{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=ReNu%C2%AE+Multiplus",
    "query": {
      "intervention": "ReNu® Multiplus"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 9,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-07T12:39:37.699Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00799422",
      "title": "Evaluation of Contact Lenses and Conjunctival Staining in Normal Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Conjunctival Staining"
      ],
      "interventions": [
        {
          "name": "Complete Easy Rub",
          "type": "DEVICE"
        },
        {
          "name": "ReNu MultiPlus",
          "type": "DEVICE"
        },
        {
          "name": "Clear Care",
          "type": "DEVICE"
        },
        {
          "name": "Contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 26,
      "start_date": "2008-11",
      "completion_date": "2009-03",
      "has_results": true,
      "last_update_posted_date": "2012-11-16",
      "last_synced_at": "2026-09-07T12:39:37.699Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00799422"
    },
    {
      "nct_id": "NCT03897712",
      "title": "A Study to Evaluate the Safety and Effectiveness of a Silicone Hydrogel Custom Contact Lens When Compared to Alden Optical HP Sphere Lens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Contact Lens Wear"
      ],
      "interventions": [
        {
          "name": "Custom Samfilcon B Contact Lenses",
          "type": "DEVICE"
        },
        {
          "name": "Alden Optical HP Sphere Contact Lens",
          "type": "DEVICE"
        },
        {
          "name": "ReNu MultiPlus Lubricating and Rewetting Drops",
          "type": "DEVICE"
        },
        {
          "name": "Biotrue Multi-Purpose Solution",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Bausch & Lomb Incorporated",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 84,
      "start_date": "2019-02-27",
      "completion_date": "2019-08-28",
      "has_results": true,
      "last_update_posted_date": "2022-11-14",
      "last_synced_at": "2026-09-07T12:39:37.699Z",
      "location_count": 7,
      "location_summary": "San Francisco, California • Denver, Colorado • Sarasota, Florida + 4 more",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Sarasota",
          "state": "Florida"
        },
        {
          "city": "Pittsburg",
          "state": "Kansas"
        },
        {
          "city": "Warrensburg",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03897712"
    },
    {
      "nct_id": "NCT00789529",
      "title": "Objective Testing of Tear Film Stability",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Contact Lens Solutions"
      ],
      "interventions": [
        {
          "name": "Opti-Free® RepleniSH® MPDS",
          "type": "DEVICE"
        },
        {
          "name": "ReNu MultiPlus®",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Manhattan Vision Associates",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 32,
      "start_date": "2008-09",
      "completion_date": "2008-11",
      "has_results": true,
      "last_update_posted_date": "2013-05-31",
      "last_synced_at": "2026-09-07T12:39:37.699Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00789529"
    },
    {
      "nct_id": "NCT04140279",
      "title": "A Study to Evaluate the Effect of Latanoprostene Bunod Ophthalmic Solution 0.024% on Episcleral Venous Pressure and Outflow Facility in Participants With Ocular Hypertension",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Ocular Hypertension"
      ],
      "interventions": [
        {
          "name": "Latanoprostene Bunod",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Bausch & Lomb Incorporated",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2022-05-13",
      "completion_date": "2023-08",
      "has_results": false,
      "last_update_posted_date": "2024-03-04",
      "last_synced_at": "2026-09-07T12:39:37.699Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04140279"
    },
    {
      "nct_id": "NCT01250925",
      "title": "Effect of Contact Lens Wear on Immune Cell Density and Morphology of the Ocular Surface",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Myopia",
        "Refractive Error"
      ],
      "interventions": [
        {
          "name": "ReNu MultiPlus® MultiPurpose Solution",
          "type": "DRUG"
        },
        {
          "name": "OPTI-FREE® RepleniSH®",
          "type": "DRUG"
        },
        {
          "name": "Clear Care®",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Massachusetts Eye and Ear Infirmary",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 94,
      "start_date": "2010-08",
      "completion_date": "2012-07",
      "has_results": true,
      "last_update_posted_date": "2017-01-10",
      "last_synced_at": "2026-09-07T12:39:37.699Z",
      "location_count": 2,
      "location_summary": "Iowa City, Iowa • Boston, Massachusetts",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01250925"
    },
    {
      "nct_id": "NCT01699750",
      "title": "Comparative In-Vivo Wetting Characteristics of Silicone Hydrogel Materials With Selected Lens Care Systems",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia",
        "Astigmatism",
        "Refractive Error"
      ],
      "interventions": [
        {
          "name": "Lotrafilcon B contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Senofilcon A contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "OPTI-FREE® PUREMOIST® MPDS",
          "type": "DEVICE"
        },
        {
          "name": "BIOTRUE®",
          "type": "DEVICE"
        },
        {
          "name": "Balafilcon A contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "ReNu® Multiplus®",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 109,
      "start_date": "2012-12",
      "completion_date": "2013-11",
      "has_results": true,
      "last_update_posted_date": "2014-12-08",
      "last_synced_at": "2026-09-07T12:39:37.699Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01699750"
    },
    {
      "nct_id": "NCT03537248",
      "title": "A Safety and Effectiveness Study of a New Multi-Purpose Contact Lens Care Solution",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Contact Lens Wear"
      ],
      "interventions": [
        {
          "name": "ASP-57",
          "type": "DEVICE"
        },
        {
          "name": "ReNu® Multiplus",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Asepticys LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 315,
      "start_date": "2018-04-23",
      "completion_date": "2018-10-30",
      "has_results": false,
      "last_update_posted_date": "2019-02-11",
      "last_synced_at": "2026-09-07T12:39:37.699Z",
      "location_count": 14,
      "location_summary": "Irvine, California • San Diego, California • Longwood, Florida + 11 more",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Longwood",
          "state": "Florida"
        },
        {
          "city": "Maitland",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03537248"
    },
    {
      "nct_id": "NCT01341990",
      "title": "Effect of an Investigational Multi-Purpose Solution on Lens Moisture",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Contact Lens Moisture"
      ],
      "interventions": [
        {
          "name": "FID 114675A Multi-Purpose Disinfecting Solution (MPDS)",
          "type": "DEVICE"
        },
        {
          "name": "ReNu Fresh Lens Comfort Multi-Purpose Solution (MPS)",
          "type": "DEVICE"
        },
        {
          "name": "Silicone Hydrogel Contact Lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 68,
      "start_date": "2009-11",
      "completion_date": "2010-01",
      "has_results": true,
      "last_update_posted_date": "2012-04-13",
      "last_synced_at": "2026-09-07T12:39:37.699Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01341990"
    },
    {
      "nct_id": "NCT00772707",
      "title": "A Multi-Center Investigation of Patient Acceptability of OPTI-FREE RepleniSH® Multi-Purpose Disinfecting Solution (MPDS)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia"
      ],
      "interventions": [
        {
          "name": "Multi-Purpose Disinfecting Solution (OPTI-FREE RepleniSH)",
          "type": "DEVICE"
        },
        {
          "name": "Contact Lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 114,
      "start_date": "2008-09",
      "completion_date": "2008-10",
      "has_results": true,
      "last_update_posted_date": "2012-09-07",
      "last_synced_at": "2026-09-07T12:39:37.699Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00772707"
    }
  ]
}