{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Recombinant+influenza+vaccine+%28RIV4%29", "query": { "intervention": "Recombinant influenza vaccine (RIV4)" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 13, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Recombinant+influenza+vaccine+%28RIV4%29&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-10-06T16:42:21.323Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02434276", "title": "Study of the Immunogenicity and Safety of a Quadrivalent Influenza Vaccine (VAX2012Q) in Adults 18-64 Years", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Influenza" ], "interventions": [ { "name": "VAX2012Q", "type": "BIOLOGICAL" }, { "name": "Fluzone Quadrivalent", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "VaxInnate Corporation", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "64 Years", "sex": "ALL", "summary": "18 Years to 64 Years" }, "enrollment_count": 450, "start_date": "2015-05", "completion_date": "2016-06", "has_results": false, "last_update_posted_date": "2015-06-26", "last_synced_at": "2026-10-06T16:42:21.323Z", "location_count": 6, "location_summary": "Huntsville, Alabama • San Diego, California • Melbourne, Florida + 3 more", "locations": [ { "city": "Huntsville", "state": "Alabama" }, { "city": "San Diego", "state": "California" }, { "city": "Melbourne", "state": "Florida" }, { "city": "Peoria", "state": "Illinois" }, { "city": "Mishawaka", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT02434276" }, { "nct_id": "NCT06118151", "title": "Safety and Immunogenicity of a Monovalent mRNA Vaccine Encoding Influenza Hemagglutinin in Adult Participants 18 Years of Age and Older", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Influenza", "Influenza Immunization" ], "interventions": [ { "name": "Influenza Hemagglutinin mRNA vaccine", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Recombinant Influenza Vaccine", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Sanofi Pasteur, a Sanofi Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 388, "start_date": "2022-04-11", "completion_date": "2023-02-17", "has_results": false, "last_update_posted_date": "2023-11-07", "last_synced_at": "2026-10-06T16:42:21.323Z", "location_count": 20, "location_summary": "Rolling Hills Estates, California • San Diego, California • Coral Gables, Florida + 14 more", "locations": [ { "city": "Rolling Hills Estates", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Coral Gables", "state": "Florida" }, { "city": "Hollywood", "state": "Florida" }, { "city": "Savannah", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT06118151" }, { "nct_id": "NCT04576702", "title": "Safety and Immunogenicity of an MF59-Adjuvanted Influenza Vaccine in Older Adults", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Influenza", "Human" ], "interventions": [ { "name": "Investigational aIIV4c", "type": "BIOLOGICAL" }, { "name": "IIV4c", "type": "BIOLOGICAL" }, { "name": "aIIV4", "type": "BIOLOGICAL" }, { "name": "RIV4", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Seqirus", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "50 Years", "maximum_age": null, "sex": "ALL", "summary": "50 Years and older" }, "enrollment_count": 471, "start_date": "2020-10-08", "completion_date": "2021-05-24", "has_results": true, "last_update_posted_date": "2024-04-17", "last_synced_at": "2026-10-06T16:42:21.323Z", "location_count": 21, "location_summary": "Mobile, Alabama • Tempe, Arizona • Jacksonville, Florida + 17 more", "locations": [ { "city": "Mobile", "state": "Alabama" }, { "city": "Tempe", "state": "Arizona" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Oakland", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT04576702" }, { "nct_id": "NCT03969641", "title": "Safety of RIV4 Versus IIV4 in Pregnant Women", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Safety", "Adverse Event Following Immunisation", "Birth Outcomes" ], "interventions": [ { "name": "Quadrivalent Recombinant Influenza Vaccine", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Inactivated Influenza Vaccine", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 384, "start_date": "2019-09-05", "completion_date": "2021-09-29", "has_results": true, "last_update_posted_date": "2023-01-11", "last_synced_at": "2026-10-06T16:42:21.323Z", "location_count": 3, "location_summary": "Boston, Massachusetts • Durham, North Carolina • Cincinnati, Ohio", "locations": [ { "city": "Boston", "state": "Massachusetts" }, { "city": "Durham", "state": "North Carolina" }, { "city": "Cincinnati", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT03969641" }, { "nct_id": "NCT05650554", "title": "Safety and Immunogenicity of Quadrivalent Influenza mRNA Vaccine MRT5413 in Adult Participants18 Years of Age and Older", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Influenza Immunization" ], "interventions": [ { "name": "Quadrivalent Influenza mRNA Vaccine MRT5413", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Recombinant Influenza Vaccine", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Influenza Standard Dose Vaccine", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Influenza High-Dose Vaccine", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Sanofi Pasteur, a Sanofi Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 682, "start_date": "2022-12-12", "completion_date": "2024-04-02", "has_results": false, "last_update_posted_date": "2025-03-19", "last_synced_at": "2026-10-06T16:42:21.323Z", "location_count": 28, "location_summary": "Chula Vista, California • Gardena, California • Long Beach, California + 24 more", "locations": [ { "city": "Chula Vista", "state": "California" }, { "city": "Gardena", "state": "California" }, { "city": "Long Beach", "state": "California" }, { "city": "North Hollywood", "state": "California" }, { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05650554" }, { "nct_id": "NCT06361875", "title": "A Study to Investigate the Safety and Immunogenicity of the Quadrivalent Influenza mRNA Vaccines in Adults Aged 18 Years and Above", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Influenza Immunization", "Healthy Volunteers" ], "interventions": [ { "name": "Quadrivalent Influenza mRNA Vaccine MRT5421", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Influenza mRNA Vaccine MRT5424", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Influenza mRNA Vaccine MRT5429", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Influenza Standard Dose Vaccine", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Influenza High-Dose Vaccine", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Recombinant Influenza Vaccine", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Sanofi Pasteur, a Sanofi Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 908, "start_date": "2024-04-01", "completion_date": "2025-06-09", "has_results": true, "last_update_posted_date": "2026-08-04", "last_synced_at": "2026-10-06T16:42:21.323Z", "location_count": 11, "location_summary": "San Diego, California • Hialeah, Florida • Hollywood, Florida + 8 more", "locations": [ { "city": "San Diego", "state": "California" }, { "city": "Hialeah", "state": "Florida" }, { "city": "Hollywood", "state": "Florida" }, { "city": "Indianapolis", "state": "Indiana" }, { "city": "Lexington", "state": "Kentucky" } ], "official_url": "https://clinicaltrials.gov/study/NCT06361875" }, { "nct_id": "NCT01959945", "title": "Safety, Reactogenicity and Immunogenicity of Flublok Quadrivalent (Recombinant Influenza Vaccine,Seasonal Formulation)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Influenza" ], "interventions": [ { "name": "Flublok® Quadrivalent Influenza Virus Vaccine", "type": "BIOLOGICAL" }, { "name": "Fluarix Quadrivalent® Influenza Virus Vaccine", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Protein Sciences Corporation", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "6 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "6 Years to 17 Years" }, "enrollment_count": 219, "start_date": "2013-11", "completion_date": "2014-10", "has_results": true, "last_update_posted_date": "2016-09-23", "last_synced_at": "2026-10-06T16:42:21.323Z", "location_count": 1, "location_summary": "Auburn, Maine", "locations": [ { "city": "Auburn", "state": "Maine" } ], "official_url": "https://clinicaltrials.gov/study/NCT01959945" }, { "nct_id": "NCT03598439", "title": "Randomized Influenza Vaccine Evaluation of Immune Response", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Influenza" ], "interventions": [ { "name": "Standard IIV4", "type": "BIOLOGICAL" }, { "name": "Recombinant", "type": "BIOLOGICAL" }, { "name": "Cell-culture", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Marshfield Clinic Research Foundation", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "64 Years", "sex": "ALL", "summary": "18 Years to 64 Years" }, "enrollment_count": 366, "start_date": "2018-07-30", "completion_date": "2024-07-09", "has_results": false, "last_update_posted_date": "2025-11-21", "last_synced_at": "2026-10-06T16:42:21.323Z", "location_count": 1, "location_summary": "Marshfield, Wisconsin", "locations": [ { "city": "Marshfield", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT03598439" }, { "nct_id": "NCT05513053", "title": "Study With Quadrivalent Recombinant Influenza Vaccine (RIV4) in Participants 9 Through 49 Years of Age.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Influenza Immunization" ], "interventions": [ { "name": "Quadrivalent Recombinant influenza vaccine (RIV4) season/2022-2023/NH", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Sanofi Pasteur, a Sanofi Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "9 Years", "maximum_age": "49 Years", "sex": "ALL", "summary": "9 Years to 49 Years" }, "enrollment_count": 1308, "start_date": "2022-10-27", "completion_date": "2023-10-27", "has_results": true, "last_update_posted_date": "2025-09-09", "last_synced_at": "2026-10-06T16:42:21.323Z", "location_count": 21, "location_summary": "Birmingham, Alabama • Jonesboro, Arkansas • San Diego, California + 16 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Jonesboro", "state": "Arkansas" }, { "city": "San Diego", "state": "California" }, { "city": "Sioux City", "state": "Iowa" } ], "official_url": "https://clinicaltrials.gov/study/NCT05513053" }, { "nct_id": "NCT05624606", "title": "Safety and Immunogenicity of Quadrivalent Influenza mRNA Vaccine MRT5410 in Adult Participants 18 Years of Age and Older", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Influenza Immunization" ], "interventions": [ { "name": "Quadrivalent Influenza mRNA Vaccine MRT5410", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Recombinant Influenza vaccine RIV4", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Inactivated Influenza Standard Dose QIV-SD", "type": "BIOLOGICAL" }, { "name": "Quadrivalent Inactivated Influenza High Dose QIV-HD", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Sanofi Pasteur, a Sanofi Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 682, "start_date": "2022-11-28", "completion_date": "2024-03-28", "has_results": false, "last_update_posted_date": "2025-03-18", "last_synced_at": "2026-10-06T16:42:21.323Z", "location_count": 23, "location_summary": "Huntington Park, California • Long Beach, California • North Hollywood, California + 19 more", "locations": [ { "city": "Huntington Park", "state": "California" }, { "city": "Long Beach", "state": "California" }, { "city": "North Hollywood", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Gainesville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT05624606" } ] }