{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Rate-drop+condition",
    "query": {
      "intervention": "Rate-drop condition"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 15,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Rate-drop+condition&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-06T15:06:29.426Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01227187",
      "title": "Safety and Dose Finding Study of Xigris in Hemodialysis Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "End Stage Renal Disease"
      ],
      "interventions": [
        {
          "name": "Drotrecogin alfa activated (Xigris)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "George Washington University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 12,
      "start_date": "2008-10",
      "completion_date": "2010-12",
      "has_results": true,
      "last_update_posted_date": "2022-02-03",
      "last_synced_at": "2026-09-06T15:06:29.426Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01227187"
    },
    {
      "nct_id": "NCT05716542",
      "title": "Prehabilitation to Revolutionize Oncology: Telehealth Exercise for Cognitive Triumphs (The PROTECT Trial)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Breast Cancer",
        "Cancer of the Breast"
      ],
      "interventions": [
        {
          "name": "Physical Activity Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 41,
      "start_date": "2023-05-11",
      "completion_date": "2024-10-04",
      "has_results": false,
      "last_update_posted_date": "2025-08-28",
      "last_synced_at": "2026-09-06T15:06:29.426Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05716542"
    },
    {
      "nct_id": "NCT05925101",
      "title": "Basic and Applied Research on Extinction Bursts",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Problem Behavior",
        "Aggression",
        "Self Injury"
      ],
      "interventions": [
        {
          "name": "Extinction-only condition",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Rate-drop condition",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Rate-hold condition",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Magnitude-drop condition",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Magnitude-hold condition",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Quality-drop condition",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Quality-hold condition",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Rate-drop/quality-increase condition",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Rutgers, The State University of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "3 Years to 17 Years"
      },
      "enrollment_count": 40,
      "start_date": "2023-07-07",
      "completion_date": "2028-05-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-29",
      "last_synced_at": "2026-09-06T15:06:29.426Z",
      "location_count": 1,
      "location_summary": "Somerset, New Jersey",
      "locations": [
        {
          "city": "Somerset",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05925101"
    },
    {
      "nct_id": "NCT02435069",
      "title": "A Within Subjects Comparison of Two Antegrade Flushing Regimens in Children",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Fecal Incontinence",
        "Neurogenic Bowel"
      ],
      "interventions": [
        {
          "name": "Dose Response - NS and USP Glycerin - First Intervention",
          "type": "DRUG"
        },
        {
          "name": "Effectiveness - NS and USP Glycerin - Second Intervention",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Nemours Children's Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "3 Years to 12 Years"
      },
      "enrollment_count": 5,
      "start_date": "2016-02-09",
      "completion_date": "2018-03-30",
      "has_results": true,
      "last_update_posted_date": "2019-08-28",
      "last_synced_at": "2026-09-06T15:06:29.426Z",
      "location_count": 1,
      "location_summary": "Jacksonville, Florida",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02435069"
    },
    {
      "nct_id": "NCT01033552",
      "title": "Biochemical Correction of Severe EB by Allo HSCT and \"Off-the-shelf\" MSCs",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Epidermolysis Bullosa"
      ],
      "interventions": [
        {
          "name": "Cyclophosphamide",
          "type": "DRUG"
        },
        {
          "name": "Fludarabine",
          "type": "DRUG"
        },
        {
          "name": "Anti-thymocyte globulin",
          "type": "DRUG"
        },
        {
          "name": "Myeloablative Busulfan",
          "type": "DRUG"
        },
        {
          "name": "Mesenchymal stem cell transplantation",
          "type": "PROCEDURE"
        },
        {
          "name": "Total body irradiation",
          "type": "RADIATION"
        },
        {
          "name": "Bone marrow or umbilical cord blood (UCG) stem cell transplantation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE",
        "RADIATION"
      ],
      "sponsor": "Masonic Cancer Center, University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "25 Years",
        "sex": "ALL",
        "summary": "Up to 25 Years"
      },
      "enrollment_count": 32,
      "start_date": "2010-01",
      "completion_date": "2021-08-12",
      "has_results": true,
      "last_update_posted_date": "2024-04-03",
      "last_synced_at": "2026-09-06T15:06:29.426Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01033552"
    },
    {
      "nct_id": "NCT02525029",
      "title": "Study of Pregnyl as Adjunct Therapy for High-Risk or Refractory Acute GVHD",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Graft vs Host Disease"
      ],
      "interventions": [
        {
          "name": "Pregnyl®",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Masonic Cancer Center, University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "76 Years",
        "sex": "ALL",
        "summary": "Up to 76 Years"
      },
      "enrollment_count": 53,
      "start_date": "2016-03",
      "completion_date": "2022-04",
      "has_results": true,
      "last_update_posted_date": "2023-12-14",
      "last_synced_at": "2026-09-06T15:06:29.426Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02525029"
    },
    {
      "nct_id": "NCT01852383",
      "title": "Duloxetine Treatment in Elderly With Dysthymia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Depression",
        "Dysthymic Disorder"
      ],
      "interventions": [
        {
          "name": "Duloxetine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "New York State Psychiatric Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "95 Years",
        "sex": "ALL",
        "summary": "60 Years to 95 Years"
      },
      "enrollment_count": 30,
      "start_date": "2006-01",
      "completion_date": "2013-03",
      "has_results": true,
      "last_update_posted_date": "2014-05-01",
      "last_synced_at": "2026-09-06T15:06:29.426Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01852383"
    },
    {
      "nct_id": "NCT03704766",
      "title": "Alpha-Defensin and Synovial Proteins to Improve Detection of Pediatric Septic Arthritis",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Joint Infection",
        "Infection of Hip Joint (Disorder)",
        "Infection of Shoulder Joint",
        "Septic Arthritis"
      ],
      "interventions": [
        {
          "name": "Synovial Alpha-defensin assay",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial Neutrophil elastase assay",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial lactate assay",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial C-reactive Protein (CRP)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial Staphylococcus spp antigen panel",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial Candida spp antigen panel",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial Enterococcus faecalis assay",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial bacterial culture by BacT/Alert",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial Cell count + differential (CBC)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial Gram Stain",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial Leukocyte Esterase Test Strips",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial PCR for Kingella kingae",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Serum Cell count + differential (CBC)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Serum erythrocyte sedimentation rate (ESR)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Serum C-reactive Protein (CRP)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Serum D-dimer",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Serum Procalcitonin",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Blood Cultures",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Optional blood testing per standard of care (ASO, anti-strep, ANA, anti-DS-DNA, HLA-B27, RF, Lyme and other inflammatory/ rheumatologic markers )",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Hospital for Special Surgery, New York",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "Up to 17 Years"
      },
      "enrollment_count": 442,
      "start_date": "2016-06-28",
      "completion_date": "2027-01",
      "has_results": false,
      "last_update_posted_date": "2026-07-29",
      "last_synced_at": "2026-09-06T15:06:29.426Z",
      "location_count": 3,
      "location_summary": "Atlanta, Georgia • New York, New York • Collierville, Tennessee",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Collierville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03704766"
    },
    {
      "nct_id": "NCT04838223",
      "title": "Neurosensory Abnormalities in SymptomAtic Ocular Surface Patients (NASA)",
      "overall_status": "SUSPENDED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Dry Eye",
        "Neuropathic Pain"
      ],
      "interventions": [
        {
          "name": "Hyperosmolar Response",
          "type": "OTHER"
        },
        {
          "name": "Proparacaine Challenge Test",
          "type": "OTHER"
        },
        {
          "name": "Contact Lens Dry Eye Questionnaire-8 (CLDEQ-8) Optional; only for Contact Lens Wearers",
          "type": "OTHER"
        },
        {
          "name": "Ocular Pain Assessment Survey (OPAS)",
          "type": "OTHER"
        },
        {
          "name": "Visual Analogue Questionnaire",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Tufts Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1000,
      "start_date": "2021-07-02",
      "completion_date": "2026-07",
      "has_results": false,
      "last_update_posted_date": "2026-01-27",
      "last_synced_at": "2026-09-06T15:06:29.426Z",
      "location_count": 16,
      "location_summary": "Azusa, California • Pomona, California • San Francisco, California + 10 more",
      "locations": [
        {
          "city": "Azusa",
          "state": "California"
        },
        {
          "city": "Pomona",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04838223"
    },
    {
      "nct_id": "NCT06841198",
      "title": "Cardiovascular Function and Response to Stimulation Within the First Year After Spinal Cord Injury",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spinal Cord Injuries (SCI)",
        "Orthostatic Hypotension, Dysautonomic",
        "Cardiovascular",
        "Transcutaneous Spinal Stimulation"
      ],
      "interventions": [
        {
          "name": "spinal cord transcutaneous stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Ice testing",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Kessler Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 15,
      "start_date": "2025-04-01",
      "completion_date": "2026-11",
      "has_results": false,
      "last_update_posted_date": "2026-07-01",
      "last_synced_at": "2026-09-06T15:06:29.426Z",
      "location_count": 1,
      "location_summary": "West Orange, New Jersey",
      "locations": [
        {
          "city": "West Orange",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06841198"
    }
  ]
}