{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=SHAM&page=31",
    "query": {
      "intervention": "SHAM",
      "page": 31
    },
    "page_size": 10
  },
  "pagination": {
    "page": 31,
    "page_size": 10,
    "total_count": 3882,
    "total_pages": 389,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=SHAM&page=32&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=SHAM&page=30&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-23T18:45:47.071Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05731986",
      "title": "Spinal Cord Transcutaneous Stimulation Effect on Blood Pressure in Acute Spinal Cord Injury (SCI)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spinal Cord Injuries",
        "Spinal Cord Diseases",
        "Trauma, Nervous System",
        "Nervous System Diseases",
        "Central Nervous System Diseases",
        "Hypotension",
        "Orthostatic Hypotension",
        "Cardiovascular Diseases",
        "Acute Spinal Cord Injury",
        "Blood Pressure"
      ],
      "interventions": [
        {
          "name": "Orthostatic challenge",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Biostim-5 transcutaneous spinal stimulation - Mapping",
          "type": "DEVICE"
        },
        {
          "name": "Biostim-5 transcutaneous spinal stimulation - \"Optimal\" testing",
          "type": "DEVICE"
        },
        {
          "name": "Biostim-5 transcutaneous spinal stimulation - \"Sham\" testing",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "DEVICE"
      ],
      "sponsor": "Kessler Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 12,
      "start_date": "2023-12-01",
      "completion_date": "2026-08",
      "has_results": false,
      "last_update_posted_date": "2025-09-02",
      "last_synced_at": "2026-10-23T18:45:47.071Z",
      "location_count": 1,
      "location_summary": "West Orange, New Jersey",
      "locations": [
        {
          "city": "West Orange",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05731986"
    },
    {
      "nct_id": "NCT03556124",
      "title": "Transcranial Direct Current Stimulation in Major Depression",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Major Depressive Disorder"
      ],
      "interventions": [
        {
          "name": "Active - HD tDCS",
          "type": "DEVICE"
        },
        {
          "name": "Sham - HD tDCS",
          "type": "DEVICE"
        },
        {
          "name": "Active - Conventional tDCS",
          "type": "DEVICE"
        },
        {
          "name": "Sham - Conventional tDCS",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 66,
      "start_date": "2018-02-02",
      "completion_date": "2020-05-31",
      "has_results": false,
      "last_update_posted_date": "2020-07-31",
      "last_synced_at": "2026-10-23T18:45:47.071Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03556124"
    },
    {
      "nct_id": "NCT03916341",
      "title": "Smoking and Ventricular Repolarization",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sudden Cardiac Death",
        "Prolonged QTc Interval"
      ],
      "interventions": [
        {
          "name": "EC with nicotine",
          "type": "OTHER"
        },
        {
          "name": "EC without nicotine",
          "type": "OTHER"
        },
        {
          "name": "control",
          "type": "OTHER"
        },
        {
          "name": "TC with nicotine (own brand)",
          "type": "OTHER"
        },
        {
          "name": "research TC with very low level nicotine",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "21 Years to 45 Years"
      },
      "enrollment_count": 110,
      "start_date": "2019-10-01",
      "completion_date": "2023-04-10",
      "has_results": false,
      "last_update_posted_date": "2023-10-04",
      "last_synced_at": "2026-10-23T18:45:47.071Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03916341"
    },
    {
      "nct_id": "NCT06480786",
      "title": "SCS for Patient With Painful Diabetic Neuropathy and Peripheral Arterial Disease",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Peripheral Arterial Disease",
        "Painful Diabetic Neuropathy",
        "Diabetes Mellitus, Type 2",
        "Chronic Pain",
        "Spinal Cord Stimulation",
        "Chronic Pain Syndrome",
        "Limb Pain"
      ],
      "interventions": [
        {
          "name": "Spinal cord stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Sham stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Nebraska",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "19 Years to 89 Years"
      },
      "enrollment_count": 15,
      "start_date": "2024-12-18",
      "completion_date": "2027-07",
      "has_results": false,
      "last_update_posted_date": "2025-10-22",
      "last_synced_at": "2026-10-23T18:45:47.071Z",
      "location_count": 1,
      "location_summary": "Omaha, Nebraska",
      "locations": [
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06480786"
    },
    {
      "nct_id": "NCT01444183",
      "title": "Stress Management Intervention for Living With Epilepsy (SMILE)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Epilepsy"
      ],
      "interventions": [
        {
          "name": "Progressive muscle relaxation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sham exercise",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Montefiore Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 95,
      "start_date": "2012-01",
      "completion_date": "2015-01",
      "has_results": false,
      "last_update_posted_date": "2018-04-19",
      "last_synced_at": "2026-10-23T18:45:47.071Z",
      "location_count": 3,
      "location_summary": "San Francisco, California • The Bronx, New York • Cincinnati, Ohio",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "The Bronx",
          "state": "New York"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01444183"
    },
    {
      "nct_id": "NCT03517761",
      "title": "Use of Bone Marrow Concentrate for Treatment of Alar, Accessory, and Transverse Ligament Injuries",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Craniocervical Injuries"
      ],
      "interventions": [
        {
          "name": "Bone Marrow Concentrate treatment",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Sham Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "Regenexx, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 80,
      "start_date": "2018-03-23",
      "completion_date": "2030-12",
      "has_results": false,
      "last_update_posted_date": "2025-04-06",
      "last_synced_at": "2026-10-23T18:45:47.071Z",
      "location_count": 1,
      "location_summary": "Broomfield, Colorado",
      "locations": [
        {
          "city": "Broomfield",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03517761"
    },
    {
      "nct_id": "NCT05309473",
      "title": "Acoustic Stimulation During Restricted Sleep After Sleep Deprivation",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sleep Deprivation",
        "Sleep Restriction",
        "Acoustic Stimulation",
        "Performance",
        "Alertness"
      ],
      "interventions": [
        {
          "name": "Philips SmartSleep Acoustic Stimulation Device",
          "type": "DEVICE"
        },
        {
          "name": "Sham (no Acoustic Stimulation)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Walter Reed Army Institute of Research (WRAIR)",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "39 Years",
        "sex": "ALL",
        "summary": "18 Years to 39 Years"
      },
      "enrollment_count": 44,
      "start_date": "2022-03-14",
      "completion_date": "2026-10",
      "has_results": false,
      "last_update_posted_date": "2024-04-23",
      "last_synced_at": "2026-10-23T18:45:47.071Z",
      "location_count": 1,
      "location_summary": "Silver Spring, Maryland",
      "locations": [
        {
          "city": "Silver Spring",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05309473"
    },
    {
      "nct_id": "NCT00971074",
      "title": "Study of Viscosupplementation for the Treatment of Knee Pain After Menisectomy",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Arthralgia"
      ],
      "interventions": [
        {
          "name": "Hylan G-F 20",
          "type": "DRUG"
        },
        {
          "name": "Sham Injection",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Grant Jones",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 0,
      "start_date": "2009-12",
      "completion_date": "2011-12",
      "has_results": false,
      "last_update_posted_date": "2021-02-25",
      "last_synced_at": "2026-10-23T18:45:47.071Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00971074"
    },
    {
      "nct_id": "NCT01213082",
      "title": "ProspectiveTrial of Proton Beam Combined With Anti-VEGF Therapy for Exudative Age-related Macular Degeneration (AMD)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Exudative Age-related Macular Degeneration"
      ],
      "interventions": [
        {
          "name": "24GyE proton and Anti-VEGF",
          "type": "DRUG"
        },
        {
          "name": "16GyE and anti-VEGF",
          "type": "DRUG"
        },
        {
          "name": "Sham Irradiation and anti-VEGF",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 34,
      "start_date": "2010-09",
      "completion_date": "2017-01-31",
      "has_results": true,
      "last_update_posted_date": "2018-07-17",
      "last_synced_at": "2026-10-23T18:45:47.071Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01213082"
    },
    {
      "nct_id": "NCT07254806",
      "title": "A Study to Evaluate the Effectiveness of IDCT (Intradiscal Cell Therapy) in Subjects With One Level, Symptomatic Mild to Moderate Lumbar Degenerative Disc Disease",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Degenerative Disc Disease"
      ],
      "interventions": [
        {
          "name": "IDCT (rebonuputemcel)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Sham (No Treatment)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "DiscGenics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 162,
      "start_date": "2025-12-23",
      "completion_date": "2028-11-24",
      "has_results": false,
      "last_update_posted_date": "2026-10-15",
      "last_synced_at": "2026-10-23T18:45:47.071Z",
      "location_count": 31,
      "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 28 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07254806"
    }
  ]
}