{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Reduced-energy-density+diet",
    "query": {
      "intervention": "Reduced-energy-density diet"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 13,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Reduced-energy-density+diet&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-17T01:10:44.609Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04424537",
      "title": "SOAR-2: Intervening in Obesity Through Reduction of Dietary Branched Chain Amino Acids",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Obesity",
        "Diabetes"
      ],
      "interventions": [
        {
          "name": "Control diet",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Low branched-chain amino acids(BCAA) diet",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Low protein diet",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "30 Years to 65 Years"
      },
      "enrollment_count": 0,
      "start_date": "2024-01",
      "completion_date": "2028-01",
      "has_results": false,
      "last_update_posted_date": "2022-08-04",
      "last_synced_at": "2026-09-17T01:10:44.609Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04424537"
    },
    {
      "nct_id": "NCT05207982",
      "title": "Weight Management Program for Patients With First Episode Psychosis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Diet, Healthy",
        "Psychotic Disorders"
      ],
      "interventions": [
        {
          "name": "Family Based weight management program",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "State University of New York at Buffalo",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "26 Years",
        "sex": "ALL",
        "summary": "14 Years to 26 Years"
      },
      "enrollment_count": 10,
      "start_date": "2022-07-15",
      "completion_date": "2023-07-05",
      "has_results": true,
      "last_update_posted_date": "2025-01-14",
      "last_synced_at": "2026-09-17T01:10:44.609Z",
      "location_count": 1,
      "location_summary": "Buffalo, New York",
      "locations": [
        {
          "city": "Buffalo",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05207982"
    },
    {
      "nct_id": "NCT05649176",
      "title": "Lifestyle Intervention for Improving Insulin Resistance and Concern for Health",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Insulin Sensitivity",
        "Apathy"
      ],
      "interventions": [
        {
          "name": "Diet without soy",
          "type": "OTHER"
        },
        {
          "name": "Diet with soy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Pennington Biomedical Research Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "50 Years to 75 Years"
      },
      "enrollment_count": 40,
      "start_date": "2023-02-13",
      "completion_date": "2025-10-27",
      "has_results": false,
      "last_update_posted_date": "2026-09-09",
      "last_synced_at": "2026-09-17T01:10:44.609Z",
      "location_count": 1,
      "location_summary": "Baton Rouge, Louisiana",
      "locations": [
        {
          "city": "Baton Rouge",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05649176"
    },
    {
      "nct_id": "NCT03085511",
      "title": "High Quality Protein for Assisting With Weight Loss",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Egg breakfast (EB)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Weight Loss Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Weight Loss Diet",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cereal Breakfast (CB)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Texas Tech University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "44 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 44 Years · Female only"
      },
      "enrollment_count": 40,
      "start_date": "2017-08-20",
      "completion_date": "2019-05-17",
      "has_results": false,
      "last_update_posted_date": "2019-05-30",
      "last_synced_at": "2026-09-17T01:10:44.609Z",
      "location_count": 1,
      "location_summary": "Lubbock, Texas",
      "locations": [
        {
          "city": "Lubbock",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03085511"
    },
    {
      "nct_id": "NCT01165086",
      "title": "Reducing Dietary Energy Density by Incorporating Vegetables in Order to Decrease Energy Intake",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Incorporating vegetables into the diet to reduce energy density",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Penn State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "20 Years to 45 Years"
      },
      "enrollment_count": 48,
      "start_date": "2009-11",
      "completion_date": "2010-12",
      "has_results": false,
      "last_update_posted_date": "2011-11-10",
      "last_synced_at": "2026-09-17T01:10:44.609Z",
      "location_count": 1,
      "location_summary": "University Park, Pennsylvania",
      "locations": [
        {
          "city": "University Park",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01165086"
    },
    {
      "nct_id": "NCT00108784",
      "title": "Factors Affecting Caloric Regulation in Human Feeding",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Reduced-energy-density diet",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "20 Years to 60 Years · Female only"
      },
      "enrollment_count": 100,
      "start_date": "2003-03",
      "completion_date": "2004-07",
      "has_results": false,
      "last_update_posted_date": "2010-01-13",
      "last_synced_at": "2026-09-17T01:10:44.609Z",
      "location_count": 1,
      "location_summary": "State College, Pennsylvania",
      "locations": [
        {
          "city": "State College",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00108784"
    },
    {
      "nct_id": "NCT00204477",
      "title": "Soy Protein and Breast Cancer Risk Reduction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Breast Cancer"
      ],
      "interventions": [
        {
          "name": "soy milk",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "cow's milk",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "The University of Texas Medical Branch, Galveston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "30 Years to 40 Years · Female only"
      },
      "enrollment_count": 321,
      "start_date": "2002-04",
      "completion_date": "2023-05-29",
      "has_results": true,
      "last_update_posted_date": "2024-01-23",
      "last_synced_at": "2026-09-17T01:10:44.609Z",
      "location_count": 1,
      "location_summary": "Galveston, Texas",
      "locations": [
        {
          "city": "Galveston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00204477"
    },
    {
      "nct_id": "NCT01304615",
      "title": "Foundations for Health",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Overweight",
        "Obese"
      ],
      "interventions": [
        {
          "name": "Decrease Energy Density of the Diet",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Increase Steps per Day",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Consumption of Self-made Meals",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "The University of Tennessee, Knoxville",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 10,
      "start_date": "2011-02",
      "completion_date": "2011-12",
      "has_results": false,
      "last_update_posted_date": "2018-04-05",
      "last_synced_at": "2026-09-17T01:10:44.609Z",
      "location_count": 1,
      "location_summary": "Knoxville, Tennessee",
      "locations": [
        {
          "city": "Knoxville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01304615"
    },
    {
      "nct_id": "NCT05410574",
      "title": "Family-Based Behavioral Treatment for Childhood Survivors of Acute Lymphoblastic Leukemia",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Lymphoblastic Leukemia"
      ],
      "interventions": [
        {
          "name": "Family-based Behavioral Weight Loss Treatment",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "5 Years and older"
      },
      "enrollment_count": 17,
      "start_date": "2022-07-22",
      "completion_date": "2024-03-26",
      "has_results": false,
      "last_update_posted_date": "2024-05-03",
      "last_synced_at": "2026-09-17T01:10:44.609Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05410574"
    },
    {
      "nct_id": "NCT02497859",
      "title": "Breakfast Intake and Satiety Hormones",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Egg Breakfast (EB)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cereal Breakfast (CB)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Weight Loss Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Weight Loss Diet",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Texas Tech University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "44 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 44 Years · Female only"
      },
      "enrollment_count": 20,
      "start_date": "2015-09",
      "completion_date": "2016-05",
      "has_results": false,
      "last_update_posted_date": "2016-09-16",
      "last_synced_at": "2026-09-17T01:10:44.609Z",
      "location_count": 1,
      "location_summary": "Lubbock, Texas",
      "locations": [
        {
          "city": "Lubbock",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02497859"
    }
  ]
}