{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Refined+grain&page=2",
    "query": {
      "intervention": "Refined grain",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 49,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Refined+grain&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Refined+grain&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-30T14:10:29.187Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02602496",
      "title": "Promoting Gastrointestinal Health and Reducing Subclinical Inflammation in Obese Individuals",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Overweight"
      ],
      "interventions": [
        {
          "name": "Fruits and Vegetables",
          "type": "OTHER"
        },
        {
          "name": "Whole Grain",
          "type": "OTHER"
        },
        {
          "name": "Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Nebraska Lincoln",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 52,
      "start_date": "2015-10",
      "completion_date": "2017-07",
      "has_results": true,
      "last_update_posted_date": "2019-06-05",
      "last_synced_at": "2026-09-30T14:10:29.187Z",
      "location_count": 1,
      "location_summary": "Lincoln, Nebraska",
      "locations": [
        {
          "city": "Lincoln",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02602496"
    },
    {
      "nct_id": "NCT04606420",
      "title": "Can Lifestyle Changes Reverse Early-Stage Alzheimer's Disease",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alzheimer Disease"
      ],
      "interventions": [
        {
          "name": "Lifestyle medicine",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Preventive Medicine Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "45 Years to 90 Years"
      },
      "enrollment_count": 51,
      "start_date": "2018-09-08",
      "completion_date": "2023-09-30",
      "has_results": false,
      "last_update_posted_date": "2022-09-15",
      "last_synced_at": "2026-09-30T14:10:29.187Z",
      "location_count": 4,
      "location_summary": "San Diego, California • Sausalito, California • Boston, Massachusetts + 1 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Sausalito",
          "state": "California"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Reno",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04606420"
    },
    {
      "nct_id": "NCT04511325",
      "title": "Effects of White Potato Consumption on Measures of Cardiometabolic Health in Individuals With Type 2 Diabetes Mellitus",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Type2 Diabetes",
        "Cardiometabolic Syndrome",
        "Arterial Stiffness",
        "Overweight and Obesity"
      ],
      "interventions": [
        {
          "name": "Potato Regimen",
          "type": "OTHER"
        },
        {
          "name": "Refined Grain Regimen",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Florida State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "45 Years to 80 Years"
      },
      "enrollment_count": 27,
      "start_date": "2019-04-27",
      "completion_date": "2022-05-20",
      "has_results": false,
      "last_update_posted_date": "2022-09-08",
      "last_synced_at": "2026-09-30T14:10:29.187Z",
      "location_count": 1,
      "location_summary": "Tallahassee, Florida",
      "locations": [
        {
          "city": "Tallahassee",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04511325"
    },
    {
      "nct_id": "NCT00422630",
      "title": "The Metabolic Effects of Different Weight Loss Diets",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Metabolic Syndrome X",
        "Obesity",
        "Insulin Resistance",
        "Hypertension",
        "Diabetes"
      ],
      "interventions": [
        {
          "name": "The DASH diet",
          "type": "BEHAVIORAL"
        },
        {
          "name": "The low glycemic Index Diet",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Reduced calorie American Diet",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Rockefeller University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 18,
      "start_date": "2007-10",
      "completion_date": "2010-02",
      "has_results": false,
      "last_update_posted_date": "2011-10-13",
      "last_synced_at": "2026-09-30T14:10:29.187Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00422630"
    },
    {
      "nct_id": "NCT01044134",
      "title": "Think AHEAD (A Healthy Eating And Drinking) Study",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Dietary counseling",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "12 Years to 17 Years"
      },
      "enrollment_count": 38,
      "start_date": "2011-02",
      "completion_date": "2014-06",
      "has_results": false,
      "last_update_posted_date": "2015-07-29",
      "last_synced_at": "2026-09-30T14:10:29.187Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01044134"
    },
    {
      "nct_id": "NCT01411540",
      "title": "Effects of a Wholegrain Diet on Body Composition and Energy Balance",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Overweight",
        "Obesity",
        "Pre-diabetic"
      ],
      "interventions": [
        {
          "name": "Whole grains",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "20 Years to 50 Years"
      },
      "enrollment_count": 35,
      "start_date": "2010-06",
      "completion_date": "2014-12",
      "has_results": false,
      "last_update_posted_date": "2017-01-10",
      "last_synced_at": "2026-09-30T14:10:29.187Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01411540"
    },
    {
      "nct_id": "NCT00123526",
      "title": "Workplace-Sponsored Diet and Exercise Program to Reduce Obesity",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Obesity",
        "Cardiovascular Diseases",
        "Heart Diseases"
      ],
      "interventions": [
        {
          "name": "Diet",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Physical Activity",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Massachusetts, Worcester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 899,
      "start_date": "2004-09",
      "completion_date": "2008-06",
      "has_results": false,
      "last_update_posted_date": "2013-09-24",
      "last_synced_at": "2026-09-30T14:10:29.187Z",
      "location_count": 1,
      "location_summary": "Worcester, Massachusetts",
      "locations": [
        {
          "city": "Worcester",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00123526"
    },
    {
      "nct_id": "NCT06339879",
      "title": "Health Effects of Grain Foods in Adults",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "High Whole Grain and Low Sugar",
        "Medium Whole Grain and Low Sugar",
        "Low Whole Grain and Low Sugar",
        "Low Whole Grain and High Sugar"
      ],
      "interventions": [
        {
          "name": "High Whole Grain, Low Sugar",
          "type": "OTHER"
        },
        {
          "name": "Low Whole Grain, Low Sugar",
          "type": "OTHER"
        },
        {
          "name": "High Whole Grain, High Sugar",
          "type": "OTHER"
        },
        {
          "name": "Low Whole Grain, High Sugar",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Purdue University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "21 Years to 60 Years"
      },
      "enrollment_count": 120,
      "start_date": "2024-01-18",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-07-15",
      "last_synced_at": "2026-09-30T14:10:29.187Z",
      "location_count": 1,
      "location_summary": "West Lafayette, Indiana",
      "locations": [
        {
          "city": "West Lafayette",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06339879"
    },
    {
      "nct_id": "NCT05337150",
      "title": "Remotely Delivered Behavioral Weight Loss Using an Ad Libitum Plant-Based Diet Versus a Balanced Calorie Deficit Diet",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Overweight"
      ],
      "interventions": [
        {
          "name": "Lifestyle Modification Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Balanced Calorie Deficit Eating Plan",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Ad Libitum Whole Food Plant-Based Eating Plan",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Drexel University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 55,
      "start_date": "2022-05-29",
      "completion_date": "2023-03-24",
      "has_results": false,
      "last_update_posted_date": "2023-09-14",
      "last_synced_at": "2026-09-30T14:10:29.187Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05337150"
    },
    {
      "nct_id": "NCT06075914",
      "title": "Ketone Conferred Resiliency Against Sleep Restriction With Nutritional Intervention.",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sleep Deprivation",
        "Nutritional Intervention"
      ],
      "interventions": [
        {
          "name": "Ketogenic Intervention",
          "type": "OTHER"
        },
        {
          "name": "Mediterranean Intervention",
          "type": "OTHER"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Ketone Ester",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 60,
      "start_date": "2023-05-01",
      "completion_date": "2027-02",
      "has_results": false,
      "last_update_posted_date": "2026-06-24",
      "last_synced_at": "2026-09-30T14:10:29.187Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06075914"
    }
  ]
}