{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Refined+Grains&page=2",
    "query": {
      "intervention": "Refined Grains",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Refined+Grains&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-28T06:46:21.638Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06386471",
      "title": "Personalized GI Motility Responses to Diet",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nutritional and Metabolic Diseases",
        "Gastrointestinal Dysfunction",
        "Cardiovascular Diseases",
        "Dysbiosis"
      ],
      "interventions": [
        {
          "name": "Whole grain rye bread",
          "type": "OTHER"
        },
        {
          "name": "Refined grain rye bread",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Illinois at Urbana-Champaign",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "63 Years",
        "sex": "ALL",
        "summary": "21 Years to 63 Years"
      },
      "enrollment_count": 50,
      "start_date": "2024-03-07",
      "completion_date": "2025-06-02",
      "has_results": false,
      "last_update_posted_date": "2024-04-26",
      "last_synced_at": "2026-09-28T06:46:21.638Z",
      "location_count": 1,
      "location_summary": "Urbana, Illinois",
      "locations": [
        {
          "city": "Urbana",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06386471"
    },
    {
      "nct_id": "NCT00924521",
      "title": "Grains Reduce Adiposity and Improve Nutrition Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Metabolic Syndrome",
        "Insulin Resistance"
      ],
      "interventions": [
        {
          "name": "Whole grain diet",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Refined grain",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Penn State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "35 Years to 55 Years"
      },
      "enrollment_count": 54,
      "start_date": "2009-03",
      "completion_date": "2011-08",
      "has_results": false,
      "last_update_posted_date": "2023-08-21",
      "last_synced_at": "2026-09-28T06:46:21.638Z",
      "location_count": 1,
      "location_summary": "University Park, Pennsylvania",
      "locations": [
        {
          "city": "University Park",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00924521"
    },
    {
      "nct_id": "NCT07767162",
      "title": "Pharmacokinetic (PK) Study of Phytochemicals in Whole Grains (WGs)- Corn",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy Adult Females",
        "Healthy Adult Males"
      ],
      "interventions": [
        {
          "name": "Whole-Grain Corn",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Refined Corn",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "North Carolina Agriculture & Technical State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "25 Years to 70 Years"
      },
      "enrollment_count": 16,
      "start_date": "2026-08-04",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-08-24",
      "last_synced_at": "2026-09-28T06:46:21.638Z",
      "location_count": 1,
      "location_summary": "Kannapolis, North Carolina",
      "locations": [
        {
          "city": "Kannapolis",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07767162"
    },
    {
      "nct_id": "NCT07167004",
      "title": "The GRoceries Aimed at Increasing Nutrition Study",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Type 2 Diabetes",
        "Type II Diabetes Mellitus",
        "Type II Diabetes",
        "Pre-diabetes",
        "Pre-diabetic",
        "Pre-diabetic State",
        "Type 2 Diabetes Mellitus (T2DM)",
        "Type 2 Diabetes Mellitus",
        "Type 2 Diabetes (T2DM)"
      ],
      "interventions": [
        {
          "name": "Marketing Nudges Only",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Marketing Nudges + Dynamically Adapted Financial Incentives",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "45 Years to 70 Years"
      },
      "enrollment_count": 216,
      "start_date": "2025-10-14",
      "completion_date": "2027-02-16",
      "has_results": false,
      "last_update_posted_date": "2026-08-06",
      "last_synced_at": "2026-09-28T06:46:21.638Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07167004"
    },
    {
      "nct_id": "NCT01248286",
      "title": "Effect of Whole Grain Diet on Insulin Sensitivity, Advanced Glycation End Products and Inflammatory Markers in Pre-diabetes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes",
        "Prediabetes"
      ],
      "interventions": [
        {
          "name": "Whole grain rice",
          "type": "OTHER"
        },
        {
          "name": "Refined grain rice",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Icahn School of Medicine at Mount Sinai",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2010-11",
      "completion_date": "2011-04",
      "has_results": false,
      "last_update_posted_date": "2013-10-22",
      "last_synced_at": "2026-09-28T06:46:21.638Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01248286"
    },
    {
      "nct_id": "NCT03925142",
      "title": "Effects of Replacing Starchy Vegetables and Refined Grains With Beef on Cardio-metabolic Disease Risk Factors (S53)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diet Modification"
      ],
      "interventions": [
        {
          "name": "Controlled healthy vegetarian diet",
          "type": "OTHER"
        },
        {
          "name": "Controlled beef diet",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Purdue University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "69 Years",
        "sex": "ALL",
        "summary": "30 Years to 69 Years"
      },
      "enrollment_count": 43,
      "start_date": "2019-06-04",
      "completion_date": "2021-10-28",
      "has_results": false,
      "last_update_posted_date": "2021-12-08",
      "last_synced_at": "2026-09-28T06:46:21.638Z",
      "location_count": 1,
      "location_summary": "West Lafayette, Indiana",
      "locations": [
        {
          "city": "West Lafayette",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03925142"
    },
    {
      "nct_id": "NCT04104581",
      "title": "Measuring Daily Grain Intake Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy Volunteers"
      ],
      "interventions": [
        {
          "name": "Control Refined Grain Diet",
          "type": "OTHER"
        },
        {
          "name": "Low Whole Grain Oat Diet",
          "type": "OTHER"
        },
        {
          "name": "High Whole Grain Oat Diet",
          "type": "OTHER"
        },
        {
          "name": "Low Whole Grain Wheat Diet",
          "type": "OTHER"
        },
        {
          "name": "High Whole Grain Wheat Diet",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "USDA Beltsville Human Nutrition Research Center",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "21 Years to 75 Years"
      },
      "enrollment_count": 57,
      "start_date": "2019-08-04",
      "completion_date": "2020-03-16",
      "has_results": false,
      "last_update_posted_date": "2020-05-11",
      "last_synced_at": "2026-09-28T06:46:21.638Z",
      "location_count": 1,
      "location_summary": "Beltsville, Maryland",
      "locations": [
        {
          "city": "Beltsville",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04104581"
    },
    {
      "nct_id": "NCT03430141",
      "title": "A Nutritarian Study to Evaluate the Effectiveness of Lifestyle Changes in Chronic Disease Prevention, Especially Cancer",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Disease",
        "Cancer",
        "Cardiovascular Diseases",
        "Diabetes Mellitus",
        "Lifestyle-related Condition",
        "Mental Health Wellness 1",
        "Sleep",
        "Nutritional and Metabolic Disease",
        "Nutrition Related Cancer",
        "Nutritional Imbalance",
        "Thyroid"
      ],
      "interventions": [
        {
          "name": "Nutritarian Diet-style",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Northern Arizona University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 2898,
      "start_date": "2016-10-31",
      "completion_date": "2019-12-31",
      "has_results": false,
      "last_update_posted_date": "2020-09-22",
      "last_synced_at": "2026-09-28T06:46:21.638Z",
      "location_count": 1,
      "location_summary": "Flagstaff, Arizona",
      "locations": [
        {
          "city": "Flagstaff",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03430141"
    },
    {
      "nct_id": "NCT04511325",
      "title": "Effects of White Potato Consumption on Measures of Cardiometabolic Health in Individuals With Type 2 Diabetes Mellitus",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Type2 Diabetes",
        "Cardiometabolic Syndrome",
        "Arterial Stiffness",
        "Overweight and Obesity"
      ],
      "interventions": [
        {
          "name": "Potato Regimen",
          "type": "OTHER"
        },
        {
          "name": "Refined Grain Regimen",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Florida State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "45 Years to 80 Years"
      },
      "enrollment_count": 27,
      "start_date": "2019-04-27",
      "completion_date": "2022-05-20",
      "has_results": false,
      "last_update_posted_date": "2022-09-08",
      "last_synced_at": "2026-09-28T06:46:21.638Z",
      "location_count": 1,
      "location_summary": "Tallahassee, Florida",
      "locations": [
        {
          "city": "Tallahassee",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04511325"
    },
    {
      "nct_id": "NCT05411120",
      "title": "Mediterranean-like Unprocessed (CLEAN-MED) Diet Intervention Study of the Gut Microbiome of Healthy Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diet Therapy"
      ],
      "interventions": [
        {
          "name": "Western Diet",
          "type": "OTHER"
        },
        {
          "name": "CLEAN-MED",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "National Institutes of Health Clinical Center (CC)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 160,
      "start_date": "2022-08-26",
      "completion_date": "2026-02-05",
      "has_results": false,
      "last_update_posted_date": "2026-03-06",
      "last_synced_at": "2026-09-28T06:46:21.638Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05411120"
    }
  ]
}