{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Reduced+calorie+American+Diet",
    "query": {
      "intervention": "Reduced calorie American Diet"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 20,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Reduced+calorie+American+Diet&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-29T15:30:39.636Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03685305",
      "title": "Weight Loss and Cognitive Function in Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Overweight and Obesity"
      ],
      "interventions": [
        {
          "name": "Hypocaloric diet with hunger reduction strategy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Hypocaloric diet without hunger reduction strategy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Virginia Polytechnic Institute and State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "50 Years to 75 Years"
      },
      "enrollment_count": 33,
      "start_date": "2018-08-06",
      "completion_date": "2020-03-31",
      "has_results": false,
      "last_update_posted_date": "2025-03-21",
      "last_synced_at": "2026-09-29T15:30:39.636Z",
      "location_count": 1,
      "location_summary": "Blacksburg, Virginia",
      "locations": [
        {
          "city": "Blacksburg",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03685305"
    },
    {
      "nct_id": "NCT03074643",
      "title": "Utilizing Protein During Weight Loss to Impact Physical Function",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Weight Loss",
        "Diet Modification",
        "Aging",
        "Weight Change, Body",
        "Dietary Habits"
      ],
      "interventions": [
        {
          "name": "Weight loss intervention months 0-6",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Exercise intervention months 0-6",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Carbohydrate supplement for months 0-6",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Protein supplement for months 0-6",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Protein supplement for follow-up months 7-18",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "65 Years to 85 Years"
      },
      "enrollment_count": 187,
      "start_date": "2017-05-03",
      "completion_date": "2022-04-28",
      "has_results": true,
      "last_update_posted_date": "2023-05-22",
      "last_synced_at": "2026-09-29T15:30:39.636Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03074643"
    },
    {
      "nct_id": "NCT06730633",
      "title": "Collaborate and Leverage Evidence in African American Rural Network",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiovascular Diseases"
      ],
      "interventions": [
        {
          "name": "Heart Matters",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 173,
      "start_date": "2025-02-22",
      "completion_date": "2026-08-17",
      "has_results": false,
      "last_update_posted_date": "2026-08-28",
      "last_synced_at": "2026-09-29T15:30:39.636Z",
      "location_count": 9,
      "location_summary": "Enfield, North Carolina • Nashville, North Carolina • Rocky Mount, North Carolina + 3 more",
      "locations": [
        {
          "city": "Enfield",
          "state": "North Carolina"
        },
        {
          "city": "Nashville",
          "state": "North Carolina"
        },
        {
          "city": "Rocky Mount",
          "state": "North Carolina"
        },
        {
          "city": "Rocky Mount",
          "state": "North Carolina"
        },
        {
          "city": "Rocky Mount",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06730633"
    },
    {
      "nct_id": "NCT01897090",
      "title": "A Crohn's Disease Diet to Reduce Symptoms of Crohn's Disease",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Crohn's Disease"
      ],
      "interventions": [
        {
          "name": "Elimination Diet",
          "type": "OTHER"
        },
        {
          "name": "Dietary Guidelines for Americans",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 0,
      "start_date": "2013-01",
      "completion_date": "2014-01",
      "has_results": false,
      "last_update_posted_date": "2016-04-05",
      "last_synced_at": "2026-09-29T15:30:39.636Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01897090"
    },
    {
      "nct_id": "NCT04230928",
      "title": "Giving a Low Carbohydrate Diet to Overcome Hypertension",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypertension",
        "African Americans",
        "Diet, Carbohydrate-Restricted",
        "Risk Reduction Behavior"
      ],
      "interventions": [
        {
          "name": "Very low carbohydrate diet",
          "type": "OTHER"
        },
        {
          "name": "Standard DPP-GLB diet",
          "type": "OTHER"
        },
        {
          "name": "Standard DPP-GLB program modules",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "Baylor Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "74 Years",
        "sex": "ALL",
        "summary": "18 Years to 74 Years"
      },
      "enrollment_count": 64,
      "start_date": "2020-03-05",
      "completion_date": "2023-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-03-02",
      "last_synced_at": "2026-09-29T15:30:39.636Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04230928"
    },
    {
      "nct_id": "NCT02365324",
      "title": "Peer Education About Weight Steadiness",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Physical Activity"
      ],
      "interventions": [
        {
          "name": "Peer-Education Family Fitness Program (PE-FFP)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Family Fitness Program (FFP)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Illinois at Urbana-Champaign",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "11 Years",
        "maximum_age": "14 Years",
        "sex": "ALL",
        "summary": "11 Years to 14 Years"
      },
      "enrollment_count": 200,
      "start_date": "2015-05",
      "completion_date": "2018-05",
      "has_results": false,
      "last_update_posted_date": "2019-09-04",
      "last_synced_at": "2026-09-29T15:30:39.636Z",
      "location_count": 4,
      "location_summary": "Champaign, Illinois • Mahomet, Illinois • Urbana, Illinois",
      "locations": [
        {
          "city": "Champaign",
          "state": "Illinois"
        },
        {
          "city": "Champaign",
          "state": "Illinois"
        },
        {
          "city": "Mahomet",
          "state": "Illinois"
        },
        {
          "city": "Urbana",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02365324"
    },
    {
      "nct_id": "NCT02835092",
      "title": "Weight Loss Using the Take Shape For Life Program or the Medifast Direct Program Versus a Self-Directed Diet",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Overweight",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Take Shape For Life Program",
          "type": "OTHER"
        },
        {
          "name": "Medifast Direct Program",
          "type": "OTHER"
        },
        {
          "name": "Self-directed Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Medifast, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 198,
      "start_date": "2016-07",
      "completion_date": "2017-02",
      "has_results": true,
      "last_update_posted_date": "2019-01-22",
      "last_synced_at": "2026-09-29T15:30:39.636Z",
      "location_count": 1,
      "location_summary": "Addison, Illinois",
      "locations": [
        {
          "city": "Addison",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02835092"
    },
    {
      "nct_id": "NCT00599040",
      "title": "The DINE Study-Diet Intervention to Negate Diabetes Study (Improving Weight Loss Outcomes for African Americans)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Diabetes",
        "Hypertension",
        "Insulin Resistance"
      ],
      "interventions": [
        {
          "name": "The DASH diet with weight loss",
          "type": "BEHAVIORAL"
        },
        {
          "name": "The DASH diet without weight loss",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Dairy diet",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 113,
      "start_date": "2005-09",
      "completion_date": "2010-12",
      "has_results": false,
      "last_update_posted_date": "2013-03-18",
      "last_synced_at": "2026-09-29T15:30:39.636Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00599040"
    },
    {
      "nct_id": "NCT00422630",
      "title": "The Metabolic Effects of Different Weight Loss Diets",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Metabolic Syndrome X",
        "Obesity",
        "Insulin Resistance",
        "Hypertension",
        "Diabetes"
      ],
      "interventions": [
        {
          "name": "The DASH diet",
          "type": "BEHAVIORAL"
        },
        {
          "name": "The low glycemic Index Diet",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Reduced calorie American Diet",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Rockefeller University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 18,
      "start_date": "2007-10",
      "completion_date": "2010-02",
      "has_results": false,
      "last_update_posted_date": "2011-10-13",
      "last_synced_at": "2026-09-29T15:30:39.636Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00422630"
    },
    {
      "nct_id": "NCT03819478",
      "title": "Utilizing Protein During Weight Loss to Impact Physical Function and Bone",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Weight Loss",
        "Diet Modification",
        "Aging",
        "Weight Change, Body",
        "Dietary Habits",
        "Osteopenia, Osteoporosis",
        "Bone Loss",
        "Fractures, Bone"
      ],
      "interventions": [
        {
          "name": "Weight loss intervention months 0-6",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Exercise intervention months 0-6",
          "type": "BEHAVIORAL"
        },
        {
          "name": "NutraBio™ CarboMax Supplement",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "6-month NutraBio™ 100% Whey Protein Isolate Supplement",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "18-month NutraBio™ 100% Whey Protein Isolate Supplement",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "65 Years to 85 Years"
      },
      "enrollment_count": 187,
      "start_date": "2017-05-03",
      "completion_date": "2022-04-28",
      "has_results": true,
      "last_update_posted_date": "2024-01-19",
      "last_synced_at": "2026-09-29T15:30:39.636Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03819478"
    }
  ]
}