{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Radiofrequency+denervation",
    "query": {
      "intervention": "Radiofrequency denervation"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 26,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Radiofrequency+denervation&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-21T04:12:23.749Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06880562",
      "title": "The RESPLASH Study",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Resistant Hypertension"
      ],
      "interventions": [
        {
          "name": "Splanchnic Nerve Denervation",
          "type": "DEVICE"
        },
        {
          "name": "Renal Denervation Only",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Tulane University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 20,
      "start_date": "2026-06",
      "completion_date": "2027-06",
      "has_results": false,
      "last_update_posted_date": "2026-03-03",
      "last_synced_at": "2026-09-21T04:12:23.749Z",
      "location_count": 1,
      "location_summary": "New Orleans, Louisiana",
      "locations": [
        {
          "city": "New Orleans",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06880562"
    },
    {
      "nct_id": "NCT00484159",
      "title": "Efficacy and Cost: Benefit Ratio of 0, 1, and 2 Medial Branch Blocks for Lumbar Facet Joint Radiofrequency Denervation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain"
      ],
      "interventions": [
        {
          "name": "Radiofrequency denervation of medial branches",
          "type": "PROCEDURE"
        },
        {
          "name": "0.5% bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "2% lidocaine",
          "type": "DRUG"
        },
        {
          "name": "Radiofrequency denervation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 151,
      "start_date": "2007-02",
      "completion_date": "2009-01",
      "has_results": true,
      "last_update_posted_date": "2011-07-26",
      "last_synced_at": "2026-09-21T04:12:23.749Z",
      "location_count": 2,
      "location_summary": "Washington D.C., District of Columbia • Baltimore, Maryland",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00484159"
    },
    {
      "nct_id": "NCT01635998",
      "title": "Adjunctive Renal Denervation in the Treatment of Atrial Fibrillation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Uncontrolled Hypertension",
        "Atrial Fibrillation"
      ],
      "interventions": [
        {
          "name": "Boston Scientific Vessix Renal Denervation System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Vivek Reddy",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 50,
      "start_date": "2012-09-17",
      "completion_date": "2019-07-11",
      "has_results": true,
      "last_update_posted_date": "2020-11-05",
      "last_synced_at": "2026-09-21T04:12:23.749Z",
      "location_count": 6,
      "location_summary": "Sacramento, California • Kansas City, Kansas • Boston, Massachusetts + 2 more",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Kansas City",
          "state": "Kansas"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01635998"
    },
    {
      "nct_id": "NCT04285554",
      "title": "Evaluation of the Integrated Radio Frequency Denervation System to Improve Glycemic Control in Type 2 Diabetic Subjects",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes Mellitus, Type 2"
      ],
      "interventions": [
        {
          "name": "iRF System Hepatic Denervation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Metavention",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "22 Years to 70 Years"
      },
      "enrollment_count": 15,
      "start_date": "2020-07-28",
      "completion_date": "2022-12-19",
      "has_results": false,
      "last_update_posted_date": "2023-03-15",
      "last_synced_at": "2026-09-21T04:12:23.749Z",
      "location_count": 8,
      "location_summary": "Birmingham, Alabama • Stanford, California • Orlando, Florida + 5 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Springfield",
          "state": "Illinois"
        },
        {
          "city": "Coon Rapids",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04285554"
    },
    {
      "nct_id": "NCT01897545",
      "title": "Combined Treatment of Arterial Hypertension and Atrial Fibrillation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Arterial Hypertension",
        "Atrial Fibrillation"
      ],
      "interventions": [
        {
          "name": "Circumferential PV isolation",
          "type": "PROCEDURE"
        },
        {
          "name": "PV isolation+renal denervation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Meshalkin Research Institute of Pathology of Circulation",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 60,
      "start_date": "2012-04",
      "completion_date": "2013-06",
      "has_results": false,
      "last_update_posted_date": "2013-10-09",
      "last_synced_at": "2026-09-21T04:12:23.749Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01897545"
    },
    {
      "nct_id": "NCT02345629",
      "title": "Cordotomy for Refractory Cancer Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Advanced Cancers",
        "Pain"
      ],
      "interventions": [
        {
          "name": "Cordotomy",
          "type": "PROCEDURE"
        },
        {
          "name": "Pain/Symptom Questionnaire",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sharpness Sensory Testing",
          "type": "PROCEDURE"
        },
        {
          "name": "Heat Pain Sensory Testing",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "BEHAVIORAL"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 18,
      "start_date": "2015-03-10",
      "completion_date": "2020-02-25",
      "has_results": false,
      "last_update_posted_date": "2023-06-07",
      "last_synced_at": "2026-09-21T04:12:23.749Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02345629"
    },
    {
      "nct_id": "NCT01747837",
      "title": "REnal SympathetiC Denervation to sUpprEss Tachyarrhythmias in ICD Recipients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ventricular Tachycardia"
      ],
      "interventions": [
        {
          "name": "Boston Scientific Vessix Renal Denervation System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Vivek Reddy",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 48,
      "start_date": "2015-10-22",
      "completion_date": "2019-01-09",
      "has_results": true,
      "last_update_posted_date": "2020-03-04",
      "last_synced_at": "2026-09-21T04:12:23.749Z",
      "location_count": 2,
      "location_summary": "New York, New York • Austin, Texas",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01747837"
    },
    {
      "nct_id": "NCT04182620",
      "title": "Ultrasound-Based Renal Sympathetic Denervation as Adjunctive Upstream Therapy During Atrial Fibrillation Ablation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Atrial Fibrillation"
      ],
      "interventions": [
        {
          "name": "renal denervation",
          "type": "DEVICE"
        },
        {
          "name": "Catheter ablation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Vivek Reddy",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 160,
      "start_date": "2020-07-08",
      "completion_date": "2025-02-26",
      "has_results": false,
      "last_update_posted_date": "2025-05-08",
      "last_synced_at": "2026-09-21T04:12:23.749Z",
      "location_count": 13,
      "location_summary": "Phoenix, Arizona • Jonesboro, Arkansas • Loma Linda, California + 9 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Jonesboro",
          "state": "Arkansas"
        },
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "Santa Monica",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04182620"
    },
    {
      "nct_id": "NCT00373724",
      "title": "A Placebo-Controlled Study Assessing Lateral Branch Radiofrequency Denervation for Sacroiliac (SI) Joint Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain"
      ],
      "interventions": [
        {
          "name": "radiofrequency denervation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2005-11",
      "completion_date": "2007-08",
      "has_results": false,
      "last_update_posted_date": "2008-05-09",
      "last_synced_at": "2026-09-21T04:12:23.749Z",
      "location_count": 2,
      "location_summary": "Washington D.C., District of Columbia • Baltimore, Maryland",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00373724"
    },
    {
      "nct_id": "NCT03631030",
      "title": "Cooled RF Lesion MRI Characteristics",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Arthritis;Lumbosacral",
        "Osteo Arthritis Knee",
        "Sacroiliitis",
        "Hip Osteoarthritis",
        "Arthritis, Degenerative"
      ],
      "interventions": [
        {
          "name": "Cooled radiofrequency ablation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "International Spine, Pain and Performance Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 15,
      "start_date": "2018-02-25",
      "completion_date": "2020-01",
      "has_results": false,
      "last_update_posted_date": "2019-08-07",
      "last_synced_at": "2026-09-21T04:12:23.749Z",
      "location_count": 2,
      "location_summary": "Washington D.C., District of Columbia • Arlington, Virginia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Arlington",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03631030"
    }
  ]
}