{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=SAMe&page=12",
    "query": {
      "intervention": "SAMe",
      "page": 12
    },
    "page_size": 10
  },
  "pagination": {
    "page": 12,
    "page_size": 10,
    "total_count": 8106,
    "total_pages": 811,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=SAMe&page=13&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=SAMe&page=11&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-21T14:32:36.241Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01156480",
      "title": "Anti-inflammatory Treatment at the Onset of Necrotizing Enterocolitis (NEC) in Preterm Infants",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Necrotizing Enterocolitis"
      ],
      "interventions": [
        {
          "name": "hydrocortisone",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Endeavor Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Days",
        "maximum_age": "6 Months",
        "sex": "ALL",
        "summary": "0 Days to 6 Months"
      },
      "enrollment_count": 2,
      "start_date": "2009-09",
      "completion_date": "2012-11",
      "has_results": true,
      "last_update_posted_date": "2020-09-09",
      "last_synced_at": "2026-10-21T14:32:36.241Z",
      "location_count": 2,
      "location_summary": "Chicago, Illinois • Evanston, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Evanston",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01156480"
    },
    {
      "nct_id": "NCT04879862",
      "title": "Locomotor and Bladder Function in Individuals With Acute Spinal Cord Injury",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spinal Cord Injuries"
      ],
      "interventions": [
        {
          "name": "Epidural stimulation + Stand Training",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Epidural stimulation + Step Training",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Epidural stimulation + Bladder Capacity Training",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Epidural stimulation + Bladder Voiding Efficiency Training",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Claudia Angeli",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 16,
      "start_date": "2022-04-04",
      "completion_date": "2029-04-28",
      "has_results": false,
      "last_update_posted_date": "2026-05-04",
      "last_synced_at": "2026-10-21T14:32:36.241Z",
      "location_count": 1,
      "location_summary": "West Orange, New Jersey",
      "locations": [
        {
          "city": "West Orange",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04879862"
    },
    {
      "nct_id": "NCT02068703",
      "title": "Sleep Enhancing Tools: Pilot Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sleep",
        "Pain"
      ],
      "interventions": [
        {
          "name": "Sleep Education Presentation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sleep Tool Demonstration",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 120,
      "start_date": "2014-02",
      "completion_date": "2015-09",
      "has_results": false,
      "last_update_posted_date": "2016-06-28",
      "last_synced_at": "2026-10-21T14:32:36.241Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02068703"
    },
    {
      "nct_id": "NCT02036970",
      "title": "Bardoxolone Methyl Evaluation in Patients With Pulmonary Hypertension (PH) - LARIAT",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Pulmonary Arterial Hypertension",
        "Pulmonary Hypertension",
        "Interstitial Lung Disease",
        "Idiopathic Interstitial Pneumonia",
        "Idiopathic Pulmonary Fibrosis",
        "Sarcoidosis",
        "Respiratory Bronchiolitis Associated Interstitial Lung Disease",
        "Desquamative Interstitial Pneumonia",
        "Cryptogenic Organizing Pneumonia",
        "Acute Interstitial Pneumonitis",
        "Idiopathic Lymphoid Interstitial Pneumonia",
        "Idiopathic Pleuroparenchymal Fibroelastosis"
      ],
      "interventions": [
        {
          "name": "Bardoxolone methyl",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Biogen",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 166,
      "start_date": "2014-05-31",
      "completion_date": "2018-05-16",
      "has_results": true,
      "last_update_posted_date": "2025-06-10",
      "last_synced_at": "2026-10-21T14:32:36.241Z",
      "location_count": 30,
      "location_summary": "Phoenix, Arizona • Beverly Hills, California • Los Angeles, California + 20 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Beverly Hills",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02036970"
    },
    {
      "nct_id": "NCT04558541",
      "title": "A Developmental Framework For Linking Phonological And Morpho-syntactic Sequential Pattern Rules In DLD: Production",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Developmental Language Disorder",
        "Speech Sound Disorder",
        "Specific Language Impairment"
      ],
      "interventions": [
        {
          "name": "Sensitivity to phonological rules",
          "type": "OTHER"
        },
        {
          "name": "Sensitivity to semantic category cues.",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Father Flanagan's Boys' Home",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": "8 Years",
        "sex": "ALL",
        "summary": "4 Years to 8 Years"
      },
      "enrollment_count": 400,
      "start_date": "2022-08-07",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-10-27",
      "last_synced_at": "2026-10-21T14:32:36.241Z",
      "location_count": 2,
      "location_summary": "Tucson, Arizona • Omaha, Nebraska",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04558541"
    },
    {
      "nct_id": "NCT04679441",
      "title": "A Novel Computer-Based Functional Skills Assessment and Training Program",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Mild Cognitive Impairment",
        "Healthy Aging"
      ],
      "interventions": [
        {
          "name": "The Computerized Functional Skills Assessment and Training Program",
          "type": "DEVICE"
        },
        {
          "name": "Brain HQ Double Decision",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "i-Function, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "60 Years to 100 Years"
      },
      "enrollment_count": 180,
      "start_date": "2021-08-01",
      "completion_date": "2023-05-31",
      "has_results": false,
      "last_update_posted_date": "2023-05-08",
      "last_synced_at": "2026-10-21T14:32:36.241Z",
      "location_count": 2,
      "location_summary": "Miami, Florida • New York, New York",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04679441"
    },
    {
      "nct_id": "NCT00867854",
      "title": "Treatment De-Intensification and Residual HIV-1 in Youth",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "HIV-1",
        "HIV Infections"
      ],
      "interventions": [
        {
          "name": "Blood draw",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "24 Years",
        "sex": "ALL",
        "summary": "18 Years to 24 Years"
      },
      "enrollment_count": 34,
      "start_date": "2009-02",
      "completion_date": "2011-10",
      "has_results": false,
      "last_update_posted_date": "2017-02-28",
      "last_synced_at": "2026-10-21T14:32:36.241Z",
      "location_count": 16,
      "location_summary": "Los Angeles, California • San Francisco, California • Washington D.C., District of Columbia + 10 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Fort Lauderdale",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00867854"
    },
    {
      "nct_id": "NCT01727505",
      "title": "Volume Guarantee Ventilation in Preterm Infants With Frequent Episodes of Hypoxemia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Episodic Hypoxemia in Mechanically Ventilated Preterm Infants"
      ],
      "interventions": [
        {
          "name": "Sequence A: Conventional-Volume Guarantee",
          "type": "DEVICE"
        },
        {
          "name": "Sequence B: Volume Guarantee-Conventional",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 30,
      "start_date": "2012-11",
      "completion_date": "2015-11",
      "has_results": true,
      "last_update_posted_date": "2017-03-01",
      "last_synced_at": "2026-10-21T14:32:36.241Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01727505"
    },
    {
      "nct_id": "NCT06996366",
      "title": "Reducing Racial and Ethnic Disparities in Medicare Annual Wellness Visit Uptake",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Annual Wellness Visit"
      ],
      "interventions": [
        {
          "name": "Outreach to encourage Annual Wellness Visit completion",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "66 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "66 Years and older"
      },
      "enrollment_count": 174,
      "start_date": "2025-04-22",
      "completion_date": "2025-10-21",
      "has_results": false,
      "last_update_posted_date": "2026-03-23",
      "last_synced_at": "2026-10-21T14:32:36.241Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06996366"
    },
    {
      "nct_id": "NCT05405985",
      "title": "Study to Access the Relative Bioavailability of Subcutaneous Dose of Nemolizumab When Administered Via Auto-Injector Versus Dual-Chamber Syringe",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Healthy Volunteers"
      ],
      "interventions": [
        {
          "name": "Nemolizumab",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Galderma R&D",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 192,
      "start_date": "2022-08-11",
      "completion_date": "2022-12-08",
      "has_results": true,
      "last_update_posted_date": "2025-01-03",
      "last_synced_at": "2026-10-21T14:32:36.241Z",
      "location_count": 2,
      "location_summary": "Tempe, Arizona • Lincoln, Nebraska",
      "locations": [
        {
          "city": "Tempe",
          "state": "Arizona"
        },
        {
          "city": "Lincoln",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05405985"
    }
  ]
}