{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=SAVR+Implantation",
    "query": {
      "intervention": "SAVR Implantation"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 9,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-07T07:34:47.402Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01586910",
      "title": "Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Severe, Symptomatic Aortic Stenosis in Intermediate Risk Subjects Who Need Aortic Valve Replacement (SURTAVI).",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Severe Aortic Stenosis"
      ],
      "interventions": [
        {
          "name": "Medtronic CoreValve® System Transcatheter Aortic Valve Implantation (TAVI)",
          "type": "DEVICE"
        },
        {
          "name": "Surgical Aortic Valve Replacement (SAVR)",
          "type": "PROCEDURE"
        },
        {
          "name": "Medtronic CoreValve® Evolut R System Transcatheter Aortic Valve Implantation (TAVI)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Medtronic Cardiovascular",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 1746,
      "start_date": "2012-04",
      "completion_date": "2026-11",
      "has_results": true,
      "last_update_posted_date": "2026-06-24",
      "last_synced_at": "2026-09-07T07:34:47.402Z",
      "location_count": 65,
      "location_summary": "Phoenix, Arizona • Hollywood, California • La Jolla, California + 55 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Hollywood",
          "state": "California"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Mountain View",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01586910"
    },
    {
      "nct_id": "NCT07413965",
      "title": "TAVR vs SAVR in Severe Bicuspid Aortic Stenosis",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bicuspid Aortic Valve Disease"
      ],
      "interventions": [
        {
          "name": "Transcatheter Aortic Valve Replacement",
          "type": "PROCEDURE"
        },
        {
          "name": "the open chest surgery to replace the aortic valve",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Cedars-Sinai Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 1200,
      "start_date": "2026-07-23",
      "completion_date": "2040-05-10",
      "has_results": false,
      "last_update_posted_date": "2026-08-14",
      "last_synced_at": "2026-09-07T07:34:47.402Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07413965"
    },
    {
      "nct_id": "NCT01240902",
      "title": "Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Symptomatic Severe Aortic Stenosis in High Risk and Very High Risk Subjects Who Need Aortic Valve Replacement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Severe Aortic Stenosis"
      ],
      "interventions": [
        {
          "name": "Medtronic CoreValve® System Transcatheter Aortic Valve Implantation (TAVI)",
          "type": "DEVICE"
        },
        {
          "name": "Surgical Aortic Valve Replacement (SAVR)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medtronic Cardiovascular",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 1453,
      "start_date": "2010-12-10",
      "completion_date": "2019-05-15",
      "has_results": true,
      "last_update_posted_date": "2022-10-25",
      "last_synced_at": "2026-09-07T07:34:47.402Z",
      "location_count": 45,
      "location_summary": "Phoenix, Arizona • Los Angeles, California • Mountain View, California + 35 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Mountain View",
          "state": "California"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01240902"
    },
    {
      "nct_id": "NCT01314313",
      "title": "PARTNER II Trial: Placement of AoRTic TraNscathetER Valves II - XT Intermediate and High Risk",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Symptomatic Severe Aortic Stenosis"
      ],
      "interventions": [
        {
          "name": "TAVR Implantation with SAPIEN XT",
          "type": "DEVICE"
        },
        {
          "name": "SAVR Implantation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Edwards Lifesciences",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 2032,
      "start_date": "2011-03",
      "completion_date": "2024-01-17",
      "has_results": true,
      "last_update_posted_date": "2024-03-07",
      "last_synced_at": "2026-09-07T07:34:47.402Z",
      "location_count": 55,
      "location_summary": "Little Rock, Arkansas • La Jolla, California • Los Angeles, California + 46 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01314313"
    },
    {
      "nct_id": "NCT02701283",
      "title": "Medtronic Evolut Transcatheter Aortic Valve Replacement in Low Risk Patients",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aortic Valve Stenosis"
      ],
      "interventions": [
        {
          "name": "Medtronic Transcatheter Aortic Valve Replacement Systems",
          "type": "DEVICE"
        },
        {
          "name": "Surgical Aortic Valve Replacement (SAVR)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medtronic Cardiovascular",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 2223,
      "start_date": "2016-03",
      "completion_date": "2029-06",
      "has_results": true,
      "last_update_posted_date": "2026-05-07",
      "last_synced_at": "2026-09-07T07:34:47.402Z",
      "location_count": 61,
      "location_summary": "Phoenix, Arizona • La Jolla, California • Los Angeles, California + 53 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Mountain View",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02701283"
    },
    {
      "nct_id": "NCT02628899",
      "title": "Feasibility of Transcatheter Aortic Valve Replacement in Low-Risk Patients With Symptomatic, Severe Aortic Stenosis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aortic Stenosis"
      ],
      "interventions": [
        {
          "name": "Transfemoral TAVR",
          "type": "DEVICE"
        },
        {
          "name": "SAVR",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medstar Health Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 277,
      "start_date": "2016-01",
      "completion_date": "2023-01",
      "has_results": false,
      "last_update_posted_date": "2024-05-16",
      "last_synced_at": "2026-09-07T07:34:47.402Z",
      "location_count": 11,
      "location_summary": "Sacramento, California • San Diego, California • Washington D.C., District of Columbia + 7 more",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Marietta",
          "state": "Georgia"
        },
        {
          "city": "Portland",
          "state": "Maine"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02628899"
    },
    {
      "nct_id": "NCT03003299",
      "title": "PARTNER 3 Trial - Aortic Valve-in-Valve",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aortic Stenosis",
        "Aortic Stenosis, Severe"
      ],
      "interventions": [
        {
          "name": "Edwards SAPIEN 3/SAPIEN 3 Ultra THV",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Edwards Lifesciences",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 125,
      "start_date": "2017-01-05",
      "completion_date": "2038-04",
      "has_results": false,
      "last_update_posted_date": "2024-05-10",
      "last_synced_at": "2026-09-07T07:34:47.402Z",
      "location_count": 50,
      "location_summary": "Phoenix, Arizona • Los Angeles, California • Sacramento, California + 43 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03003299"
    },
    {
      "nct_id": "NCT06817148",
      "title": "Bicuspid Aortic Valve Replacement: Evaluation of Transcatheter Versus Surgery-Pilot Trial",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aortic Valve Stenosis",
        "Bicuspid Aortic Valve"
      ],
      "interventions": [
        {
          "name": "transcatheter aortic valve replacement (TAVR)",
          "type": "PROCEDURE"
        },
        {
          "name": "surgical aortic valve replacement (SAVR)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Cedars-Sinai Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 250,
      "start_date": "2025-01-31",
      "completion_date": "2037-02-01",
      "has_results": false,
      "last_update_posted_date": "2025-02-10",
      "last_synced_at": "2026-09-07T07:34:47.402Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06817148"
    },
    {
      "nct_id": "NCT06608823",
      "title": "ARTIST: Aortic Regurgitation Trial Investigating Surgery Versus Trilogy™",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aortic Regurgitation",
        "Aortic Valve Insufficiency",
        "Aortic Insufficiency"
      ],
      "interventions": [
        {
          "name": "Transcatheter Aortic Valve Replacement (TAVR) using Trilogy THV System",
          "type": "DEVICE"
        },
        {
          "name": "SAVR",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "JenaValve Technology, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 1016,
      "start_date": "2025-06-18",
      "completion_date": "2036-02",
      "has_results": false,
      "last_update_posted_date": "2026-07-07",
      "last_synced_at": "2026-09-07T07:34:47.402Z",
      "location_count": 29,
      "location_summary": "Burlingame, California • La Jolla, California • Los Angeles, California + 25 more",
      "locations": [
        {
          "city": "Burlingame",
          "state": "California"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Thousand Oaks",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06608823"
    }
  ]
}