{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Reward",
    "query": {
      "intervention": "Reward"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 647,
    "total_pages": 65,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Reward&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-05T00:21:52.604Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05988138",
      "title": "Prevention of Anhedonia in Children",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anhedonia",
        "Depression"
      ],
      "interventions": [
        {
          "name": "Family Promoting Positive Emotions",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Psychoeducation",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Vanderbilt University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "8 Years to 12 Years"
      },
      "enrollment_count": 73,
      "start_date": "2023-11-10",
      "completion_date": "2026-01-17",
      "has_results": true,
      "last_update_posted_date": "2026-07-09",
      "last_synced_at": "2026-09-05T00:21:52.604Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05988138"
    },
    {
      "nct_id": "NCT06725160",
      "title": "Parent Encouragement And Coaching of Happiness in Youth",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depression",
        "Parent-Child Relations"
      ],
      "interventions": [
        {
          "name": "Parent Coaching",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Active Control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "4 Years to 99 Years"
      },
      "enrollment_count": 180,
      "start_date": "2025-10-28",
      "completion_date": "2029-02-01",
      "has_results": false,
      "last_update_posted_date": "2026-01-28",
      "last_synced_at": "2026-09-05T00:21:52.604Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06725160"
    },
    {
      "nct_id": "NCT00846040",
      "title": "Reduced Carbohydrate Versus Fat in Obese Subjects",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Reduced fat diet",
          "type": "OTHER"
        },
        {
          "name": "Reduced carbohydrate diet",
          "type": "OTHER"
        },
        {
          "name": "Drug: f-18 fallypride",
          "type": "DRUG"
        },
        {
          "name": "fMRI",
          "type": "DEVICE"
        },
        {
          "name": "PET",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 43,
      "start_date": "2009-02-13",
      "completion_date": "2014-10-20",
      "has_results": true,
      "last_update_posted_date": "2021-04-15",
      "last_synced_at": "2026-09-05T00:21:52.604Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00846040"
    },
    {
      "nct_id": "NCT02494050",
      "title": "Telemedicine for Women With Anhedonia in Bipolar and Unipolar Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depression",
        "Bipolar Disorder",
        "Anhedonia"
      ],
      "interventions": [
        {
          "name": "Behavioral Activation-Full",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Behavioral Activation-Short",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Bipolar Disorder Collaborative Care",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "21 Years to 65 Years · Female only"
      },
      "enrollment_count": 17,
      "start_date": "2015-06",
      "completion_date": "2016-08",
      "has_results": false,
      "last_update_posted_date": "2016-09-30",
      "last_synced_at": "2026-09-05T00:21:52.604Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02494050"
    },
    {
      "nct_id": "NCT07607938",
      "title": "Psilocybin as a Novel Therapy for Residual Anhedonia",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Anhedonia",
        "Emotional Blunting"
      ],
      "interventions": [
        {
          "name": "Psilocybin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 90,
      "start_date": "2026-09",
      "completion_date": "2030-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-08-20",
      "last_synced_at": "2026-09-05T00:21:52.604Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07607938"
    },
    {
      "nct_id": "NCT02086201",
      "title": "Comparing Engage to PST for Late Life Depression",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Major Depression"
      ],
      "interventions": [
        {
          "name": "Problem Solving Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Engage",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 262,
      "start_date": "2014-05",
      "completion_date": "2020-03-31",
      "has_results": false,
      "last_update_posted_date": "2021-06-29",
      "last_synced_at": "2026-09-05T00:21:52.604Z",
      "location_count": 2,
      "location_summary": "White Plains, New York • Seattle, Washington",
      "locations": [
        {
          "city": "White Plains",
          "state": "New York"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02086201"
    },
    {
      "nct_id": "NCT05875181",
      "title": "Examining the Impact of Transcranial Focused Ultrasound (tFUS) on Reward Neural Circuitry",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Impulsive Behavior"
      ],
      "interventions": [
        {
          "name": "tFUS",
          "type": "DEVICE"
        },
        {
          "name": "Sham tFUS",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Mary Phillips, MD MD (Cantab)",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 0,
      "start_date": "2023-06-19",
      "completion_date": "2024-12",
      "has_results": false,
      "last_update_posted_date": "2024-12-13",
      "last_synced_at": "2026-09-05T00:21:52.604Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05875181"
    },
    {
      "nct_id": "NCT06312657",
      "title": "Behavioral Effects of Drugs Inpatient 44 Neurobehavioral Mechanisms of Opioid Choice",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Opioid Use Disorder"
      ],
      "interventions": [
        {
          "name": "Drug Cue",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Money",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Withdrawal",
          "type": "DRUG"
        },
        {
          "name": "Remifentanil",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "Joshua A. Lile, Ph.D.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 2,
      "start_date": "2023-03-01",
      "completion_date": "2025-03-28",
      "has_results": true,
      "last_update_posted_date": "2026-03-30",
      "last_synced_at": "2026-09-05T00:21:52.604Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06312657"
    },
    {
      "nct_id": "NCT03959202",
      "title": "A Personalized Behavioral Intervention to Improve Physical Activity, Sleep and Cognition in Sedentary Older Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Sleep"
      ],
      "interventions": [
        {
          "name": "ELDERFITNESS",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "60 Years to 85 Years"
      },
      "enrollment_count": 129,
      "start_date": "2019-07-11",
      "completion_date": "2023-02-28",
      "has_results": false,
      "last_update_posted_date": "2023-03-08",
      "last_synced_at": "2026-09-05T00:21:52.604Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03959202"
    },
    {
      "nct_id": "NCT03799341",
      "title": "Neurocognitive Factors in Substance Use Treatment Response: The Ways of Rewarding Abstinence Project",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cocaine Use Disorder"
      ],
      "interventions": [
        {
          "name": "Prize-Based Contingency Management",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Treatment As Usual Outpatient Substance Use Treatment",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 63,
      "start_date": "2019-11-13",
      "completion_date": "2024-04-12",
      "has_results": true,
      "last_update_posted_date": "2025-09-30",
      "last_synced_at": "2026-09-05T00:21:52.604Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03799341"
    }
  ]
}