2020-07-26",
      "completion_date": "2025-06-30",
      "has_results": false,
      "last_update_posted_date": "2024-05-23",
      "last_synced_at": "2026-09-04T16:34:36.526Z",
      "location_count": 7,
      "location_summary": "Flagstaff, Arizona • Jonesboro, Arkansas • Littleton, Colorado + 4 more",
      "locations": [
        {
          "city": "Flagstaff",
          "state": "Arizona"
        },
        {
          "city": "Jonesboro",
          "state": "Arkansas"
        },
        {
          "city": "Littleton",
          "state": "Colorado"
        },
        {
          "city": "Overland",
          "state": "Missouri"
        },
        {
          "city": "Warren Township",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04160000"
    },
    {
      "nct_id": "NCT04505163",
      "title": "Left Atrial Posterior Wall and PV Isolation Using Cryoballoon for Treatment of Persistent AF",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Persistent Atrial Fibrillation"
      ],
      "interventions": [
        {
          "name": "Standard Cryoballoon Pulmonary Vein Isolation (PVI)",
          "type": "PROCEDURE"
        },
        {
          "name": "Cryoballoon PVI + Posterior Wall Isolation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "Dignity Health Medical Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 153,
      "start_date": "2021-04-30",
      "completion_date": "2024-12-31",
      "has_results": false,
      "last_update_posted_date": "2023-09-06",
      "last_synced_at": "2026-09-04T16:34:36.526Z",
      "location_count": 11,
      "location_summary": "Sacramento, California • Fort Collins, Colorado • Washington D.C., District of Columbia + 7 more",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Fort Collins",
          "state": "Colorado"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Sarasota",
          "state": "Florida"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04505163"
    },
    {
      "nct_id": "NCT03624881",
      "title": "Evaluation of VISITAG SURPOINT™ Module With External Processing Unit (EPU)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Paroxysmal Atrial Fibrillation"
      ],
      "interventions": [
        {
          "name": "Catheter ablation with EPU",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Biosense Webster, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 333,
      "start_date": "2018-09-04",
      "completion_date": "2021-06-28",
      "has_results": true,
      "last_update_posted_date": "2023-07-03",
      "last_synced_at": "2026-09-04T16:34:36.526Z",
      "location_count": 41,
      "location_summary": "Birmingham, Alabama • Huntsville, Alabama • Little Rock, Arkansas + 34 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Huntsville",
          "state": "Alabama"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03624881"
    },
    {
      "nct_id": "NCT01660100",
      "title": "Outcome of Atrial Fibrillation Ablation After Permanent Pulmonary Vein Antrum Isolation With or Without Proven Left Atrial Posterior Wall Isolation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Atrial Fibrillation"
      ],
      "interventions": [
        {
          "name": "Pulmonary vein antrum isolation (PVAI)",
          "type": "PROCEDURE"
        },
        {
          "name": "PVAI plus left atrial posterior wall (LAPW) isolation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Texas Cardiac Arrhythmia Research Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 400,
      "start_date": "2012-07",
      "completion_date": "2016-12",
      "has_results": false,
      "last_update_posted_date": "2017-10-19",
      "last_synced_at": "2026-09-04T16:34:36.526Z",
      "location_count": 1,
      "location_summary": "Austin, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01660100"
    },
    {
      "nct_id": "NCT03811795",
      "title": "Cryoballoon vs. Rhythmia Guided Ablation for Recurrent AFib",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Atrial Fibrillation"
      ],
      "interventions": [
        {
          "name": "ECG monitoring with a Kardia Mobile monitor",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Valley Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 9,
      "start_date": "2018-11-27",
      "completion_date": "2022-04-26",
      "has_results": false,
      "last_update_posted_date": "2026-06-24",
      "last_synced_at": "2026-09-04T16:34:36.526Z",
      "location_count": 3,
      "location_summary": "West Des Moines, Iowa • Paramus, New Jersey • Springfield, Oregon",
      "locations": [
        {
          "city": "West Des Moines",
          "state": "Iowa"
        },
        {
          "city": "Paramus",
          "state": "New Jersey"
        },
        {
          "city": "Springfield",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03811795"
    },
    {
      "nct_id": "NCT01034852",
      "title": "Efficacy Study for Surgery After Previous Failed Catheter Ablation",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Atrial Fibrillation Ablation"
      ],
      "interventions": [
        {
          "name": "Totally Thoracoscopic Maze",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Cardiopulmonary Research Science and Technology Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 45,
      "start_date": "2009-05",
      "completion_date": "2011-01",
      "has_results": false,
      "last_update_posted_date": "2012-02-22",
      "last_synced_at": "2026-09-04T16:34:36.526Z",
      "location_count": 2,
      "location_summary": "Springfield, Oregon • Dallas, Texas",
      "locations": [
        {
          "city": "Springfield",
          "state": "Oregon"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01034852"
    },
    {
      "nct_id": "NCT00434694",
      "title": "A Study of Strategies for Electrical Isolation of Pulmonic Veins for Curative Treatment of Atrial Fibrillation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Atrial Fibrillation"
      ],
      "interventions": [
        {
          "name": "Pulmonary Vein Isolation (Radiofrequency Catheter Ablation)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2003-07",
      "completion_date": "2006-02",
      "has_results": false,
      "last_update_posted_date": "2015-11-25",
      "last_synced_at": "2026-09-04T16:34:36.526Z",
      "location_count": 2,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00434694"
    }
  ]
}