{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Refresh+Liquigel+Lubricant+Eye+Drops",
    "query": {
      "intervention": "Refresh Liquigel Lubricant Eye Drops"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 16,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Refresh+Liquigel+Lubricant+Eye+Drops&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-24T19:29:57.755Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00243711",
      "title": "A Multi-Center Randomized Study to Evaluate the Efficacy and Safety of an Investigational Lubricant Eye Drop",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Dry Eye"
      ],
      "interventions": [
        {
          "name": "Carboxymethylcellulose sodium and Glycerin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Allergan",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 286,
      "start_date": "2005-09",
      "completion_date": "2006-04",
      "has_results": false,
      "last_update_posted_date": "2011-05-30",
      "last_synced_at": "2026-09-24T19:29:57.755Z",
      "location_count": 1,
      "location_summary": "Warrensburg, Missouri",
      "locations": [
        {
          "city": "Warrensburg",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00243711"
    },
    {
      "nct_id": "NCT01010282",
      "title": "Safety and Efficacy of Two Artificial Tears in Dry Eye Subjects",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dry Eye Syndrome"
      ],
      "interventions": [
        {
          "name": "Glycerin and Polysorbate 80 based artificial tear",
          "type": "DRUG"
        },
        {
          "name": "Formulation 1: Carboxymethylcellulose sodium, glycerin and Polysorbate 80, based artificial tear",
          "type": "DRUG"
        },
        {
          "name": "Formulation 2: Carboxymethylcellulose sodium, glycerin, and Polysorbate 80 based artificial tear",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Allergan",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 288,
      "start_date": "2009-11",
      "completion_date": "2010-04",
      "has_results": true,
      "last_update_posted_date": "2015-08-17",
      "last_synced_at": "2026-09-24T19:29:57.755Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01010282"
    },
    {
      "nct_id": "NCT00347854",
      "title": "Fluorophotometry Evaluation of Lubricant Eye Drops",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Systane Free lubricant eye drops",
          "type": "OTHER"
        },
        {
          "name": "Visine Tears Lubricant Eye Drops",
          "type": "OTHER"
        },
        {
          "name": "Refresh Liquigel Lubricant Eye Drops",
          "type": "OTHER"
        },
        {
          "name": "Refresh Plus Lubricant Eye Drops",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2006-04",
      "completion_date": "2006-04",
      "has_results": false,
      "last_update_posted_date": "2016-11-22",
      "last_synced_at": "2026-09-24T19:29:57.755Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00347854"
    },
    {
      "nct_id": "NCT02121847",
      "title": "Investigation of Maintaining Visual Performance Achieved With Cyclosporine Therapy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Dry Eye Syndromes"
      ],
      "interventions": [
        {
          "name": "cyclosporine 0.05% ophthalmic emulsion",
          "type": "DRUG"
        },
        {
          "name": "carboxymethylcellulose-based lubricant eye drops",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Allergan",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2014-04-03",
      "completion_date": "2014-09-23",
      "has_results": true,
      "last_update_posted_date": "2019-04-18",
      "last_synced_at": "2026-09-24T19:29:57.755Z",
      "location_count": 1,
      "location_summary": "Andover, Massachusetts",
      "locations": [
        {
          "city": "Andover",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02121847"
    },
    {
      "nct_id": "NCT02395952",
      "title": "Healing of Persistent Epithelial Defects",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cornea"
      ],
      "interventions": [
        {
          "name": "carboxymethylcellulose sodium",
          "type": "DRUG"
        },
        {
          "name": "Acuvue Oasys Bandage Contact Lens",
          "type": "DEVICE"
        },
        {
          "name": "Ambiodisk",
          "type": "DEVICE"
        },
        {
          "name": "Prokera",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Milton S. Hershey Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2015-03",
      "completion_date": "2018-02",
      "has_results": false,
      "last_update_posted_date": "2019-02-05",
      "last_synced_at": "2026-09-24T19:29:57.755Z",
      "location_count": 1,
      "location_summary": "Hershey, Pennsylvania",
      "locations": [
        {
          "city": "Hershey",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02395952"
    },
    {
      "nct_id": "NCT00514852",
      "title": "Safety and Efficacy of an Artificial Tear for the Treatment of Dry Eye",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dry Eye Syndrome"
      ],
      "interventions": [
        {
          "name": "Carboxymethylcellulose and Glycerin based artificial tear",
          "type": "DRUG"
        },
        {
          "name": "Carboxymethylcellulose",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Allergan",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 316,
      "start_date": "2007-10",
      "completion_date": "2008-01",
      "has_results": true,
      "last_update_posted_date": "2009-12-15",
      "last_synced_at": "2026-09-24T19:29:57.755Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00514852"
    },
    {
      "nct_id": "NCT02100787",
      "title": "Changes in Tear Osmolarity Over Time With Sustained Use of TheraTears",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dry Eye Syndrome"
      ],
      "interventions": [
        {
          "name": "TheraTears lubricating drops",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Jenkins Eye Care",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 18,
      "start_date": "2014-04-10",
      "completion_date": "2016-06-30",
      "has_results": false,
      "last_update_posted_date": "2017-03-03",
      "last_synced_at": "2026-09-24T19:29:57.755Z",
      "location_count": 1,
      "location_summary": "Honolulu, Hawaii",
      "locations": [
        {
          "city": "Honolulu",
          "state": "Hawaii"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02100787"
    },
    {
      "nct_id": "NCT01459588",
      "title": "Safety, Efficacy, and Acceptability Study of an Eye Drop Formulation in Subjects With Dry Eye Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Dry Eye Syndromes"
      ],
      "interventions": [
        {
          "name": "Carboxymethylcellulose Based Eye Drop Formulation A",
          "type": "DRUG"
        },
        {
          "name": "Carboxymethylcellulose Based Eye Drop Formulation B",
          "type": "DRUG"
        },
        {
          "name": "Carboxymethylcellulose Based Preservative-Free Lubricant Eye Drops",
          "type": "DRUG"
        },
        {
          "name": "Carboxymethylcellulose Based Lubricant Eye Drops",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Allergan",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 315,
      "start_date": "2011-10-01",
      "completion_date": "2012-02-15",
      "has_results": true,
      "last_update_posted_date": "2019-04-16",
      "last_synced_at": "2026-09-24T19:29:57.755Z",
      "location_count": 1,
      "location_summary": "Petaluma, California",
      "locations": [
        {
          "city": "Petaluma",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01459588"
    },
    {
      "nct_id": "NCT07676084",
      "title": "Randomized Single Center Study to Evaluate Tolerability, Symptoms, and Visual Functional Outcomes With the Use of OTC Lubricating Eye Drops in Subjects With Dry Eye Disease",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Dry Eye Disease (DED)"
      ],
      "interventions": [
        {
          "name": "Preservative Free Polyethylene glycol 400 0.25%",
          "type": "DRUG"
        },
        {
          "name": "Propylene Glycol (0.6%)",
          "type": "DRUG"
        },
        {
          "name": "Carboxymethylcellulose sodium 0.5%, Glycerin 1.0%, Polysorbate 80 0.5%",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Andover Research Eye Institute",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2026-06-03",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-06-30",
      "last_synced_at": "2026-09-24T19:29:57.755Z",
      "location_count": 1,
      "location_summary": "Andover, Massachusetts",
      "locations": [
        {
          "city": "Andover",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07676084"
    },
    {
      "nct_id": "NCT05292755",
      "title": "Effects of Carboxymethylcellulose Artificial Tears on the Eye Microbiome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Dry Eye Syndromes"
      ],
      "interventions": [
        {
          "name": "Carboxymethylcellulose (CMC) Artificial Tears",
          "type": "DRUG"
        },
        {
          "name": "Preservative-free, CMC-free Artificial Tears (control)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 80,
      "start_date": "2022-04-22",
      "completion_date": "2022-07-01",
      "has_results": true,
      "last_update_posted_date": "2023-04-20",
      "last_synced_at": "2026-09-24T19:29:57.755Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05292755"
    }
  ]
}