{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Refined+grain+diet&page=2",
    "query": {
      "intervention": "Refined grain diet",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 41,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Refined+grain+diet&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Refined+grain+diet&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-04T23:41:15.395Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02800408",
      "title": "Comparison of Beta-cryptoxanthin Bioavailability From Biofortified Maize in Humans",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "β-cryptoxanthin Bioavailability From Biofortified Maize in Humans"
      ],
      "interventions": [
        {
          "name": "Whole grain high-BCX maize",
          "type": "OTHER"
        },
        {
          "name": "Refined grain high-BCX maize",
          "type": "OTHER"
        },
        {
          "name": "Whole grain white maize",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "28 Years",
        "sex": "ALL",
        "summary": "20 Years to 28 Years"
      },
      "enrollment_count": 10,
      "start_date": "2016-07-21",
      "completion_date": "2017-10-23",
      "has_results": false,
      "last_update_posted_date": "2019-01-24",
      "last_synced_at": "2026-10-04T23:41:15.395Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02800408"
    },
    {
      "nct_id": "NCT05337150",
      "title": "Remotely Delivered Behavioral Weight Loss Using an Ad Libitum Plant-Based Diet Versus a Balanced Calorie Deficit Diet",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Overweight"
      ],
      "interventions": [
        {
          "name": "Lifestyle Modification Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Balanced Calorie Deficit Eating Plan",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Ad Libitum Whole Food Plant-Based Eating Plan",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Drexel University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 55,
      "start_date": "2022-05-29",
      "completion_date": "2023-03-24",
      "has_results": false,
      "last_update_posted_date": "2023-09-14",
      "last_synced_at": "2026-10-04T23:41:15.395Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05337150"
    },
    {
      "nct_id": "NCT03925142",
      "title": "Effects of Replacing Starchy Vegetables and Refined Grains With Beef on Cardio-metabolic Disease Risk Factors (S53)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diet Modification"
      ],
      "interventions": [
        {
          "name": "Controlled healthy vegetarian diet",
          "type": "OTHER"
        },
        {
          "name": "Controlled beef diet",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Purdue University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "69 Years",
        "sex": "ALL",
        "summary": "30 Years to 69 Years"
      },
      "enrollment_count": 43,
      "start_date": "2019-06-04",
      "completion_date": "2021-10-28",
      "has_results": false,
      "last_update_posted_date": "2021-12-08",
      "last_synced_at": "2026-10-04T23:41:15.395Z",
      "location_count": 1,
      "location_summary": "West Lafayette, Indiana",
      "locations": [
        {
          "city": "West Lafayette",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03925142"
    },
    {
      "nct_id": "NCT01902394",
      "title": "The Addition of Whole Grains to the Diets of Adults: A Study of Digestive Health and Natural Defenses",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Digestive Health and Immune Function"
      ],
      "interventions": [
        {
          "name": "Whole grains",
          "type": "OTHER"
        },
        {
          "name": "Refined grains",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Tufts University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "40 Years to 65 Years"
      },
      "enrollment_count": 108,
      "start_date": "2012-06",
      "completion_date": "2014-09",
      "has_results": false,
      "last_update_posted_date": "2015-05-21",
      "last_synced_at": "2026-10-04T23:41:15.395Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01902394"
    },
    {
      "nct_id": "NCT05471414",
      "title": "Whole-Food Plant-Based Diet to Control Weight and MetaboInflammation in Overweight/Obese Men With Prostate Cancer",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Prostate Cancer"
      ],
      "interventions": [
        {
          "name": "Whole-food, Plant-Based Diet",
          "type": "BEHAVIORAL"
        },
        {
          "name": "General Nutritional Counseling",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "99 Years",
        "sex": "MALE",
        "summary": "45 Years to 99 Years · Male only"
      },
      "enrollment_count": 76,
      "start_date": "2022-09-22",
      "completion_date": "2027-06",
      "has_results": false,
      "last_update_posted_date": "2026-06-16",
      "last_synced_at": "2026-10-04T23:41:15.395Z",
      "location_count": 3,
      "location_summary": "Baltimore, Maryland • New York, New York",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05471414"
    },
    {
      "nct_id": "NCT02602496",
      "title": "Promoting Gastrointestinal Health and Reducing Subclinical Inflammation in Obese Individuals",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Overweight"
      ],
      "interventions": [
        {
          "name": "Fruits and Vegetables",
          "type": "OTHER"
        },
        {
          "name": "Whole Grain",
          "type": "OTHER"
        },
        {
          "name": "Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Nebraska Lincoln",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 52,
      "start_date": "2015-10",
      "completion_date": "2017-07",
      "has_results": true,
      "last_update_posted_date": "2019-06-05",
      "last_synced_at": "2026-10-04T23:41:15.395Z",
      "location_count": 1,
      "location_summary": "Lincoln, Nebraska",
      "locations": [
        {
          "city": "Lincoln",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02602496"
    },
    {
      "nct_id": "NCT00123526",
      "title": "Workplace-Sponsored Diet and Exercise Program to Reduce Obesity",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Obesity",
        "Cardiovascular Diseases",
        "Heart Diseases"
      ],
      "interventions": [
        {
          "name": "Diet",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Physical Activity",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Massachusetts, Worcester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 899,
      "start_date": "2004-09",
      "completion_date": "2008-06",
      "has_results": false,
      "last_update_posted_date": "2013-09-24",
      "last_synced_at": "2026-10-04T23:41:15.395Z",
      "location_count": 1,
      "location_summary": "Worcester, Massachusetts",
      "locations": [
        {
          "city": "Worcester",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00123526"
    },
    {
      "nct_id": "NCT05621863",
      "title": "Fruit and Vegetable Biomarker Discovery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Biomarkers"
      ],
      "interventions": [
        {
          "name": "Aim 1 Meal Challenge 1",
          "type": "OTHER"
        },
        {
          "name": "Aim 1 Meal Challenge 2",
          "type": "OTHER"
        },
        {
          "name": "Aim 1 Meal Challenge 3",
          "type": "OTHER"
        },
        {
          "name": "Aim 2 Typical American Diet",
          "type": "OTHER"
        },
        {
          "name": "Aim 2 Typical American Diet Plus Test Foods",
          "type": "OTHER"
        },
        {
          "name": "Aim 2 Dietary Guidelines for Americans Diet Plus Test Foods",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2023-04-01",
      "completion_date": "2026-03-13",
      "has_results": false,
      "last_update_posted_date": "2026-05-29",
      "last_synced_at": "2026-10-04T23:41:15.395Z",
      "location_count": 1,
      "location_summary": "Davis, California",
      "locations": [
        {
          "city": "Davis",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05621863"
    },
    {
      "nct_id": "NCT01411540",
      "title": "Effects of a Wholegrain Diet on Body Composition and Energy Balance",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Overweight",
        "Obesity",
        "Pre-diabetic"
      ],
      "interventions": [
        {
          "name": "Whole grains",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "20 Years to 50 Years"
      },
      "enrollment_count": 35,
      "start_date": "2010-06",
      "completion_date": "2014-12",
      "has_results": false,
      "last_update_posted_date": "2017-01-10",
      "last_synced_at": "2026-10-04T23:41:15.395Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01411540"
    },
    {
      "nct_id": "NCT06386471",
      "title": "Personalized GI Motility Responses to Diet",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nutritional and Metabolic Diseases",
        "Gastrointestinal Dysfunction",
        "Cardiovascular Diseases",
        "Dysbiosis"
      ],
      "interventions": [
        {
          "name": "Whole grain rye bread",
          "type": "OTHER"
        },
        {
          "name": "Refined grain rye bread",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Illinois at Urbana-Champaign",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "63 Years",
        "sex": "ALL",
        "summary": "21 Years to 63 Years"
      },
      "enrollment_count": 50,
      "start_date": "2024-03-07",
      "completion_date": "2025-06-02",
      "has_results": false,
      "last_update_posted_date": "2024-04-26",
      "last_synced_at": "2026-10-04T23:41:15.395Z",
      "location_count": 1,
      "location_summary": "Urbana, Illinois",
      "locations": [
        {
          "city": "Urbana",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06386471"
    }
  ]
}