{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Reference+Dentifrice+%28Colgate+Cavity+Protection+Dentifrice%29", "query": { "intervention": "Reference Dentifrice (Colgate Cavity Protection Dentifrice)" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 8, "total_pages": 1, "next_page_url": null, "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-29T04:03:14.128Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04696536", "title": "A Twelve Week Study of Supervised Mouth Rinse and Flossing", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Healthy" ], "interventions": [ { "name": "Colgate Cavity Protection Toothpaste", "type": "OTHER" }, { "name": "American Dental Association (ADA) Referenced Toothbrush", "type": "OTHER" }, { "name": "5% Hydroalcohol Mouth Rinse", "type": "OTHER" }, { "name": "REACH Dental Floss", "type": "OTHER" }, { "name": "Alcohol-containing Essential Oil (AEO) Mouth Rinse (Listerine Cool Mint, marketed)", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Johnson & Johnson Consumer Inc. (J&JCI)", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 149, "start_date": "2018-09-26", "completion_date": "2018-12-21", "has_results": false, "last_update_posted_date": "2021-09-28", "last_synced_at": "2026-09-29T04:03:14.128Z", "location_count": 1, "location_summary": "Fort Wayne, Indiana", "locations": [ { "city": "Fort Wayne", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT04696536" }, { "nct_id": "NCT05600231", "title": "A Study of Virtually Supervised Mouth Rinses and Flossing", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Healthy" ], "interventions": [ { "name": "LISTERINE COOL MINT Antiseptic Mouthwash", "type": "OTHER" }, { "name": "LISTERINE COOL MINT ZERO Alcohol Mouthwash", "type": "OTHER" }, { "name": "Reach Unflavored Waxed Dental Floss", "type": "OTHER" }, { "name": "Colgate Cavity Protection Toothpaste", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Johnson & Johnson Consumer Inc. (J&JCI)", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 284, "start_date": "2022-04-18", "completion_date": "2022-07-25", "has_results": false, "last_update_posted_date": "2023-06-18", "last_synced_at": "2026-09-29T04:03:14.128Z", "location_count": 1, "location_summary": "Fort Wayne, Indiana", "locations": [ { "city": "Fort Wayne", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT05600231" }, { "nct_id": "NCT07704905", "title": "A Study to Investigate the Efficacy of an Experimental Dentifrice Containing Stannous Fluoride in Improving Gingival Health", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Dental Plaque", "Gingivitis" ], "interventions": [ { "name": "Test Dentifrice", "type": "DRUG" }, { "name": "Reference Dentifrice (Colgate Cavity Protection Dentifrice)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "HALEON", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 110, "start_date": "2026-07-13", "completion_date": "2026-10", "has_results": false, "last_update_posted_date": "2026-08-12", "last_synced_at": "2026-09-29T04:03:14.128Z", "location_count": 1, "location_summary": "Fort Wayne, Indiana", "locations": [ { "city": "Fort Wayne", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT07704905" }, { "nct_id": "NCT07255040", "title": "A Clinical Study to Evaluate the Effectiveness of an Experimental Toothpaste in Improving Gum Health and Reducing Plaque Accumulation", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Dental Plaque", "Gingivitis" ], "interventions": [ { "name": "Test Dentifrice", "type": "DRUG" }, { "name": "Parodontax Complete Protection", "type": "DRUG" }, { "name": "Colgate Cavity Protection", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "HALEON", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 284, "start_date": "2025-11-19", "completion_date": "2026-07-30", "has_results": false, "last_update_posted_date": "2026-08-05", "last_synced_at": "2026-09-29T04:03:14.128Z", "location_count": 1, "location_summary": "Fort Wayne, Indiana", "locations": [ { "city": "Fort Wayne", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT07255040" }, { "nct_id": "NCT06150573", "title": "A Study Assessing the Effects of an Experimental Dentifrice in Maintaining Tooth Color Following Tooth Bleaching", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Dentin Sensitivity", "Oral Hygiene" ], "interventions": [ { "name": "Test Dentifrice", "type": "DRUG" }, { "name": "Reference Dentifrice (Aquafresh Cavity Protection)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "HALEON", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 160, "start_date": "2023-11-27", "completion_date": "2024-07-18", "has_results": true, "last_update_posted_date": "2025-07-24", "last_synced_at": "2026-09-29T04:03:14.128Z", "location_count": 1, "location_summary": "Las Vegas, Nevada", "locations": [ { "city": "Las Vegas", "state": "Nevada" } ], "official_url": "https://clinicaltrials.gov/study/NCT06150573" }, { "nct_id": "NCT04921371", "title": "Six Week Study of Experimental Mouth Rinses: Effect on Gingivitis and Plaque", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Gingivitis", "Plaque" ], "interventions": [ { "name": "Colgate® Cavity Protection Toothpaste", "type": "OTHER" }, { "name": "Listerine® Cool Mint®", "type": "OTHER" }, { "name": "Concept Curve Winter Series Toothbrush", "type": "OTHER" }, { "name": "5% Hydroalcohol Mouthrinse", "type": "OTHER" }, { "name": "Mouthrinse Prototype 1", "type": "OTHER" }, { "name": "Mouthrinse Prototype 2", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Johnson & Johnson Consumer Inc. (J&JCI)", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 157, "start_date": "2019-10-08", "completion_date": "2019-12-19", "has_results": false, "last_update_posted_date": "2023-09-28", "last_synced_at": "2026-09-29T04:03:14.128Z", "location_count": 1, "location_summary": "Fort Wayne, Indiana", "locations": [ { "city": "Fort Wayne", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT04921371" }, { "nct_id": "NCT06048809", "title": "A Study to Evaluate the Effect of a Stannous Fluoride Toothpaste on the Oral Microbiome", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Oral Health" ], "interventions": [ { "name": "Stannous Fluoride Toothpaste (Sensodyne Repair and Protect)", "type": "OTHER" }, { "name": "Regular Fluoride Toothpaste (Colgate Cavity Protection)", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "HALEON", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 56, "start_date": "2024-04-10", "completion_date": "2024-05-30", "has_results": true, "last_update_posted_date": "2025-07-10", "last_synced_at": "2026-09-29T04:03:14.128Z", "location_count": 1, "location_summary": "Fort Wayne, Indiana", "locations": [ { "city": "Fort Wayne", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT06048809" }, { "nct_id": "NCT06660069", "title": "A Study to Evaluate the Efficacy of a Stannous Fluoride Toothpaste With a Cetylpyridinium Chloride Mouthwash in Improving Gingival Health and Reducing Plaque Accumulation", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Dental Plaque", "Gingivitis" ], "interventions": [ { "name": "Stannous Fluoride Toothpaste (Parodontax Complete Protection Toothpaste)", "type": "DRUG" }, { "name": "CPC Mouthwash (Parodontax Active Gum Health Mouthwash)", "type": "DRUG" }, { "name": "Regular Fluoride Toothpaste (Crest Cavity Protection)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "HALEON", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 199, "start_date": "2024-11-18", "completion_date": "2025-03-11", "has_results": true, "last_update_posted_date": "2026-03-18", "last_synced_at": "2026-09-29T04:03:14.128Z", "location_count": 1, "location_summary": "Fort Wayne, Indiana", "locations": [ { "city": "Fort Wayne", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT06660069" } ] }