{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Refined+Grains",
    "query": {
      "intervention": "Refined Grains"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 47,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Refined+Grains&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-03T09:02:01.559Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00123526",
      "title": "Workplace-Sponsored Diet and Exercise Program to Reduce Obesity",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Obesity",
        "Cardiovascular Diseases",
        "Heart Diseases"
      ],
      "interventions": [
        {
          "name": "Diet",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Physical Activity",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Massachusetts, Worcester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 899,
      "start_date": "2004-09",
      "completion_date": "2008-06",
      "has_results": false,
      "last_update_posted_date": "2013-09-24",
      "last_synced_at": "2026-09-03T09:02:01.559Z",
      "location_count": 1,
      "location_summary": "Worcester, Massachusetts",
      "locations": [
        {
          "city": "Worcester",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00123526"
    },
    {
      "nct_id": "NCT05990439",
      "title": "Baby-Feed Web Application for Infant Caregivers to Improve Diets and Weight Gain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity, Childhood"
      ],
      "interventions": [
        {
          "name": "Baby-Feed",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Limited access to the Baby-Feed web application",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Florida International University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "1 Month",
        "maximum_age": "3 Months",
        "sex": "ALL",
        "summary": "1 Month to 3 Months"
      },
      "enrollment_count": 155,
      "start_date": "2024-04-01",
      "completion_date": "2025-08-01",
      "has_results": false,
      "last_update_posted_date": "2025-09-12",
      "last_synced_at": "2026-09-03T09:02:01.559Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05990439"
    },
    {
      "nct_id": "NCT07767162",
      "title": "Pharmacokinetic (PK) Study of Phytochemicals in Whole Grains (WGs)- Corn",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy Adult Females",
        "Healthy Adult Males"
      ],
      "interventions": [
        {
          "name": "Whole-Grain Corn",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Refined Corn",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "North Carolina Agriculture & Technical State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "25 Years to 70 Years"
      },
      "enrollment_count": 16,
      "start_date": "2026-08-04",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-08-24",
      "last_synced_at": "2026-09-03T09:02:01.559Z",
      "location_count": 1,
      "location_summary": "Kannapolis, North Carolina",
      "locations": [
        {
          "city": "Kannapolis",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07767162"
    },
    {
      "nct_id": "NCT07167004",
      "title": "The GRoceries Aimed at Increasing Nutrition Study",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Type 2 Diabetes",
        "Type II Diabetes Mellitus",
        "Type II Diabetes",
        "Pre-diabetes",
        "Pre-diabetic",
        "Pre-diabetic State",
        "Type 2 Diabetes Mellitus (T2DM)",
        "Type 2 Diabetes Mellitus",
        "Type 2 Diabetes (T2DM)"
      ],
      "interventions": [
        {
          "name": "Marketing Nudges Only",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Marketing Nudges + Dynamically Adapted Financial Incentives",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "45 Years to 70 Years"
      },
      "enrollment_count": 216,
      "start_date": "2025-10-14",
      "completion_date": "2027-02-16",
      "has_results": false,
      "last_update_posted_date": "2026-08-06",
      "last_synced_at": "2026-09-03T09:02:01.559Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07167004"
    },
    {
      "nct_id": "NCT02800408",
      "title": "Comparison of Beta-cryptoxanthin Bioavailability From Biofortified Maize in Humans",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "β-cryptoxanthin Bioavailability From Biofortified Maize in Humans"
      ],
      "interventions": [
        {
          "name": "Whole grain high-BCX maize",
          "type": "OTHER"
        },
        {
          "name": "Refined grain high-BCX maize",
          "type": "OTHER"
        },
        {
          "name": "Whole grain white maize",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "28 Years",
        "sex": "ALL",
        "summary": "20 Years to 28 Years"
      },
      "enrollment_count": 10,
      "start_date": "2016-07-21",
      "completion_date": "2017-10-23",
      "has_results": false,
      "last_update_posted_date": "2019-01-24",
      "last_synced_at": "2026-09-03T09:02:01.559Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02800408"
    },
    {
      "nct_id": "NCT05621863",
      "title": "Fruit and Vegetable Biomarker Discovery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Biomarkers"
      ],
      "interventions": [
        {
          "name": "Aim 1 Meal Challenge 1",
          "type": "OTHER"
        },
        {
          "name": "Aim 1 Meal Challenge 2",
          "type": "OTHER"
        },
        {
          "name": "Aim 1 Meal Challenge 3",
          "type": "OTHER"
        },
        {
          "name": "Aim 2 Typical American Diet",
          "type": "OTHER"
        },
        {
          "name": "Aim 2 Typical American Diet Plus Test Foods",
          "type": "OTHER"
        },
        {
          "name": "Aim 2 Dietary Guidelines for Americans Diet Plus Test Foods",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2023-04-01",
      "completion_date": "2026-03-13",
      "has_results": false,
      "last_update_posted_date": "2026-05-29",
      "last_synced_at": "2026-09-03T09:02:01.559Z",
      "location_count": 1,
      "location_summary": "Davis, California",
      "locations": [
        {
          "city": "Davis",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05621863"
    },
    {
      "nct_id": "NCT05500976",
      "title": "Metabolomics Initiative: Mediterranean-amplified vs Habitual Western Diet on Food Signatures, Health, and Microbiome",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dietary Habits"
      ],
      "interventions": [
        {
          "name": "Semi-controlled dietary intervention - Western",
          "type": "OTHER"
        },
        {
          "name": "Semi-controlled dietary intervention - MiniMed",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "69 Years",
        "sex": "ALL",
        "summary": "30 Years to 69 Years"
      },
      "enrollment_count": 22,
      "start_date": "2022-11-21",
      "completion_date": "2025-03-31",
      "has_results": false,
      "last_update_posted_date": "2024-08-27",
      "last_synced_at": "2026-09-03T09:02:01.559Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05500976"
    },
    {
      "nct_id": "NCT01403857",
      "title": "Evaluating Liking, Acceptability and Health Benefits of Grain Products",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Food Preferences"
      ],
      "interventions": [
        {
          "name": "Whole grain foods",
          "type": "OTHER"
        },
        {
          "name": "Refined grains",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "USDA, Western Human Nutrition Research Center",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "20 Years to 45 Years"
      },
      "enrollment_count": 45,
      "start_date": "2010-04",
      "completion_date": "2013-12",
      "has_results": false,
      "last_update_posted_date": "2024-03-12",
      "last_synced_at": "2026-09-03T09:02:01.559Z",
      "location_count": 1,
      "location_summary": "Davis, California",
      "locations": [
        {
          "city": "Davis",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01403857"
    },
    {
      "nct_id": "NCT01610661",
      "title": "Dietary Carbohydrate Type and Cardiovascular Disease (CVD) Risk Indicators",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dyslipidemia"
      ],
      "interventions": [
        {
          "name": "Diet",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Tufts University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2012-01",
      "completion_date": "2017-12",
      "has_results": false,
      "last_update_posted_date": "2018-07-13",
      "last_synced_at": "2026-09-03T09:02:01.559Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01610661"
    },
    {
      "nct_id": "NCT03810378",
      "title": "Contrasting Ketogenic and Mediterranean Diets in Individuals With Type 2 Diabetes and Prediabetes: The Keto-Med Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes Mellitus, Type 2",
        "PreDiabetes"
      ],
      "interventions": [
        {
          "name": "Mediterranean Diet (Med-Plus)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Well-Formulated Ketogenic Diet (WFKD)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 61,
      "start_date": "2019-06-05",
      "completion_date": "2020-12-06",
      "has_results": false,
      "last_update_posted_date": "2023-02-21",
      "last_synced_at": "2026-09-03T09:02:01.559Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03810378"
    }
  ]
}