{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Reduced+fluid+volume&page=2", "query": { "intervention": "Reduced fluid volume", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Reduced+fluid+volume&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-09-26T07:59:44.225Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03625492", "title": "Fluids Affecting Bladder Urgency and Lower Urinary Symptoms", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Overactive Bladder", "Urinary Urgency", "Urinary Bladder, Overactive", "Urinary Incontinence, Urge", "Caffeine", "Alcohol Drinking", "Lower Urinary Tract Symptoms" ], "interventions": [ { "name": "Reducing Potentially Irritating Beverages", "type": "BEHAVIORAL" }, { "name": "Adopting the USDA Healthy Eating Habits", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "University of Michigan", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 65, "start_date": "2018-08-07", "completion_date": "2019-09-17", "has_results": false, "last_update_posted_date": "2019-11-14", "last_synced_at": "2026-09-26T07:59:44.225Z", "location_count": 1, "location_summary": "Ann Arbor, Michigan", "locations": [ { "city": "Ann Arbor", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT03625492" }, { "nct_id": "NCT04163614", "title": "Blood Pressure Slopes and Ultrafiltration in Hemodialysis Patients", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "End Stage Renal Disease", "Hypertension", "Extracellular Volume Overload", "Intradialytic Hypotension" ], "interventions": [ { "name": "IBPS-Guided Ultrafiltration", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "VA Office of Research and Development", "sponsor_class": "FED", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 69, "start_date": "2021-02-10", "completion_date": "2026-10-01", "has_results": false, "last_update_posted_date": "2026-07-20", "last_synced_at": "2026-09-26T07:59:44.225Z", "location_count": 1, "location_summary": "Dallas, Texas", "locations": [ { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04163614" }, { "nct_id": "NCT00727740", "title": "A Double-blind Study to Determine if Intraduodenal Indomethacin Can Decrease the Incidence of Post-ERCP Pancreatitis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Pancreatitis" ], "interventions": [ { "name": "Indomethacin", "type": "DRUG" }, { "name": "Placebo suspension", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Yale University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 117, "start_date": "2005-08", "completion_date": "2012-08", "has_results": true, "last_update_posted_date": "2017-01-18", "last_synced_at": "2026-09-26T07:59:44.225Z", "location_count": 1, "location_summary": "New Haven, Connecticut", "locations": [ { "city": "New Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT00727740" }, { "nct_id": "NCT07131592", "title": "Effect of Intravenous and Topical Tranexamic Acid on Drain Output in Breast Reduction Surgery", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Drain Output After Breast Reduction Surgery", "Breast Reductions" ], "interventions": [ { "name": "IV TXA", "type": "DRUG" }, { "name": "Topical TXA", "type": "DRUG" }, { "name": "Topical saline", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 160, "start_date": "2025-11-18", "completion_date": "2027-08-31", "has_results": false, "last_update_posted_date": "2026-01-16", "last_synced_at": "2026-09-26T07:59:44.225Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT07131592" }, { "nct_id": "NCT01866657", "title": "Cerebral Oximetry in Single Lung Ventilation Thoracic Surgery", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Hypoxia" ], "interventions": [ { "name": "Vasoconstrictor Agents", "type": "DRUG" }, { "name": "Head/neck repositioning", "type": "OTHER" }, { "name": "Increase ETCO2", "type": "OTHER" }, { "name": "IV fluid bolus", "type": "OTHER" }, { "name": "Additional anesthesia", "type": "DRUG" }, { "name": "RBC transfusion", "type": "BIOLOGICAL" }, { "name": "Increase FiO2", "type": "DRUG" } ], "intervention_types": [ "DRUG", "OTHER", "BIOLOGICAL" ], "sponsor": "University Hospitals Cleveland Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "65 Years", "maximum_age": null, "sex": "ALL", "summary": "65 Years and older" }, "enrollment_count": 74, "start_date": "2013-06", "completion_date": "2016-11-10", "has_results": true, "last_update_posted_date": "2022-07-05", "last_synced_at": "2026-09-26T07:59:44.225Z", "location_count": 1, "location_summary": "Cleveland, Ohio", "locations": [ { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT01866657" }, { "nct_id": "NCT03252145", "title": "Treatment of Breast Cancer-related Lymphedema With a Negative Pressure Device", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Lymphedema, Secondary", "Lymphedema of Upper Limb" ], "interventions": [ { "name": "PhysioTouch", "type": "DEVICE" }, { "name": "Manual Lymph Drainage (MLD)", "type": "OTHER" } ], "intervention_types": [ "DEVICE", "OTHER" ], "sponsor": "University of California, San Francisco", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 28, "start_date": "2017-10-31", "completion_date": "2020-01-31", "has_results": true, "last_update_posted_date": "2021-01-15", "last_synced_at": "2026-09-26T07:59:44.225Z", "location_count": 1, "location_summary": "San Francisco, California", "locations": [ { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03252145" }, { "nct_id": "NCT03556293", "title": "IMPROVE AKI Cluster-Randomized Trial", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Acute Kidney Injury" ], "interventions": [ { "name": "AKI Prevention Toolkit", "type": "BEHAVIORAL" }, { "name": "Technical Assistance (TA)", "type": "BEHAVIORAL" }, { "name": "Virtual Learning Collaborative (VLC)", "type": "BEHAVIORAL" }, { "name": "Automated Surveillance Reporting (ASR)", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Dartmouth-Hitchcock Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 10252, "start_date": "2019-09-01", "completion_date": "2023-01-31", "has_results": true, "last_update_posted_date": "2025-03-18", "last_synced_at": "2026-09-26T07:59:44.225Z", "location_count": 2, "location_summary": "Nashville, Tennessee • White River Junction, Vermont", "locations": [ { "city": "Nashville", "state": "Tennessee" }, { "city": "White River Junction", "state": "Vermont" } ], "official_url": "https://clinicaltrials.gov/study/NCT03556293" }, { "nct_id": "NCT02186938", "title": "A Prospective Study Evaluating the Use of Intraoperative Stroke Volume Variation Via the FloTrac Device to Guide Fluid and Vasopressor Management in Head and Neck Free Flaps", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Head and Neck Cancer", "Patients Requiring a Free Flap Surgery" ], "interventions": [ { "name": "FloTrac", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Medical University of South Carolina", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 94, "start_date": "2012-12", "completion_date": "2014-10", "has_results": true, "last_update_posted_date": "2018-09-20", "last_synced_at": "2026-09-26T07:59:44.225Z", "location_count": 1, "location_summary": "Charleston, South Carolina", "locations": [ { "city": "Charleston", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT02186938" }, { "nct_id": "NCT02623660", "title": "Microcurrent Stimulation Reduces Post-Operative Swelling and Healing Time Following Knee Replacement Surgery", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Osteoarthritis of Knee", "Edema", "Wounds and Injuries" ], "interventions": [ { "name": "ODIN1", "type": "DEVICE" }, { "name": "Standard Care", "type": "OTHER" }, { "name": "Diagnostic Device Testing", "type": "DEVICE" } ], "intervention_types": [ "DEVICE", "OTHER" ], "sponsor": "Bioelectric Research Corporation", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 40, "start_date": "2016-01", "completion_date": "2016-10", "has_results": false, "last_update_posted_date": "2016-01-12", "last_synced_at": "2026-09-26T07:59:44.225Z", "location_count": 2, "location_summary": "Las Vegas, Nevada", "locations": [ { "city": "Las Vegas", "state": "Nevada" }, { "city": "Las Vegas", "state": "Nevada" } ], "official_url": "https://clinicaltrials.gov/study/NCT02623660" }, { "nct_id": "NCT03952637", "title": "A Phase 1/2 Study of Intravenous Gene Transfer With an AAV9 Vector Expressing Human Beta-galactosidase in Type I and Type II GM1 Gangliosidosis", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Lysosomal Diseases", "Gangliosidosis", "GM1" ], "interventions": [ { "name": "AAV9-GLB1", "type": "BIOLOGICAL" }, { "name": "Abdominal ultrasound", "type": "PROCEDURE" }, { "name": "Rituximab", "type": "DRUG" }, { "name": "Sirolimus", "type": "DRUG" }, { "name": "Methylprednisolone", "type": "DRUG" }, { "name": "Prednisone", "type": "DRUG" }, { "name": "Audiology assessment with ABR", "type": "DIAGNOSTIC_TEST" }, { "name": "Bone density scan (DEXA)", "type": "DIAGNOSTIC_TEST" }, { "name": "Electrocardiogram (EKG)", "type": "DIAGNOSTIC_TEST" }, { "name": "Echocardiogram", "type": "DIAGNOSTIC_TEST" }, { "name": "Electroencephalogram (EEG) awake and extended overnight", "type": "OTHER" }, { "name": "Laboratory tests", "type": "DIAGNOSTIC_TEST" }, { "name": "Lumbar puncture", "type": "PROCEDURE" }, { "name": "Brain MRI/MRS/fMRI", "type": "PROCEDURE" }, { "name": "Neurocognitive testing", "type": "BEHAVIORAL" }, { "name": "Neurology exam", "type": "OTHER" }, { "name": "PICC or other Central line placement", "type": "BEHAVIORAL" }, { "name": "Skeletal survey", "type": "PROCEDURE" }, { "name": "Skin biopsy", "type": "PROCEDURE" }, { "name": "Speech and modified barium swallow study", "type": "PROCEDURE" }, { "name": "Ophthalmology exam", "type": "PROCEDURE" } ], "intervention_types": [ "BIOLOGICAL", "PROCEDURE", "DRUG", "DIAGNOSTIC_TEST", "OTHER", "BEHAVIORAL" ], "sponsor": "National Human Genome Research Institute (NHGRI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Months", "maximum_age": "12 Years", "sex": "ALL", "summary": "6 Months to 12 Years" }, "enrollment_count": 54, "start_date": "2019-08-19", "completion_date": "2030-01-01", "has_results": false, "last_update_posted_date": "2026-09-21", "last_synced_at": "2026-09-26T07:59:44.225Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT03952637" } ] }