{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Pyridoxine+hydrochloride", "query": { "intervention": "Pyridoxine hydrochloride" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 52, "total_pages": 6, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Pyridoxine+hydrochloride&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-10-02T04:12:32.571Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00004734", "title": "Vitamin Therapy for Prevention of Stroke", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Stroke", "Cerebral Infarction", "Myocardial Infarction" ], "interventions": [ { "name": "pyridoxine", "type": "DRUG" }, { "name": "cyanocobalamin", "type": "DRUG" }, { "name": "folic acid multivitamin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Neurological Disorders and Stroke (NINDS)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "35 Years", "maximum_age": null, "sex": "ALL", "summary": "35 Years and older" }, "enrollment_count": null, "start_date": "1996-09", "completion_date": "2004-02", "has_results": false, "last_update_posted_date": "2005-06-24", "last_synced_at": "2026-10-02T04:12:32.571Z", "location_count": 1, "location_summary": "Winston-Salem, North Carolina", "locations": [ { "city": "Winston-Salem", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00004734" }, { "nct_id": "NCT02589145", "title": "Lenalidomide Combined With Vorinostat/Gemcitabine/Busulfan/Melphalan With Autologous Stem-Cell Transplantation in Diffuse Large B-Cell Lymphoma of the ABC Subtype", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Lymphoma" ], "interventions": [ { "name": "Lenalidomide", "type": "DRUG" }, { "name": "Vorinostat", "type": "DRUG" }, { "name": "Gemcitabine", "type": "DRUG" }, { "name": "Busulfan", "type": "DRUG" }, { "name": "Melphalan", "type": "DRUG" }, { "name": "Rituximab", "type": "DRUG" }, { "name": "Dexamethasone", "type": "DRUG" }, { "name": "Caphosol", "type": "DRUG" }, { "name": "Glutamine", "type": "DRUG" }, { "name": "Pyridoxine", "type": "DRUG" }, { "name": "Enoxaparin", "type": "DRUG" }, { "name": "Stem Cell Transplant", "type": "PROCEDURE" }, { "name": "Palifermin", "type": "DRUG" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "M.D. Anderson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "15 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "15 Years to 65 Years" }, "enrollment_count": 8, "start_date": "2016-06-22", "completion_date": "2019-04-08", "has_results": true, "last_update_posted_date": "2019-12-13", "last_synced_at": "2026-10-02T04:12:32.571Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02589145" }, { "nct_id": "NCT03783728", "title": "Video Based Directly Observed Therapy for Latent TB", "overall_status": "WITHDRAWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Latent Tuberculosis" ], "interventions": [ { "name": "Rifapentine 600 mg orally", "type": "DRUG" }, { "name": "Isoniazid 900 mg orally", "type": "DRUG" }, { "name": "Pyridoxine 50 mg orally", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "St. Louis University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 0, "start_date": "2019-06-30", "completion_date": "2020-01-31", "has_results": false, "last_update_posted_date": "2019-07-01", "last_synced_at": "2026-10-02T04:12:32.571Z", "location_count": 1, "location_summary": "St Louis, Missouri", "locations": [ { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT03783728" }, { "nct_id": "NCT01404312", "title": "Brief Rifapentine-Isoniazid Evaluation for TB Prevention (BRIEF TB)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Tuberculosis", "HIV Infections" ], "interventions": [ { "name": "Rifapentine (RPT)", "type": "DRUG" }, { "name": "Isoniazid (INH)", "type": "DRUG" }, { "name": "Pyridoxine (Vitamin B6)", "type": "DIETARY_SUPPLEMENT" } ], "intervention_types": [ "DRUG", "DIETARY_SUPPLEMENT" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "13 Years", "maximum_age": null, "sex": "ALL", "summary": "13 Years and older" }, "enrollment_count": 3000, "start_date": "2012-05-23", "completion_date": "2017-11-14", "has_results": true, "last_update_posted_date": "2021-11-04", "last_synced_at": "2026-10-02T04:12:32.571Z", "location_count": 21, "location_summary": "La Jolla, California • Los Angeles, California • San Diego, California + 17 more", "locations": [ { "city": "La Jolla", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Torrance", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01404312" }, { "nct_id": "NCT00000636", "title": "Prophylaxis Against Tuberculosis (TB) in Patients With Human Immunodeficiency Virus (HIV) Infection and Confirmed Latent Tuberculous Infection", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "HIV Infections", "Tuberculosis" ], "interventions": [ { "name": "Isoniazid", "type": "DRUG" }, { "name": "Pyrazinamide", "type": "DRUG" }, { "name": "Pyridoxine hydrochloride", "type": "DRUG" }, { "name": "Rifampin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "13 Years", "maximum_age": null, "sex": "ALL", "summary": "13 Years and older" }, "enrollment_count": 2000, "start_date": null, "completion_date": "1997-10", "has_results": false, "last_update_posted_date": "2021-11-02", "last_synced_at": "2026-10-02T04:12:32.571Z", "location_count": 25, "location_summary": "San Francisco, California • Denver, Colorado • New Haven, Connecticut + 15 more", "locations": [ { "city": "San Francisco", "state": "California" }, { "city": "Denver", "state": "Colorado" }, { "city": "New Haven", "state": "Connecticut" }, { "city": "Wilmington", "state": "Delaware" }, { "city": "Washington D.C.", "state": "District of Columbia" } ], "official_url": "https://clinicaltrials.gov/study/NCT00000636" }, { "nct_id": "NCT00245050", "title": "Pyridoxine in Preventing Hand-Foot Syndrome in Patients Who Are Receiving Liposomal Doxorubicin for Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Breast Cancer", "Drug/Agent Toxicity by Tissue/Organ", "Endometrial Cancer", "Fallopian Tube Cancer", "Ovarian Cancer", "Peritoneal Cavity Cancer" ], "interventions": [ { "name": "pyridoxine hydrochloride", "type": "DIETARY_SUPPLEMENT" }, { "name": "Placebo", "type": "DRUG" }, { "name": "doxorubicin HCL liposome", "type": "DRUG" } ], "intervention_types": [ "DIETARY_SUPPLEMENT", "DRUG" ], "sponsor": "Case Comprehensive Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "FEMALE", "summary": "Female only" }, "enrollment_count": 34, "start_date": "2004-04", "completion_date": "2011-09", "has_results": true, "last_update_posted_date": "2011-12-30", "last_synced_at": "2026-10-02T04:12:32.571Z", "location_count": 8, "location_summary": "Cleveland, Ohio", "locations": [ { "city": "Cleveland", "state": "Ohio" }, { "city": "Cleveland", "state": "Ohio" }, { "city": "Cleveland", "state": "Ohio" }, { "city": "Cleveland", "state": "Ohio" }, { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT00245050" }, { "nct_id": "NCT00000778", "title": "A Pilot Study of Methodology to Rapidly Evaluate Drugs for Bactericidal Activity, Tolerance, and Pharmacokinetics in the Treatment of Pulmonary Tuberculosis Using Isoniazid and Levofloxacin", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "HIV Infections", "Tuberculosis" ], "interventions": [ { "name": "Isoniazid", "type": "DRUG" }, { "name": "Pyridoxine hydrochloride", "type": "DRUG" }, { "name": "Levofloxacin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 44, "start_date": null, "completion_date": null, "has_results": false, "last_update_posted_date": "2008-08-08", "last_synced_at": "2026-10-02T04:12:32.571Z", "location_count": 10, "location_summary": "Birmingham, Alabama • Los Angeles, California • Torrance, California + 7 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Los Angeles", "state": "California" }, { "city": "Torrance", "state": "California" }, { "city": "Fort Lauderdale", "state": "Florida" }, { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00000778" }, { "nct_id": "NCT02045901", "title": "A Multicenter Trial of the Efficacy and Safety of Diclegis® for Nausea and Vomiting of Pregnancy in Pregnant Adolescents", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Morning Sickness" ], "interventions": [ { "name": "Diclegis", "type": "DRUG" }, { "name": "Placebo (Sugar Pill)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Duchesnay Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "12 Years", "maximum_age": "17 Years", "sex": "FEMALE", "summary": "12 Years to 17 Years · Female only" }, "enrollment_count": 131, "start_date": "2014-02", "completion_date": "2017-10", "has_results": false, "last_update_posted_date": "2021-11-23", "last_synced_at": "2026-10-02T04:12:32.571Z", "location_count": 8, "location_summary": "Tucson, Arizona • Los Angeles, California • Norwalk, California + 5 more", "locations": [ { "city": "Tucson", "state": "Arizona" }, { "city": "Los Angeles", "state": "California" }, { "city": "Norwalk", "state": "California" }, { "city": "Miami", "state": "Florida" }, { "city": "Miami Lakes", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT02045901" }, { "nct_id": "NCT05411744", "title": "One-month Latent Tuberculosis Treatment for Renal Transplant Candidates", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Latent Tuberculosis", "End Stage Renal Disease", "Renal Transplant Candidate for Right Kidney", "Renal Transplant Candidate for Left Kidney" ], "interventions": [ { "name": "1 month Rifapentine, Isoniazid and Vitamin B6", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Rutgers, The State University of New Jersey", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "18 Years to 90 Years" }, "enrollment_count": 25, "start_date": "2022-07-01", "completion_date": "2029-06-30", "has_results": false, "last_update_posted_date": "2026-01-21", "last_synced_at": "2026-10-02T04:12:32.571Z", "location_count": 1, "location_summary": "New Brunswick, New Jersey", "locations": [ { "city": "New Brunswick", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT05411744" }, { "nct_id": "NCT06023082", "title": "A Single-Group Study to Examine the Efficacy of a Gut Health Supplement to Increase Metabolism, Improve Gut Health, and Support Weight Management", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Gut Health", "Metabolism", "Weight Loss", "Energy" ], "interventions": [ { "name": "Colon Broom Premium supplement", "type": "DIETARY_SUPPLEMENT" } ], "intervention_types": [ "DIETARY_SUPPLEMENT" ], "sponsor": "Gut Health, UAB", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "30 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "30 Years to 50 Years" }, "enrollment_count": 120, "start_date": "2023-07-26", "completion_date": "2023-11-26", "has_results": true, "last_update_posted_date": "2025-01-13", "last_synced_at": "2026-10-02T04:12:32.571Z", "location_count": 1, "location_summary": "Santa Monica, California", "locations": [ { "city": "Santa Monica", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06023082" } ] }