{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Roxadustat", "query": { "intervention": "Roxadustat" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 15, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Roxadustat&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-04T19:29:02.613Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00761657", "title": "Phase 2 Study of Roxadustat in Participants With Anemia and Chronic Kidney Disease Not Requiring Dialysis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Chronic Kidney Disease", "Anemia" ], "interventions": [ { "name": "Roxadustat", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Kyntra Bio", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 117, "start_date": "2006-11-01", "completion_date": "2010-06-21", "has_results": true, "last_update_posted_date": "2021-11-19", "last_synced_at": "2026-09-04T19:29:02.613Z", "location_count": 34, "location_summary": "Peoria, Arizona • Tempe, Arizona • Los Angeles, California + 31 more", "locations": [ { "city": "Peoria", "state": "Arizona" }, { "city": "Tempe", "state": "Arizona" }, { "city": "Los Angeles", "state": "California" }, { "city": "Mission Viejo", "state": "California" }, { "city": "Sacramento", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00761657" }, { "nct_id": "NCT01750190", "title": "A Study of Roxadustat for the Treatment of Anemia in Participants With Chronic Kidney Disease and Not Receiving Dialysis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "CKD Anemia" ], "interventions": [ { "name": "Roxadustat", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Kyntra Bio", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 922, "start_date": "2012-11-05", "completion_date": "2018-09-24", "has_results": true, "last_update_posted_date": "2021-10-01", "last_synced_at": "2026-09-04T19:29:02.613Z", "location_count": 55, "location_summary": "Huntsville, Alabama • Tempe, Arizona • Alhambra, California + 48 more", "locations": [ { "city": "Huntsville", "state": "Alabama" }, { "city": "Tempe", "state": "Arizona" }, { "city": "Alhambra", "state": "California" }, { "city": "Chula Vista", "state": "California" }, { "city": "Inglewood", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01750190" }, { "nct_id": "NCT04410198", "title": "Study of Roxadustat Conversion in Participants Receiving Stable Erythropoiesis-Stimulating Agent (ESA) or as Initial Anemia Treatment in Chronic Dialysis Participants", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Anemia Associated With End Stage Renal Disease (ESRD)" ], "interventions": [ { "name": "Roxadustat", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Kyntra Bio", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 203, "start_date": "2020-05-26", "completion_date": "2021-10-11", "has_results": true, "last_update_posted_date": "2022-09-13", "last_synced_at": "2026-09-04T19:29:02.613Z", "location_count": 9, "location_summary": "Englewood, Colorado • Caldwell, Idaho • Baton Rouge, Louisiana + 6 more", "locations": [ { "city": "Englewood", "state": "Colorado" }, { "city": "Caldwell", "state": "Idaho" }, { "city": "Baton Rouge", "state": "Louisiana" }, { "city": "Kalamazoo", "state": "Michigan" }, { "city": "Tupelo", "state": "Mississippi" } ], "official_url": "https://clinicaltrials.gov/study/NCT04410198" }, { "nct_id": "NCT02174731", "title": "Safety and Efficacy Study of Roxadustat to Treat Anemia in Patients With Chronic Kidney Disease, on Dialysis.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Anemia" ], "interventions": [ { "name": "Roxadustat", "type": "DRUG" }, { "name": "Epoetin alfa", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "AstraZeneca", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "130 Years", "sex": "ALL", "summary": "18 Years to 130 Years" }, "enrollment_count": 2133, "start_date": "2014-07-01", "completion_date": "2018-09-26", "has_results": true, "last_update_posted_date": "2019-12-16", "last_synced_at": "2026-09-04T19:29:02.613Z", "location_count": 51, "location_summary": "Huntsville, Alabama • El Centro, California • Fairfield, California + 41 more", "locations": [ { "city": "Huntsville", "state": "Alabama" }, { "city": "El Centro", "state": "California" }, { "city": "Fairfield", "state": "California" }, { "city": "Glendale", "state": "California" }, { "city": "Long Beach", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02174731" }, { "nct_id": "NCT02273726", "title": "Study to Evaluate the Efficacy and Safety of Roxadustat in the Treatment of Anemia in Participants With ESRD on Stable Dialysis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "CKD Anemia in Stable Dialysis Patients" ], "interventions": [ { "name": "Epoetin Alfa", "type": "DRUG" }, { "name": "Roxadustat", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Kyntra Bio", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 741, "start_date": "2015-01-15", "completion_date": "2018-09-19", "has_results": true, "last_update_posted_date": "2021-10-29", "last_synced_at": "2026-09-04T19:29:02.613Z", "location_count": 74, "location_summary": "Phoenix, Arizona • Pine Bluff, Arkansas • Chula Vista, California + 58 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Pine Bluff", "state": "Arkansas" }, { "city": "Chula Vista", "state": "California" }, { "city": "Chula Vista", "state": "California" }, { "city": "La Mesa", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02273726" }, { "nct_id": "NCT01414075", "title": "Study of Roxadustat (FG-4592) to Correct Anemia in Newly Initiated Dialysis Participants Not on Erythropoiesis-Stimulating Agent Treatment", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Dialysis", "Anemia" ], "interventions": [ { "name": "Roxadustat", "type": "DRUG" }, { "name": "Oral Iron", "type": "DRUG" }, { "name": "IV Iron", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Kyntra Bio", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 60, "start_date": "2011-07-21", "completion_date": "2013-01-10", "has_results": true, "last_update_posted_date": "2021-10-01", "last_synced_at": "2026-09-04T19:29:02.613Z", "location_count": 3, "location_summary": "Northridge, California • Yuba City, California • Detroit, Michigan", "locations": [ { "city": "Northridge", "state": "California" }, { "city": "Yuba City", "state": "California" }, { "city": "Detroit", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT01414075" }, { "nct_id": "NCT01244763", "title": "Study of Roxadustat in Non-Dialysis Chronic Kidney Disease Participants With Anemia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Chronic Kidney Disease", "Anemia" ], "interventions": [ { "name": "Roxadustat", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Kyntra Bio", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 145, "start_date": "2010-10-29", "completion_date": "2012-06-13", "has_results": true, "last_update_posted_date": "2022-02-10", "last_synced_at": "2026-09-04T19:29:02.613Z", "location_count": 35, "location_summary": "Mobile, Alabama • Pine Bluff, Arkansas • Azusa, California + 32 more", "locations": [ { "city": "Mobile", "state": "Alabama" }, { "city": "Pine Bluff", "state": "Arkansas" }, { "city": "Azusa", "state": "California" }, { "city": "Chula Vista", "state": "California" }, { "city": "Downey", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01244763" }, { "nct_id": "NCT01630889", "title": "Open-Label Extension Study for the Long-Term Efficacy and Safety of Roxadustat in Participants With Dialysis and Non-Dialysis Chronic Kidney Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Chronic Kidney Disease", "End Stage Renal Disease", "Anemia" ], "interventions": [ { "name": "Roxadustat", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Kyntra Bio", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 15, "start_date": "2012-05-18", "completion_date": "2019-12-12", "has_results": true, "last_update_posted_date": "2021-10-01", "last_synced_at": "2026-09-04T19:29:02.613Z", "location_count": 4, "location_summary": "Riverside, California • Greenbelt, Maryland • Asheville, North Carolina + 1 more", "locations": [ { "city": "Riverside", "state": "California" }, { "city": "Greenbelt", "state": "Maryland" }, { "city": "Asheville", "state": "North Carolina" }, { "city": "Arlington", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01630889" }, { "nct_id": "NCT02174627", "title": "Safety and Efficacy Study of Roxadustat to Treat Anemia in Patients With Chronic Kidney Disease (CKD), Not on Dialysis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Anemia" ], "interventions": [ { "name": "Roxadustat", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "AstraZeneca", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "130 Years", "sex": "ALL", "summary": "18 Years to 130 Years" }, "enrollment_count": 2781, "start_date": "2014-06-26", "completion_date": "2018-10-04", "has_results": true, "last_update_posted_date": "2019-12-16", "last_synced_at": "2026-09-04T19:29:02.613Z", "location_count": 97, "location_summary": "Birmingham, Alabama • Huntsville, Alabama • Phoenix, Arizona + 72 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Huntsville", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Bakersfield", "state": "California" }, { "city": "El Centro", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02174627" }, { "nct_id": "NCT03263091", "title": "Efficacy and Safety of Roxadustat for Treatment of Anemia in Participants With Lower Risk Myelodysplastic Syndrome With Low Red Blood Cell Transfusion Burden", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Primary MDS (Very Low, Low or Intermediate IPSS-R With <5% Blasts)", "Anemia" ], "interventions": [ { "name": "Roxadustat", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Kyntra Bio", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 184, "start_date": "2018-01-29", "completion_date": "2023-06-20", "has_results": true, "last_update_posted_date": "2024-08-01", "last_synced_at": "2026-09-04T19:29:02.613Z", "location_count": 30, "location_summary": "Bakersfield, California • Beverly Hills, California • Burbank, California + 25 more", "locations": [ { "city": "Bakersfield", "state": "California" }, { "city": "Beverly Hills", "state": "California" }, { "city": "Burbank", "state": "California" }, { "city": "Encino", "state": "California" }, { "city": "Laguna Hills", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03263091" } ] }