{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Reference+examination&page=6",
    "query": {
      "intervention": "Reference examination",
      "page": 6
    },
    "page_size": 10
  },
  "pagination": {
    "page": 6,
    "page_size": 10,
    "total_count": 153,
    "total_pages": 16,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Reference+examination&page=7&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Reference+examination&page=5&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-22T18:18:44.926Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04921371",
      "title": "Six Week Study of Experimental Mouth Rinses: Effect on Gingivitis and Plaque",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Gingivitis",
        "Plaque"
      ],
      "interventions": [
        {
          "name": "Colgate® Cavity Protection Toothpaste",
          "type": "OTHER"
        },
        {
          "name": "Listerine® Cool Mint®",
          "type": "OTHER"
        },
        {
          "name": "Concept Curve Winter Series Toothbrush",
          "type": "OTHER"
        },
        {
          "name": "5% Hydroalcohol Mouthrinse",
          "type": "OTHER"
        },
        {
          "name": "Mouthrinse Prototype 1",
          "type": "OTHER"
        },
        {
          "name": "Mouthrinse Prototype 2",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Johnson & Johnson Consumer Inc. (J&JCI)",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 157,
      "start_date": "2019-10-08",
      "completion_date": "2019-12-19",
      "has_results": false,
      "last_update_posted_date": "2023-09-28",
      "last_synced_at": "2026-10-22T18:18:44.926Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04921371"
    },
    {
      "nct_id": "NCT07345130",
      "title": "A Bioequivalence Study of Advil Tablet (Mini) (Ibuprofen 200 mg) Versus Advil Tablet (Ibuprofen 200 mg) in Healthy Adult Subjects Under Fasted Conditions and Bioavailability Assessment of Advil Tablet (Mini) Under Fed Conditions",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Bioequivalence",
        "Bioavailability"
      ],
      "interventions": [
        {
          "name": "Advil Tablet (Mini) (Test Product)",
          "type": "DRUG"
        },
        {
          "name": "Advil Tablet (Reference Product)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "HALEON",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 68,
      "start_date": "2025-12-17",
      "completion_date": "2026-02-03",
      "has_results": false,
      "last_update_posted_date": "2026-09-23",
      "last_synced_at": "2026-10-22T18:18:44.926Z",
      "location_count": 1,
      "location_summary": "Las Vegas, Nevada",
      "locations": [
        {
          "city": "Las Vegas",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07345130"
    },
    {
      "nct_id": "NCT02693275",
      "title": "Reference Database Development for the Quotient® System iPad Test",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy Volunteers"
      ],
      "interventions": [
        {
          "name": "Quotient® System iPad Test",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Pearson/Clinical Assessment",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "6 Years to 80 Years"
      },
      "enrollment_count": 1333,
      "start_date": "2016-04",
      "completion_date": "2017-03-31",
      "has_results": false,
      "last_update_posted_date": "2017-04-05",
      "last_synced_at": "2026-10-22T18:18:44.926Z",
      "location_count": 4,
      "location_summary": "Las Vegas, Nevada • Raleigh, North Carolina • Clinton, Utah + 1 more",
      "locations": [
        {
          "city": "Las Vegas",
          "state": "Nevada"
        },
        {
          "city": "Raleigh",
          "state": "North Carolina"
        },
        {
          "city": "Clinton",
          "state": "Utah"
        },
        {
          "city": "Layton",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02693275"
    },
    {
      "nct_id": "NCT03716349",
      "title": "Esthetics of Dental Composite and Adhesive System",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cavities of Teeth"
      ],
      "interventions": [
        {
          "name": "Pulp vitality testing",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Photos",
          "type": "OTHER"
        },
        {
          "name": "local and/or topical anesthetic",
          "type": "DRUG"
        },
        {
          "name": "rubber dam",
          "type": "DEVICE"
        },
        {
          "name": "tooth surface cleaned",
          "type": "OTHER"
        },
        {
          "name": "enamel margins",
          "type": "PROCEDURE"
        },
        {
          "name": "Adhesive Systems",
          "type": "PROCEDURE"
        },
        {
          "name": "cavity preparation",
          "type": "PROCEDURE"
        },
        {
          "name": "Shade selection using Easy Shade 5",
          "type": "OTHER"
        },
        {
          "name": "Light Curing",
          "type": "PROCEDURE"
        },
        {
          "name": "Contoured and polished",
          "type": "PROCEDURE"
        },
        {
          "name": "Consent",
          "type": "OTHER"
        },
        {
          "name": "Health Questionnaire",
          "type": "OTHER"
        },
        {
          "name": "xray",
          "type": "RADIATION"
        },
        {
          "name": "Release of medical information signed",
          "type": "OTHER"
        },
        {
          "name": "Oral Exam",
          "type": "OTHER"
        },
        {
          "name": "Teeth Assessment",
          "type": "OTHER"
        },
        {
          "name": "Clinical Assessment",
          "type": "OTHER"
        },
        {
          "name": "Tokuyama Universal Bond",
          "type": "DEVICE"
        },
        {
          "name": "ScotchBond",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "OTHER",
        "DRUG",
        "DEVICE",
        "PROCEDURE",
        "RADIATION"
      ],
      "sponsor": "Erica Teixeira",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 36,
      "start_date": "2019-01-01",
      "completion_date": "2025-11-20",
      "has_results": true,
      "last_update_posted_date": "2026-05-01",
      "last_synced_at": "2026-10-22T18:18:44.926Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03716349"
    },
    {
      "nct_id": "NCT06921993",
      "title": "Lung Ultrasound for Guiding Antibiotic Use in Pediatric Pneumonia",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pneumonia Childhood",
        "Pneumonia",
        "Lung Ultrasound",
        "Antibiotic Stewardship"
      ],
      "interventions": [
        {
          "name": "LUNG ULTRASOUND",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Meyer Children's Hospital IRCCS",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "10 Years",
        "sex": "ALL",
        "summary": "3 Years to 10 Years"
      },
      "enrollment_count": 659,
      "start_date": "2025-04-24",
      "completion_date": "2028-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-04-03",
      "last_synced_at": "2026-10-22T18:18:44.926Z",
      "location_count": 4,
      "location_summary": "San Diego, California • New Haven, Connecticut • New York, New York + 1 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06921993"
    },
    {
      "nct_id": "NCT04852601",
      "title": "ToolBox Detect: Low Cost Detection of Cognitive Decline in Primary Care Settings",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cognitive Dysfunction",
        "Dementia"
      ],
      "interventions": [
        {
          "name": "ToolboxDetect",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 35403,
      "start_date": "2022-08-25",
      "completion_date": "2026-05-31",
      "has_results": false,
      "last_update_posted_date": "2026-08-25",
      "last_synced_at": "2026-10-22T18:18:44.926Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04852601"
    },
    {
      "nct_id": "NCT04169802",
      "title": "Study Evaluating Retinal Health Monitoring System Visual Acuity Module.",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Age Related Macular Degeneration"
      ],
      "interventions": [
        {
          "name": "Retinal Health Monitoring System Visual Acuity Module",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Sloan letter, logarithmic near visual acuity chart (Reference Chart)",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Kubota Vision Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 25,
      "start_date": "2019-11-20",
      "completion_date": "2020-04-15",
      "has_results": false,
      "last_update_posted_date": "2021-02-21",
      "last_synced_at": "2026-10-22T18:18:44.926Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04169802"
    },
    {
      "nct_id": "NCT07280065",
      "title": "REVEAL Study - Diagnostic Testing for PTSD Using the Senseye Diagnostic Tool",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "PTSD - Post Traumatic Stress Disorder"
      ],
      "interventions": [
        {
          "name": "Senseye Diagnostic Tool (DT)",
          "type": "DEVICE"
        },
        {
          "name": "Clinician Administered PTSD Scale for DSM-5, Revised Version",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "Senseye, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1900,
      "start_date": "2026-02-23",
      "completion_date": "2026-10",
      "has_results": false,
      "last_update_posted_date": "2026-04-29",
      "last_synced_at": "2026-10-22T18:18:44.926Z",
      "location_count": 5,
      "location_summary": "Aurora, Colorado • Savannah, Georgia • Meridian, Idaho + 2 more",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Savannah",
          "state": "Georgia"
        },
        {
          "city": "Meridian",
          "state": "Idaho"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07280065"
    },
    {
      "nct_id": "NCT07200232",
      "title": "A Three-phase Study That Will Compare the ECG Data Recorded Using the Test Device With the Data Recorded by a Reference Device, Evaluate the ECG Signal Quality of the Test Device Over a 10-day Simulated Use Period, and Assess the Effects of Variable ECG Electrode Placement for the Test Device",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy Subjects"
      ],
      "interventions": [
        {
          "name": "Phase 1 Test Device Sensor and Adhesive and Reference Device",
          "type": "DEVICE"
        },
        {
          "name": "Phase 2 Test Device ECG Signal quality over a 10-day simulated use period",
          "type": "DEVICE"
        },
        {
          "name": "Test Device Sensor and Adhesive Variable Placement",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Zywie, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 45,
      "start_date": "2025-01-15",
      "completion_date": "2025-02-14",
      "has_results": false,
      "last_update_posted_date": "2025-10-01",
      "last_synced_at": "2026-10-22T18:18:44.926Z",
      "location_count": 1,
      "location_summary": "Bozeman, Montana",
      "locations": [
        {
          "city": "Bozeman",
          "state": "Montana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07200232"
    },
    {
      "nct_id": "NCT03474432",
      "title": "SOLEMN Study - Synergy Optical Coherence Tomography in Left Main PCI",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Percutaneous Coronary Intervention",
        "Optical Coherence Tomography",
        "In-stent Coronary Artery Restenosis"
      ],
      "interventions": [
        {
          "name": "Optical Coherence Tomography",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Jesse Brown VA Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 12,
      "start_date": "2018-07-11",
      "completion_date": "2020-05-31",
      "has_results": true,
      "last_update_posted_date": "2024-05-17",
      "last_synced_at": "2026-10-22T18:18:44.926Z",
      "location_count": 13,
      "location_summary": "Birmingham, Alabama • Tucson, Arizona • Long Beach, California + 10 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Long Beach",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03474432"
    }
  ]
}