{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Pulsatile+blood+flow",
    "query": {
      "intervention": "Pulsatile blood flow"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-17T06:01:49.993Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02812225",
      "title": "Non-blinded Data Collection Study of Concussion Using the BrainPulse(TM)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Brain Concussion",
        "Mild Traumatic Brain Injury"
      ],
      "interventions": [
        {
          "name": "BrainPulse",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Jan Medical, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "5 Years and older"
      },
      "enrollment_count": 406,
      "start_date": "2016-06",
      "completion_date": "2019-01",
      "has_results": false,
      "last_update_posted_date": "2022-06-09",
      "last_synced_at": "2026-09-17T06:01:49.993Z",
      "location_count": 3,
      "location_summary": "Boston, Massachusetts • Cincinnati, Ohio • Johnson City, Tennessee",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        },
        {
          "city": "Johnson City",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02812225"
    },
    {
      "nct_id": "NCT01976728",
      "title": "LutrePulse Hypogonadotropic Hypogonadism",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Primary Amenorrhea With Hypogonadotropic Hypogonadism"
      ],
      "interventions": [
        {
          "name": "Gonadorelin acetate subcutaneous (SC) 10 μg/pulse as a fixed dose, administered via. OmniPod pump",
          "type": "DRUG"
        },
        {
          "name": "Gonadorelin acetate SC 15 μg/pulse as a fixed dose, administered via. OmniPod pump",
          "type": "DRUG"
        },
        {
          "name": "Gonadorelin acetate SC 20 μg/pulse as a fixed dose, administered via. OmniPod pump",
          "type": "DRUG"
        },
        {
          "name": "Placebo (SC 10, 15, or 20 μg/pulse as a fixed dose, administered via. OmniPod pump)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Ferring Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 40 Years · Female only"
      },
      "enrollment_count": 39,
      "start_date": "2014-04-01",
      "completion_date": "2018-02-23",
      "has_results": true,
      "last_update_posted_date": "2021-03-03",
      "last_synced_at": "2026-09-17T06:01:49.993Z",
      "location_count": 33,
      "location_summary": "Tempe, Arizona • San Francisco, California • Aurora, Colorado + 28 more",
      "locations": [
        {
          "city": "Tempe",
          "state": "Arizona"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Newark",
          "state": "Delaware"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01976728"
    },
    {
      "nct_id": "NCT04526249",
      "title": "Evaluation of Efficacy of the Prototype RPC (Rapid Pulse Confirmation) Device in Detecting Return of Pulsatile Flow in Patients Preparing to Separate From CPB (Cardiopulmonary Bypass)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Circulatory Failure",
        "Cardiac Arrest"
      ],
      "interventions": [
        {
          "name": "rapid pulse confirmation device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Michael Kyle Ritchie",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 10,
      "start_date": "2017-10-17",
      "completion_date": "2019-01-20",
      "has_results": false,
      "last_update_posted_date": "2020-08-25",
      "last_synced_at": "2026-09-17T06:01:49.993Z",
      "location_count": 1,
      "location_summary": "Morgantown, West Virginia",
      "locations": [
        {
          "city": "Morgantown",
          "state": "West Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04526249"
    },
    {
      "nct_id": "NCT01550315",
      "title": "Effect of Dietary Sodium Intake on Vascular Endothelium",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Postural Tachycardia Syndrome (POTS)"
      ],
      "interventions": [
        {
          "name": "Pulsitile Arterial Tonometry (PAT) Protocol",
          "type": "PROCEDURE"
        },
        {
          "name": "Calf Blood Flow in Reactive Hyperemia (CBF-RH)",
          "type": "DEVICE"
        },
        {
          "name": "Evaluation of Forearm-Mediated Dilation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 27,
      "start_date": "2012-04",
      "completion_date": "2021-09",
      "has_results": true,
      "last_update_posted_date": "2022-01-05",
      "last_synced_at": "2026-09-17T06:01:49.993Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01550315"
    },
    {
      "nct_id": "NCT02992795",
      "title": "Unblinded Data Collection Study of Concussion Using BrainPulse",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Concussion, Intermediate"
      ],
      "interventions": [
        {
          "name": "BrainPulse",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Jan Medical, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "28 Years",
        "sex": "ALL",
        "summary": "18 Years to 28 Years"
      },
      "enrollment_count": 353,
      "start_date": "2016-11",
      "completion_date": "2017-08",
      "has_results": false,
      "last_update_posted_date": "2018-09-20",
      "last_synced_at": "2026-09-17T06:01:49.993Z",
      "location_count": 1,
      "location_summary": "Laramie, Wyoming",
      "locations": [
        {
          "city": "Laramie",
          "state": "Wyoming"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02992795"
    },
    {
      "nct_id": "NCT05983744",
      "title": "Pulsatile Perfusion Therapy Phase II",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hemorrhage"
      ],
      "interventions": [
        {
          "name": "0 Hz Control",
          "type": "OTHER"
        },
        {
          "name": "0.1 Hz PPT",
          "type": "OTHER"
        },
        {
          "name": "0.05 Hz PPT",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Caroline Rickards",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 21,
      "start_date": "2020-02-27",
      "completion_date": "2021-12-17",
      "has_results": false,
      "last_update_posted_date": "2023-08-09",
      "last_synced_at": "2026-09-17T06:01:49.993Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05983744"
    },
    {
      "nct_id": "NCT03235271",
      "title": "Pilot Study of Acute Stroke Using the Brainpulse™",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Stroke, Acute"
      ],
      "interventions": [
        {
          "name": "BrainPulse Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Jan Medical, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 252,
      "start_date": "2017-09-10",
      "completion_date": "2024-08-28",
      "has_results": false,
      "last_update_posted_date": "2025-03-07",
      "last_synced_at": "2026-09-17T06:01:49.993Z",
      "location_count": 3,
      "location_summary": "Arlington Heights, Illinois • Evanston, Illinois • Cincinnati, Ohio",
      "locations": [
        {
          "city": "Arlington Heights",
          "state": "Illinois"
        },
        {
          "city": "Evanston",
          "state": "Illinois"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03235271"
    },
    {
      "nct_id": "NCT03908879",
      "title": "Intraosseous Catheter Confirmation Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Critical Illness"
      ],
      "interventions": [
        {
          "name": "Standard intraosseous (IO) catheter confirmation procedure",
          "type": "PROCEDURE"
        },
        {
          "name": "Color flow Doppler intraosseous (IO) catheter confirmation procedure",
          "type": "PROCEDURE"
        },
        {
          "name": "Pressure transduction intraosseous (IO) catheter confirmation procedure",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Rutgers, The State University of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 34,
      "start_date": "2019-07-23",
      "completion_date": "2022-05-01",
      "has_results": false,
      "last_update_posted_date": "2023-09-08",
      "last_synced_at": "2026-09-17T06:01:49.993Z",
      "location_count": 1,
      "location_summary": "Newark, New Jersey",
      "locations": [
        {
          "city": "Newark",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03908879"
    },
    {
      "nct_id": "NCT00733447",
      "title": "SynCardia Freedom Driver System Study",
      "overall_status": "APPROVED_FOR_MARKETING",
      "study_type": "EXPANDED_ACCESS",
      "phases": [],
      "conditions": [
        "Biventricular Failure"
      ],
      "interventions": [
        {
          "name": "CardioWest temporary Total Artificial Heart (TAH-t) System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "SynCardia Systems. LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": null,
      "start_date": "2010-03",
      "completion_date": "2014-05",
      "has_results": false,
      "last_update_posted_date": "2015-07-30",
      "last_synced_at": "2026-09-17T06:01:49.993Z",
      "location_count": 3,
      "location_summary": "Phoenix, Arizona • Philadelphia, Pennsylvania • Richmond, Virginia",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00733447"
    },
    {
      "nct_id": "NCT06349577",
      "title": "Optimizing Pulsatility During Cardiopulmonary Bypass to Reduce Acute Kidney Injury",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Kidney Injury",
        "Hemolysis",
        "Thrombocytopenia",
        "Surgery"
      ],
      "interventions": [
        {
          "name": "Non-pulsatile blood flow",
          "type": "OTHER"
        },
        {
          "name": "Pulsatile blood flow",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 1100,
      "start_date": "2025-05-19",
      "completion_date": "2028-10",
      "has_results": false,
      "last_update_posted_date": "2025-05-21",
      "last_synced_at": "2026-09-17T06:01:49.993Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06349577"
    }
  ]
}