{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Restylane+Treatment&page=2",
    "query": {
      "intervention": "Restylane Treatment",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Restylane+Treatment&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-26T21:04:34.329Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01998581",
      "title": "A Safety and Effectiveness Study of JUVÉDERM VOLBELLA® XC Injectable Gel for Lip and Perioral Enhancement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Subjects Desiring Lip Augmentation"
      ],
      "interventions": [
        {
          "name": "JUVEDERM VOLBELLA® XC",
          "type": "DEVICE"
        },
        {
          "name": "Restylane-L®",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Allergan",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 225,
      "start_date": "2013-11-01",
      "completion_date": "2015-05-29",
      "has_results": true,
      "last_update_posted_date": "2019-04-26",
      "last_synced_at": "2026-09-26T21:04:34.329Z",
      "location_count": 1,
      "location_summary": "New Orleans, Louisiana",
      "locations": [
        {
          "city": "New Orleans",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01998581"
    },
    {
      "nct_id": "NCT00444626",
      "title": "A Study to Compare the Safety and Effectiveness of a Non-FDA Approved Device Dermal Gel Extra (DGE) and an FDA Approved Device for the Correction of Nasolabial Folds (NLFs)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Facial Wrinkles at the Nasolabial Folds"
      ],
      "interventions": [
        {
          "name": "Dermal Gel Extra (DGE)",
          "type": "DEVICE"
        },
        {
          "name": "Restylane",
          "type": "DEVICE"
        },
        {
          "name": "EMLA Cream",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Genzyme, a Sanofi Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 140,
      "start_date": "2007-05",
      "completion_date": "2008-07",
      "has_results": true,
      "last_update_posted_date": "2015-04-22",
      "last_synced_at": "2026-09-26T21:04:34.329Z",
      "location_count": 6,
      "location_summary": "Birmingham, Alabama • La Jolla, California • Miami Beach, Florida + 3 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Miami Beach",
          "state": "Florida"
        },
        {
          "city": "Westwood",
          "state": "New Jersey"
        },
        {
          "city": "White Plains",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00444626"
    },
    {
      "nct_id": "NCT03461198",
      "title": "Micro-injections of Transparent Hyaluronic Acid Gel (Restylane® Silk) for Rejuvenation of the Aging Cheek",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Wrinkle"
      ],
      "interventions": [
        {
          "name": "Restylane® Silk",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Goldman, Butterwick, Fitzpatrick and Groff",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2019-02-26",
      "completion_date": "2020-08-01",
      "has_results": false,
      "last_update_posted_date": "2019-05-03",
      "last_synced_at": "2026-09-26T21:04:34.329Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03461198"
    },
    {
      "nct_id": "NCT03160716",
      "title": "Injection Technique Assessment of Restylane Lyft With Lidocaine for Cheek Augmentation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cheek Augmentation",
        "Midface Contour Deficiencies"
      ],
      "interventions": [
        {
          "name": "Restylane Lyft with Lidocaine",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Galderma R&D",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2017-05-16",
      "completion_date": "2017-10-31",
      "has_results": true,
      "last_update_posted_date": "2022-08-26",
      "last_synced_at": "2026-09-26T21:04:34.329Z",
      "location_count": 4,
      "location_summary": "Beverly Hills, California • Los Angeles, California • Palo Alto, California + 1 more",
      "locations": [
        {
          "city": "Beverly Hills",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03160716"
    },
    {
      "nct_id": "NCT02955381",
      "title": "Restylane Silk Acne Scar Efficacy Evaluation Study",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acne",
        "Acne Scars",
        "AdverseEvent"
      ],
      "interventions": [
        {
          "name": "Restylane Silk, 1.0 ml",
          "type": "DEVICE"
        },
        {
          "name": "Saline, 1.0 ml",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Schweiger Dermatology, PLLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "22 Years to 55 Years"
      },
      "enrollment_count": 26,
      "start_date": "2017-03-28",
      "completion_date": "2019-04-18",
      "has_results": false,
      "last_update_posted_date": "2019-05-10",
      "last_synced_at": "2026-09-26T21:04:34.329Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02955381"
    },
    {
      "nct_id": "NCT01034956",
      "title": "Outcomes and Patient Experience After Soft Tissue Dermal Filler Injections",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Rhytids",
        "Wrinkles"
      ],
      "interventions": [
        {
          "name": "hyaluronic acid or calcium hydroxylapatite filler",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The New York Eye & Ear Infirmary",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 20,
      "start_date": "2009-11",
      "completion_date": "2010-05",
      "has_results": false,
      "last_update_posted_date": "2012-05-01",
      "last_synced_at": "2026-09-26T21:04:34.329Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01034956"
    },
    {
      "nct_id": "NCT06351358",
      "title": "Evaluation of the Effects of a Biostimulator and Dermal Fillers for Cheek Augmentation and Contour Deficiencies",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Photoaging",
        "Weight Loss",
        "Skin Laxity",
        "Photodamaged Skin",
        "Volume Deficiency of the Midface"
      ],
      "interventions": [
        {
          "name": "Sculptra treatment",
          "type": "DEVICE"
        },
        {
          "name": "Restylane Treatment",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Galderma R&D",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "22 Years to 65 Years"
      },
      "enrollment_count": 41,
      "start_date": "2024-02-19",
      "completion_date": "2025-05-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-15",
      "last_synced_at": "2026-09-26T21:04:34.329Z",
      "location_count": 2,
      "location_summary": "Washington D.C., District of Columbia • New York, New York",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06351358"
    },
    {
      "nct_id": "NCT05691972",
      "title": "Effectiveness and Safety of Restylane Contour in the Treatment of Temple Hollowing",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Temporal Hollowing"
      ],
      "interventions": [
        {
          "name": "Restylane Contour",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Galderma R&D",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 225,
      "start_date": "2023-03-14",
      "completion_date": "2024-12-11",
      "has_results": true,
      "last_update_posted_date": "2026-05-22",
      "last_synced_at": "2026-09-26T21:04:34.329Z",
      "location_count": 15,
      "location_summary": "Phoenix, Arizona • Encino, California • Los Angeles, California + 12 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Encino",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Redondo Beach",
          "state": "California"
        },
        {
          "city": "Solana Beach",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05691972"
    },
    {
      "nct_id": "NCT04162496",
      "title": "Restylane Refyne for Correction of Horizontal Neck Rhytides",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aging",
        "Wrinkle",
        "Rhytides"
      ],
      "interventions": [
        {
          "name": "Restylane Refyne",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Siperstein Dermatology",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 26,
      "start_date": "2020-08-11",
      "completion_date": "2021-11-30",
      "has_results": true,
      "last_update_posted_date": "2026-07-16",
      "last_synced_at": "2026-09-26T21:04:34.329Z",
      "location_count": 1,
      "location_summary": "Boynton Beach, Florida",
      "locations": [
        {
          "city": "Boynton Beach",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04162496"
    },
    {
      "nct_id": "NCT00765583",
      "title": "A Study to Determine How Long Restylane® Will Last After Initial Treatment With 2 Different Re-treatment Schedules.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Rhytids"
      ],
      "interventions": [
        {
          "name": "Restylane",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Medicis Aesthetics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 75,
      "start_date": "2005-11",
      "completion_date": "2009-02",
      "has_results": false,
      "last_update_posted_date": "2011-09-22",
      "last_synced_at": "2026-09-26T21:04:34.329Z",
      "location_count": 3,
      "location_summary": "Coral Gables, Florida • Chicago, Illinois • White Plains, New York",
      "locations": [
        {
          "city": "Coral Gables",
          "state": "Florida"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "White Plains",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00765583"
    }
  ]
}