{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=RF+Non-Invasive+Treatment",
    "query": {
      "intervention": "RF Non-Invasive Treatment"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 22,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=RF+Non-Invasive+Treatment&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-06T14:12:43.193Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01859611",
      "title": "TriActive+ Radiofrequency (RF) for Non-Invasive Treatment of Wrinkles and Rhytides",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Wrinkles",
        "Rhytides"
      ],
      "interventions": [
        {
          "name": "TriActive+ RF",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "El. En. SpA",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "30 Years to 60 Years"
      },
      "enrollment_count": 51,
      "start_date": "2013-05",
      "completion_date": "2014-05",
      "has_results": true,
      "last_update_posted_date": "2015-04-07",
      "last_synced_at": "2026-09-06T14:12:43.193Z",
      "location_count": 2,
      "location_summary": "Indianapolis, Indiana • New York, New York",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01859611"
    },
    {
      "nct_id": "NCT03756168",
      "title": "Clinical Evaluation of the Safety and Efficacy of a 1060 nm Diode Laser (Flanks)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fat Atrophy"
      ],
      "interventions": [
        {
          "name": "1060nm Diode laser",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Venus Concept",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2018-11-14",
      "completion_date": "2019-07-02",
      "has_results": true,
      "last_update_posted_date": "2024-01-30",
      "last_synced_at": "2026-09-06T14:12:43.193Z",
      "location_count": 2,
      "location_summary": "Sacramento, California • Dallas, Texas",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03756168"
    },
    {
      "nct_id": "NCT04881058",
      "title": "Post Market Clinical Follow Up Study to Collect Additional Data and Imaging",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pigmentation",
        "Wrinkle"
      ],
      "interventions": [
        {
          "name": "RF Non-Invasive Treatment",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Cynosure, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 10,
      "start_date": "2021-04-27",
      "completion_date": "2022-03-11",
      "has_results": true,
      "last_update_posted_date": "2023-06-27",
      "last_synced_at": "2026-09-06T14:12:43.193Z",
      "location_count": 1,
      "location_summary": "Montclair, New Jersey",
      "locations": [
        {
          "city": "Montclair",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04881058"
    },
    {
      "nct_id": "NCT01480167",
      "title": "The PRIORi-T Trial--Prospective Randomized Investigation of Radiofrequency Targeted Vertebral Augmentation",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Painful Osteoporotic Vertebral Compression Fractures (VCF)"
      ],
      "interventions": [
        {
          "name": "Vertebral Augmentation (STABILIT)",
          "type": "DEVICE"
        },
        {
          "name": "Non-operative Management",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "DFINE Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "21 Years to 90 Years"
      },
      "enrollment_count": 0,
      "start_date": "2011-11",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2017-01-20",
      "last_synced_at": "2026-09-06T14:12:43.193Z",
      "location_count": 6,
      "location_summary": "St Louis, Missouri • Lebanon, New Hampshire • Mineola, New York + 3 more",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Lebanon",
          "state": "New Hampshire"
        },
        {
          "city": "Mineola",
          "state": "New York"
        },
        {
          "city": "The Bronx",
          "state": "New York"
        },
        {
          "city": "Hershey",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01480167"
    },
    {
      "nct_id": "NCT03831477",
      "title": "Clinical Evaluation of Fractional Radiofrequency for the Treatment and Reduction of Facial Wrinkles",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Rhytides",
        "Wrinkle"
      ],
      "interventions": [
        {
          "name": "Venus Viva",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Venus Concept",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 15,
      "start_date": "2018-12-12",
      "completion_date": "2019-08-09",
      "has_results": true,
      "last_update_posted_date": "2023-09-06",
      "last_synced_at": "2026-09-06T14:12:43.193Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03831477"
    },
    {
      "nct_id": "NCT04012814",
      "title": "Clinical Evaluation of a 1060 nm Diode Laser, PEMF and Vacuum Assisted MP RF for Non-invasive Fat Reduction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Adipose Tissue Atrophy"
      ],
      "interventions": [
        {
          "name": "Venus Bliss",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Venus Concept",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 39,
      "start_date": "2019-09-19",
      "completion_date": "2022-10-22",
      "has_results": true,
      "last_update_posted_date": "2024-04-23",
      "last_synced_at": "2026-09-06T14:12:43.193Z",
      "location_count": 5,
      "location_summary": "Los Altos, California • Sacramento, California • Santa Monica, California + 2 more",
      "locations": [
        {
          "city": "Los Altos",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Santa Monica",
          "state": "California"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04012814"
    },
    {
      "nct_id": "NCT04090853",
      "title": "Subject Evaluation of a 1064nm Diode Laser/RF",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Subcutaneous Fat Disorder"
      ],
      "interventions": [
        {
          "name": "Venus Bliss",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Venus Concept",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2019-10-01",
      "completion_date": "2020-07-08",
      "has_results": false,
      "last_update_posted_date": "2023-05-08",
      "last_synced_at": "2026-09-06T14:12:43.193Z",
      "location_count": 3,
      "location_summary": "Denver, Colorado • Foxborough, Massachusetts • Woodmere, New York",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Foxborough",
          "state": "Massachusetts"
        },
        {
          "city": "Woodmere",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04090853"
    },
    {
      "nct_id": "NCT04807179",
      "title": "Clinical Study to Evaluate Alexandrite Laser for the Treatment of Acne Scars",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acne Scars"
      ],
      "interventions": [
        {
          "name": "Experimental: RF Device Arm",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Cynosure, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 39,
      "start_date": "2021-03-08",
      "completion_date": "2024-08-02",
      "has_results": false,
      "last_update_posted_date": "2024-05-07",
      "last_synced_at": "2026-09-06T14:12:43.193Z",
      "location_count": 2,
      "location_summary": "Los Angeles, California • New York, New York",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04807179"
    },
    {
      "nct_id": "NCT05256771",
      "title": "Electrical Muscle Stimulation with 1064 Nm Diode Laser and RF/PEMF for Non-invasive Body Contouring and Fat Reduction.",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fat Reduction",
        "Muscle Tone Increased"
      ],
      "interventions": [
        {
          "name": "EMS",
          "type": "DEVICE"
        },
        {
          "name": "1064 nm diode laser",
          "type": "DEVICE"
        },
        {
          "name": "RF/PEMF",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Venus Concept",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 36,
      "start_date": "2021-11-01",
      "completion_date": "2025-09-30",
      "has_results": false,
      "last_update_posted_date": "2025-03-28",
      "last_synced_at": "2026-09-06T14:12:43.193Z",
      "location_count": 3,
      "location_summary": "San Diego, California • Hackensack, New Jersey • Nashville, Tennessee",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Hackensack",
          "state": "New Jersey"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05256771"
    },
    {
      "nct_id": "NCT01460927",
      "title": "TriActive+ Radiofrequency (RF) for Non-invasive Treatment of Wrinkles & Rhytides",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Wrinkles",
        "Rhytides"
      ],
      "interventions": [
        {
          "name": "TriActive+ RF",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Deka Medical, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "30 Years to 60 Years"
      },
      "enrollment_count": 25,
      "start_date": "2011-10",
      "completion_date": "2012-04",
      "has_results": true,
      "last_update_posted_date": "2014-07-04",
      "last_synced_at": "2026-09-06T14:12:43.193Z",
      "location_count": 1,
      "location_summary": "Vancouver, Washington",
      "locations": [
        {
          "city": "Vancouver",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01460927"
    }
  ]
}