{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Riboflavin+Placebo",
    "query": {
      "intervention": "Riboflavin Placebo"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 47,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Riboflavin+Placebo&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-22T09:15:56.243Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00044083",
      "title": "Clinical Trial of Tolcapone for Cognition in Schizophrenia",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Schizophrenia"
      ],
      "interventions": [
        {
          "name": "Placebo",
          "type": "OTHER"
        },
        {
          "name": "Tolcapone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "National Institute of Mental Health (NIMH)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 210,
      "start_date": "2002-08",
      "completion_date": "2015-12",
      "has_results": true,
      "last_update_posted_date": "2018-09-27",
      "last_synced_at": "2026-09-22T09:15:56.243Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00044083"
    },
    {
      "nct_id": "NCT00679666",
      "title": "Corneal Crosslinking in Keratoconus and Corneal Ectasia",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Progressive Keratoconus",
        "Corneal Ectasia"
      ],
      "interventions": [
        {
          "name": "Riboflavin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2008-04",
      "completion_date": "2010-10",
      "has_results": false,
      "last_update_posted_date": "2017-04-20",
      "last_synced_at": "2026-09-22T09:15:56.243Z",
      "location_count": 2,
      "location_summary": "Columbus, Ohio • Dublin, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        },
        {
          "city": "Dublin",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00679666"
    },
    {
      "nct_id": "NCT05907850",
      "title": "Effects of Riboflavin in Mitigating Muscle Soreness in Ultra-marathon Athletes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Muscle Soreness"
      ],
      "interventions": [
        {
          "name": "Riboflavin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Steven Moore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 150,
      "start_date": "2023-06-23",
      "completion_date": "2024-05-30",
      "has_results": false,
      "last_update_posted_date": "2025-04-03",
      "last_synced_at": "2026-09-22T09:15:56.243Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05907850"
    },
    {
      "nct_id": "NCT05314738",
      "title": "Safety and Efficacy of Corneal Cross-linking in Subjects With Keratoconus",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Progressive Keratoconus"
      ],
      "interventions": [
        {
          "name": "NXL Energy 1",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "NXL Energy 2",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "NXL Energy 3",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Sham Treatment",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Glaukos Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 150,
      "start_date": "2022-03-08",
      "completion_date": "2026-02",
      "has_results": false,
      "last_update_posted_date": "2024-07-08",
      "last_synced_at": "2026-09-22T09:15:56.243Z",
      "location_count": 3,
      "location_summary": "Dothan, Alabama • Teaneck, New Jersey • Westerville, Ohio",
      "locations": [
        {
          "city": "Dothan",
          "state": "Alabama"
        },
        {
          "city": "Teaneck",
          "state": "New Jersey"
        },
        {
          "city": "Westerville",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05314738"
    },
    {
      "nct_id": "NCT01287221",
      "title": "Study of Rifampicin in Multiple System Atrophy",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Multiple System Atrophy"
      ],
      "interventions": [
        {
          "name": "Rifampicin",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Phillip Low",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "30 Years to 80 Years"
      },
      "enrollment_count": 100,
      "start_date": "2011-03",
      "completion_date": "2013-01",
      "has_results": true,
      "last_update_posted_date": "2014-03-28",
      "last_synced_at": "2026-09-22T09:15:56.243Z",
      "location_count": 10,
      "location_summary": "Los Angeles, California • San Diego, California • Jacksonville, Florida + 7 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01287221"
    },
    {
      "nct_id": "NCT02773212",
      "title": "Targeting Anhedonia in Cocaine Use Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cocaine-Related Disorders",
        "Anhedonia"
      ],
      "interventions": [
        {
          "name": "d-amphetamine",
          "type": "DRUG"
        },
        {
          "name": "Contingency management",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Placebo (for d-amphetamine)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Illinois at Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 57,
      "start_date": "2017-02-01",
      "completion_date": "2022-04-04",
      "has_results": true,
      "last_update_posted_date": "2024-08-09",
      "last_synced_at": "2026-09-22T09:15:56.243Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02773212"
    },
    {
      "nct_id": "NCT03432572",
      "title": "Investigating Oral Agents for Urine Staining to Facilitate Intraoperative Observation of Ureteral Jets",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Ureteral Injury"
      ],
      "interventions": [
        {
          "name": "Pyridium",
          "type": "DRUG"
        },
        {
          "name": "Riboflavin",
          "type": "DRUG"
        },
        {
          "name": "Thiamine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Texas Tech University Health Sciences Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "75 Years",
        "sex": "FEMALE",
        "summary": "21 Years to 75 Years · Female only"
      },
      "enrollment_count": 120,
      "start_date": "2018-06-27",
      "completion_date": "2020-06-30",
      "has_results": false,
      "last_update_posted_date": "2020-08-11",
      "last_synced_at": "2026-09-22T09:15:56.243Z",
      "location_count": 1,
      "location_summary": "Lubbock, Texas",
      "locations": [
        {
          "city": "Lubbock",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03432572"
    },
    {
      "nct_id": "NCT03552016",
      "title": "Evaluation of Progression of Myopia in Children Treated With Vitamin B2 and Outdoor Sunlight Exposure",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Axial Myopia",
        "Refractive Errors"
      ],
      "interventions": [
        {
          "name": "Oral Riboflavin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Missouri-Columbia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "6 Years to 12 Years"
      },
      "enrollment_count": 0,
      "start_date": "2018-10-10",
      "completion_date": "2021-12-13",
      "has_results": false,
      "last_update_posted_date": "2026-08-24",
      "last_synced_at": "2026-09-22T09:15:56.243Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03552016"
    },
    {
      "nct_id": "NCT02896712",
      "title": "Developing Adaptive Interventions for Cocaine Cessation and Relapse Prevention",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cocaine-Related Disorders"
      ],
      "interventions": [
        {
          "name": "Acceptance and Commitment Therapy (ACT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Drug Counseling (DC)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Contingency Management (CM)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Modafinil",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 118,
      "start_date": "2016-11-18",
      "completion_date": "2021-09-13",
      "has_results": true,
      "last_update_posted_date": "2023-02-08",
      "last_synced_at": "2026-09-22T09:15:56.243Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02896712"
    },
    {
      "nct_id": "NCT06100939",
      "title": "Epithelium-On Corneal Cross-linking in Subjects 8 to 45 Years of Age With Keratoconus",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Keratoconus"
      ],
      "interventions": [
        {
          "name": "Riboflavin and Sodium Iodide solution and Ultraviolet-A treatment",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Placebo and sham treatment",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Epion Therapeutics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "8 Years to 45 Years"
      },
      "enrollment_count": 396,
      "start_date": "2023-10-30",
      "completion_date": "2026-06-12",
      "has_results": false,
      "last_update_posted_date": "2026-06-25",
      "last_synced_at": "2026-09-22T09:15:56.243Z",
      "location_count": 13,
      "location_summary": "Rowland Heights, California • San Francisco, California • Miami, Florida + 10 more",
      "locations": [
        {
          "city": "Rowland Heights",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Hoffman Estates",
          "state": "Illinois"
        },
        {
          "city": "Brookline",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06100939"
    }
  ]
}