{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Research+bone+marrow+%28OPTIONAL%29",
    "query": {
      "intervention": "Research bone marrow (OPTIONAL)"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 3,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-25T02:31:29.278Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02907918",
      "title": "Neoadjuvant Study of Palbociclib in Combination With Letrozole and Trastuzumab in Stage II-III ER+ HER2+ Breast Cancer",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Breast Cancer",
        "Cancer of Breast",
        "Breast Carcinoma"
      ],
      "interventions": [
        {
          "name": "Palbociclib",
          "type": "DRUG"
        },
        {
          "name": "Letrozole",
          "type": "DRUG"
        },
        {
          "name": "Trastuzumab",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Goserelin",
          "type": "DRUG"
        },
        {
          "name": "Breast surgery",
          "type": "PROCEDURE"
        },
        {
          "name": "Research tumor biopsy",
          "type": "PROCEDURE"
        },
        {
          "name": "Research bone marrow (OPTIONAL)",
          "type": "PROCEDURE"
        },
        {
          "name": "Research blood sample",
          "type": "PROCEDURE"
        },
        {
          "name": "Research blood for germline DNA",
          "type": "GENETIC"
        },
        {
          "name": "Blood for detection of circulating tumor cells",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BIOLOGICAL",
        "PROCEDURE",
        "GENETIC"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 26,
      "start_date": "2017-06-30",
      "completion_date": "2020-09-23",
      "has_results": true,
      "last_update_posted_date": "2021-09-29",
      "last_synced_at": "2026-09-25T02:31:29.278Z",
      "location_count": 3,
      "location_summary": "Phoenix, Arizona • St Louis, Missouri • Buffalo, New York",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Buffalo",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02907918"
    },
    {
      "nct_id": "NCT02604563",
      "title": "Aging, Geriatric Syndromes and Clonal Hematopoiesis",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Geriatrics",
        "Aged",
        "Geriatric Syndromes",
        "Cardiovascular Diseases"
      ],
      "interventions": [
        {
          "name": "Cognitive Assessment",
          "type": "OTHER"
        },
        {
          "name": "Activities of Daily Living Questionnaire",
          "type": "OTHER"
        },
        {
          "name": "Instrumental Activities of Daily Living, subscale of the OARS",
          "type": "OTHER"
        },
        {
          "name": "Karnofsky Self-reported Performance Rating Scale",
          "type": "OTHER"
        },
        {
          "name": "Number of Falls",
          "type": "OTHER"
        },
        {
          "name": "Physical Health Section, subscale of the OARS",
          "type": "OTHER"
        },
        {
          "name": "MOS Social Activity Survey",
          "type": "OTHER"
        },
        {
          "name": "Unintentional Weight Loss",
          "type": "OTHER"
        },
        {
          "name": "Peripheral Blood Draw",
          "type": "GENETIC"
        },
        {
          "name": "Buccal Swab",
          "type": "GENETIC"
        },
        {
          "name": "Heart Health and Smoking History from BRFSS questionnaire",
          "type": "OTHER"
        },
        {
          "name": "Gait Speed",
          "type": "OTHER"
        },
        {
          "name": "Grip Strength",
          "type": "OTHER"
        },
        {
          "name": "Height and Weight measurements",
          "type": "OTHER"
        },
        {
          "name": "Blood pressure measurement",
          "type": "OTHER"
        },
        {
          "name": "Optional bone marrow biopsy",
          "type": "PROCEDURE"
        },
        {
          "name": "Blood draw for trauma measurements",
          "type": "PROCEDURE"
        },
        {
          "name": "Femur head donation",
          "type": "OTHER"
        },
        {
          "name": "Knee bone fragments",
          "type": "OTHER"
        },
        {
          "name": "Bone marrow aspirate",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "GENETIC",
        "PROCEDURE"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 2000,
      "start_date": "2016-03-10",
      "completion_date": "2030-04-30",
      "has_results": false,
      "last_update_posted_date": "2026-07-13",
      "last_synced_at": "2026-09-25T02:31:29.278Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02604563"
    },
    {
      "nct_id": "NCT04968834",
      "title": "Genomically Profiling, Collecting, Archiving and Distributing Hematologic Malignancy Specimens",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Leukemia",
        "Myelodysplastic Syndromes",
        "Myeloproliferative Syndrome"
      ],
      "interventions": [
        {
          "name": "Genomic profiling",
          "type": "GENETIC"
        }
      ],
      "intervention_types": [
        "GENETIC"
      ],
      "sponsor": "Dana-Farber Cancer Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "Up to 30 Years"
      },
      "enrollment_count": 300,
      "start_date": "2021-06-11",
      "completion_date": "2033-06",
      "has_results": false,
      "last_update_posted_date": "2026-07-16",
      "last_synced_at": "2026-09-25T02:31:29.278Z",
      "location_count": 8,
      "location_summary": "Hartford, Connecticut • Portland, Maine • Boston, Massachusetts + 4 more",
      "locations": [
        {
          "city": "Hartford",
          "state": "Connecticut"
        },
        {
          "city": "Portland",
          "state": "Maine"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Lebanon",
          "state": "New Hampshire"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04968834"
    }
  ]
}