{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=QuantumLeap",
    "query": {
      "intervention": "QuantumLeap"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 2,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-06T07:34:06.538Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05868226",
      "title": "PRE-ISPY Phase I/II Oncology Platform Program",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "HER2-positive Breast Cancer",
        "Metastatic Cancer",
        "Metastatic Breast Cancer",
        "Metastatic",
        "HER2-positive Metastatic Breast Cancer",
        "HER2 Mutation-Related Tumors",
        "HER-2 Protein Overexpression",
        "HER2-negative Breast Cancer",
        "Triple Negative Breast Cancer",
        "HR Positive",
        "Hormone Receptor-positive Breast Cancer",
        "Estrogen Receptor Positive Tumor",
        "Progesterone Receptor-positive Breast Cancer",
        "Hormone Receptor Negative Breast Carcinoma",
        "Solid Tumor",
        "Solid Tumor, Adult",
        "Solid Carcinoma",
        "HER2 Low Breast Cancer",
        "HER2 Low Breast Carcinoma",
        "ER Positive Breast Cancer",
        "PR-positive Breast Cancer",
        "Minimal Residual Disease",
        "Colo-rectal Cancer",
        "Colon Cancer",
        "Rectal Cancer",
        "ctDNA Monitoring",
        "Colorectal Neoplasms",
        "Colonic Neoplasms",
        "Rectal Neoplasms",
        "Neoplasm, Residual",
        "Adenocarcinoma of Colon",
        "Adenocarcinoma"
      ],
      "interventions": [
        {
          "name": "ALX148",
          "type": "DRUG"
        },
        {
          "name": "Fam-Trastuzumab Deruxtecan-Nxki",
          "type": "DRUG"
        },
        {
          "name": "Zanidatamab",
          "type": "DRUG"
        },
        {
          "name": "Tucatinib",
          "type": "DRUG"
        },
        {
          "name": "TTX-MC138",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "QuantumLeap Healthcare Collaborative",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 280,
      "start_date": "2023-02-15",
      "completion_date": "2031-12-30",
      "has_results": false,
      "last_update_posted_date": "2026-09-02",
      "last_synced_at": "2026-09-06T07:34:06.538Z",
      "location_count": 10,
      "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Aurora, Colorado + 7 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05868226"
    },
    {
      "nct_id": "NCT02772276",
      "title": "Pharmacokinetics of MB-102 and Use of the Non-invasive Optical Renal Function Monitor (ORFM) Device in Subjects With Normal and Impaired Renal Function and a Range of Skin Color Types",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Acute Kidney Injury"
      ],
      "interventions": [
        {
          "name": "MB-102-- single dose of 4 µmol/kg",
          "type": "DRUG"
        },
        {
          "name": "MB-102-- single dose of 130 mg",
          "type": "DRUG"
        },
        {
          "name": "MB-102-single dose of 130 mg or 2 doses of 130 mg 12 hours apart",
          "type": "DRUG"
        },
        {
          "name": "MB-102-- two doses of 130 mg 24 hours apart",
          "type": "DRUG"
        },
        {
          "name": "Iohexol",
          "type": "DRUG"
        },
        {
          "name": "QuantumLeap",
          "type": "DEVICE"
        },
        {
          "name": "Radiance",
          "type": "DEVICE"
        },
        {
          "name": "Brilliance (1 or 2 sensors)",
          "type": "DEVICE"
        },
        {
          "name": "Brilliance (2-part sensor)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "MediBeacon",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 234,
      "start_date": "2016-05-11",
      "completion_date": "2021-08-04",
      "has_results": true,
      "last_update_posted_date": "2023-10-26",
      "last_synced_at": "2026-09-06T07:34:06.538Z",
      "location_count": 3,
      "location_summary": "Edgewater, Florida • Orlando, Florida • St Louis, Missouri",
      "locations": [
        {
          "city": "Edgewater",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02772276"
    }
  ]
}