{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Remote+Ischemic+Pre-conditioning&page=2",
    "query": {
      "intervention": "Remote Ischemic Pre-conditioning",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Remote+Ischemic+Pre-conditioning&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-25T21:04:04.215Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06825143",
      "title": "Therapeutic Strategies to Reduce Endothelial Ischemia-reperfusion Injury",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Metabolic Syndrome",
        "Vascular Injury",
        "Ischemic Preconditioning",
        "Endothelial Function (reactive Hyperemia)",
        "Endothelial Dysfunction"
      ],
      "interventions": [
        {
          "name": "Ischemic preconditioning",
          "type": "PROCEDURE"
        },
        {
          "name": "Intravenous lactate infusion",
          "type": "DRUG"
        },
        {
          "name": "No ischemic preconditioning (control)",
          "type": "PROCEDURE"
        },
        {
          "name": "Normal Saline Infusion (Placebo)",
          "type": "DRUG"
        },
        {
          "name": "Ischemic preconditioning and intravenous lactate",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG",
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Gary Van Guilder",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 68,
      "start_date": "2026-10-01",
      "completion_date": "2030-06-30",
      "has_results": false,
      "last_update_posted_date": "2025-02-13",
      "last_synced_at": "2026-09-25T21:04:04.215Z",
      "location_count": 1,
      "location_summary": "Gunnison, Colorado",
      "locations": [
        {
          "city": "Gunnison",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06825143"
    },
    {
      "nct_id": "NCT03814850",
      "title": "Remote Ischemic PreConditioning (RIPC)",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Unruptured Cerebral Aneurysm"
      ],
      "interventions": [
        {
          "name": "Standard Manual Aneroid Sphygmomanometer",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Sebastian Koch",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2024-12-01",
      "completion_date": "2025-12-31",
      "has_results": false,
      "last_update_posted_date": "2023-12-08",
      "last_synced_at": "2026-09-25T21:04:04.215Z",
      "location_count": 2,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03814850"
    },
    {
      "nct_id": "NCT01383317",
      "title": "Remote Ischemic PreConditioning Effect on Postsurgical Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain"
      ],
      "interventions": [
        {
          "name": "Thigh Tourniquet (VBM Single Use Tourniquet Cuff Items 20-34-722SLZ-1)",
          "type": "DEVICE"
        },
        {
          "name": "Sham RIPC",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "30 Years to 80 Years"
      },
      "enrollment_count": 64,
      "start_date": "2011-06",
      "completion_date": "2017-04-30",
      "has_results": true,
      "last_update_posted_date": "2018-09-05",
      "last_synced_at": "2026-09-25T21:04:04.215Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01383317"
    },
    {
      "nct_id": "NCT06456268",
      "title": "VibraCool Device to Reduce Pain and Opioid Use After Anterior Cruciate Ligament Reconstruction (ACLR)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "ACL",
        "Opioid Use",
        "Cryotherapy Effect",
        "Vibration; Exposure",
        "Pain, Postoperative"
      ],
      "interventions": [
        {
          "name": "VibraCool mechanical stimulation and neuromodulatory therapeutic device",
          "type": "DEVICE"
        },
        {
          "name": "Cryocompression (Game Ready, Bregs) device",
          "type": "DEVICE"
        },
        {
          "name": "Standard ice packs",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 130,
      "start_date": "2026-06",
      "completion_date": "2026-11-30",
      "has_results": false,
      "last_update_posted_date": "2026-01-07",
      "last_synced_at": "2026-09-25T21:04:04.215Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06456268"
    },
    {
      "nct_id": "NCT01541436",
      "title": "Remote Ischemic Preconditioning Mechanism Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Pain"
      ],
      "interventions": [
        {
          "name": "Remote Ischemic Preconditioning, Capsaicin, UV-B",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 20,
      "start_date": "2012-03",
      "completion_date": "2017-04-30",
      "has_results": false,
      "last_update_posted_date": "2018-08-10",
      "last_synced_at": "2026-09-25T21:04:04.215Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01541436"
    },
    {
      "nct_id": "NCT05355883",
      "title": "Remote Ischemic Conditioning, Bimanual Skill Learning, and Corticospinal Excitability",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Unilateral Cerebral Palsy",
        "Hemiplegic Cerebral Palsy",
        "Remote Ischemic Conditioning"
      ],
      "interventions": [
        {
          "name": "Remote Ischemic Conditioning (RIC)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sham conditioning",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Hand Arm Bimanual Intensive Therapy (HABIT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Bimanual Cup Stacking Training",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Balance training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "East Carolina University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "16 Years",
        "sex": "ALL",
        "summary": "6 Years to 16 Years"
      },
      "enrollment_count": 51,
      "start_date": "2021-12-18",
      "completion_date": "2025-05-30",
      "has_results": false,
      "last_update_posted_date": "2025-07-16",
      "last_synced_at": "2026-09-25T21:04:04.215Z",
      "location_count": 1,
      "location_summary": "Greenville, North Carolina",
      "locations": [
        {
          "city": "Greenville",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05355883"
    },
    {
      "nct_id": "NCT01403337",
      "title": "Cardiac Remote Ischemic Preconditioning Before Elective Major Vascular Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Peripheral Arterial Disease"
      ],
      "interventions": [
        {
          "name": "Ischemic preconditioning",
          "type": "OTHER"
        },
        {
          "name": "Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Center for Veterans Research and Education",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 205,
      "start_date": "2011-07",
      "completion_date": "2015-09",
      "has_results": false,
      "last_update_posted_date": "2016-03-16",
      "last_synced_at": "2026-09-25T21:04:04.215Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01403337"
    },
    {
      "nct_id": "NCT05279664",
      "title": "RIC-NEC Randomized Controlled Trial",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Necrotizing Enterocolitis"
      ],
      "interventions": [
        {
          "name": "Remote ischemic conditioning (RIC) + Standard of Care for NEC",
          "type": "OTHER"
        },
        {
          "name": "Standard of Care for NEC",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "The Hospital for Sick Children",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Weeks",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "0 Weeks and older"
      },
      "enrollment_count": 78,
      "start_date": "2023-02-09",
      "completion_date": "2026-03-18",
      "has_results": false,
      "last_update_posted_date": "2026-02-03",
      "last_synced_at": "2026-09-25T21:04:04.215Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05279664"
    },
    {
      "nct_id": "NCT06390358",
      "title": "Effects of Remote Cardiac Ischemic Preconditioning",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiac Function and Preconditioning"
      ],
      "interventions": [
        {
          "name": "Tefillin",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Jack Rubinstein",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 24,
      "start_date": "2024-05-01",
      "completion_date": "2025-05-01",
      "has_results": false,
      "last_update_posted_date": "2024-05-06",
      "last_synced_at": "2026-09-25T21:04:04.215Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06390358"
    },
    {
      "nct_id": "NCT00821522",
      "title": "The Influence of Remote Ischemic Preconditioning on Acute Kidney Injury After Cardiac Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Acute Kidney Insufficiency",
        "Acute Renal Insufficiency",
        "Acute Kidney Injury",
        "Ischemic Preconditioning"
      ],
      "interventions": [
        {
          "name": "Remote Ischemic Preconditioning",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Robert Kramer, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 120,
      "start_date": "2008-11",
      "completion_date": "2010-05",
      "has_results": false,
      "last_update_posted_date": "2021-11-17",
      "last_synced_at": "2026-09-25T21:04:04.215Z",
      "location_count": 1,
      "location_summary": "Portland, Maine",
      "locations": [
        {
          "city": "Portland",
          "state": "Maine"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00821522"
    }
  ]
}