{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Remote+Ischemic+Pre-conditioning",
    "query": {
      "intervention": "Remote Ischemic Pre-conditioning"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 40,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Remote+Ischemic+Pre-conditioning&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-11T01:16:00.698Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06825143",
      "title": "Therapeutic Strategies to Reduce Endothelial Ischemia-reperfusion Injury",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Metabolic Syndrome",
        "Vascular Injury",
        "Ischemic Preconditioning",
        "Endothelial Function (reactive Hyperemia)",
        "Endothelial Dysfunction"
      ],
      "interventions": [
        {
          "name": "Ischemic preconditioning",
          "type": "PROCEDURE"
        },
        {
          "name": "Intravenous lactate infusion",
          "type": "DRUG"
        },
        {
          "name": "No ischemic preconditioning (control)",
          "type": "PROCEDURE"
        },
        {
          "name": "Normal Saline Infusion (Placebo)",
          "type": "DRUG"
        },
        {
          "name": "Ischemic preconditioning and intravenous lactate",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG",
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Gary Van Guilder",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 68,
      "start_date": "2026-10-01",
      "completion_date": "2030-06-30",
      "has_results": false,
      "last_update_posted_date": "2025-02-13",
      "last_synced_at": "2026-09-11T01:16:00.698Z",
      "location_count": 1,
      "location_summary": "Gunnison, Colorado",
      "locations": [
        {
          "city": "Gunnison",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06825143"
    },
    {
      "nct_id": "NCT03329612",
      "title": "Remote Ischemic Preconditioning in ACS Patients",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Coronary Syndrome",
        "Renal Insufficiency",
        "Ischemia, Myocardial"
      ],
      "interventions": [
        {
          "name": "Remote Ischemic Preconditioning",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Henry Ford Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2016-10-26",
      "completion_date": "2018-12-30",
      "has_results": false,
      "last_update_posted_date": "2022-12-14",
      "last_synced_at": "2026-09-11T01:16:00.698Z",
      "location_count": 1,
      "location_summary": "Detroit, Michigan",
      "locations": [
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03329612"
    },
    {
      "nct_id": "NCT05279664",
      "title": "RIC-NEC Randomized Controlled Trial",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Necrotizing Enterocolitis"
      ],
      "interventions": [
        {
          "name": "Remote ischemic conditioning (RIC) + Standard of Care for NEC",
          "type": "OTHER"
        },
        {
          "name": "Standard of Care for NEC",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "The Hospital for Sick Children",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Weeks",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "0 Weeks and older"
      },
      "enrollment_count": 78,
      "start_date": "2023-02-09",
      "completion_date": "2026-03-18",
      "has_results": false,
      "last_update_posted_date": "2026-02-03",
      "last_synced_at": "2026-09-11T01:16:00.698Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05279664"
    },
    {
      "nct_id": "NCT03853473",
      "title": "Prehabilitation of Frail Surgical Cancer Patients Using Remote Ischemic Preconditioning",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Colon Cancer",
        "Fragility",
        "Prehabilitation",
        "Surgery"
      ],
      "interventions": [
        {
          "name": "Remote Ischemic Preconditioning",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Medical College of Wisconsin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "55 Years to 85 Years"
      },
      "enrollment_count": 17,
      "start_date": "2019-02-22",
      "completion_date": "2023-03-01",
      "has_results": true,
      "last_update_posted_date": "2024-09-19",
      "last_synced_at": "2026-09-11T01:16:00.698Z",
      "location_count": 1,
      "location_summary": "Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03853473"
    },
    {
      "nct_id": "NCT03236441",
      "title": "Biochemical Effects of Remote Ischemic Pre-Conditioning on Contrast-induced Acute Kidney Injury",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Contrast-induced Acute Kidney Injury"
      ],
      "interventions": [
        {
          "name": "RIPC",
          "type": "DEVICE"
        },
        {
          "name": "Sham-RIPC",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Oladipupo Olafiranye, MD, MS",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 110,
      "start_date": "2018-03-06",
      "completion_date": "2024-02-28",
      "has_results": true,
      "last_update_posted_date": "2025-01-09",
      "last_synced_at": "2026-09-11T01:16:00.698Z",
      "location_count": 2,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03236441"
    },
    {
      "nct_id": "NCT00975702",
      "title": "Remote Ischemic Preconditioning In Abdominal Organ Transplantation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Kidney Disease",
        "Liver Disease",
        "Pancreas Disease"
      ],
      "interventions": [
        {
          "name": "RIPC by Inflation of Pneumatic Tourniquet",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Medicine and Dentistry of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "5 Years and older"
      },
      "enrollment_count": 85,
      "start_date": "2009-04",
      "completion_date": "2014-06",
      "has_results": false,
      "last_update_posted_date": "2015-01-14",
      "last_synced_at": "2026-09-11T01:16:00.698Z",
      "location_count": 1,
      "location_summary": "Newark, New Jersey",
      "locations": [
        {
          "city": "Newark",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00975702"
    },
    {
      "nct_id": "NCT02587039",
      "title": "An Intervention to Reduce Delirium After Cardiac Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Delirium",
        "Congenital Heart Disease",
        "Coronary Artery Disease",
        "Heart Valve Disease"
      ],
      "interventions": [
        {
          "name": "Remote ischemic pre-conditioning",
          "type": "PROCEDURE"
        },
        {
          "name": "Delirium Assessment",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "BEHAVIORAL"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 53,
      "start_date": "2014-06",
      "completion_date": "2015-12",
      "has_results": false,
      "last_update_posted_date": "2016-08-11",
      "last_synced_at": "2026-09-11T01:16:00.698Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02587039"
    },
    {
      "nct_id": "NCT02381522",
      "title": "Remote Ischemic Pre-conditioning in Subarachnoid Hemorrhage",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Brain Aneurysms"
      ],
      "interventions": [
        {
          "name": "Remote Ischemic Pre-conditioning",
          "type": "OTHER"
        },
        {
          "name": "Sham RIPC",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Loma Linda University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 26,
      "start_date": "2015-03-01",
      "completion_date": "2017-12-20",
      "has_results": false,
      "last_update_posted_date": "2021-10-29",
      "last_synced_at": "2026-09-11T01:16:00.698Z",
      "location_count": 1,
      "location_summary": "Loma Linda, California",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02381522"
    },
    {
      "nct_id": "NCT01071265",
      "title": "Remote Ischemic Preconditioning in Cardiac Surgery Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiac Surgery"
      ],
      "interventions": [
        {
          "name": "Remote Ischemic Preconditioning",
          "type": "PROCEDURE"
        },
        {
          "name": "Sham",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "McMaster University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 250,
      "start_date": "2011-03",
      "completion_date": "2013-01",
      "has_results": false,
      "last_update_posted_date": "2015-09-28",
      "last_synced_at": "2026-09-11T01:16:00.698Z",
      "location_count": 2,
      "location_summary": "Portland, Maine • Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Portland",
          "state": "Maine"
        },
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01071265"
    },
    {
      "nct_id": "NCT01078272",
      "title": "The Saint Francis Remote Ischemic Preconditioning Trial (SaFR)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Coronary Artery Disease"
      ],
      "interventions": [
        {
          "name": "Remote ischemic preconditioning",
          "type": "OTHER"
        },
        {
          "name": "Sham Remote Ischemic Preconditioning",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "St. Francis Hospital, New York",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "40 Years to 80 Years"
      },
      "enrollment_count": 4,
      "start_date": "2010-03",
      "completion_date": "2011-10",
      "has_results": false,
      "last_update_posted_date": "2020-03-19",
      "last_synced_at": "2026-09-11T01:16:00.698Z",
      "location_count": 1,
      "location_summary": "Roslyn, New York",
      "locations": [
        {
          "city": "Roslyn",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01078272"
    }
  ]
}