{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=SHAM-Intermittent+Room+Air&page=2", "query": { "intervention": "SHAM-Intermittent Room Air", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=SHAM-Intermittent+Room+Air&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-09-25T01:16:23.597Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02323698", "title": "Effects of Caffeine and Intermittent Hypoxia on Leg Function in Human Spinal Cord Injury", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Spinal Cord Injuries" ], "interventions": [ { "name": "Caffeine", "type": "DRUG" }, { "name": "AIH", "type": "OTHER" }, { "name": "Placebo", "type": "OTHER" }, { "name": "SHAM", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Spaulding Rehabilitation Hospital", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 36, "start_date": "2019-01-01", "completion_date": "2022-02-19", "has_results": true, "last_update_posted_date": "2023-12-13", "last_synced_at": "2026-09-25T01:16:23.597Z", "location_count": 1, "location_summary": "Cambridge, Massachusetts", "locations": [ { "city": "Cambridge", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT02323698" }, { "nct_id": "NCT03029559", "title": "Intermittent Hypoxia and Inspiratory Threshold Loading to Enhance Inspiratory Muscle Function", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Intermittent Hypoxia" ], "interventions": [ { "name": "Intermittent Hypoxia", "type": "OTHER" }, { "name": "Inspiratory Threshold Loading", "type": "OTHER" }, { "name": "Sham Intermittent Hypoxia", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "University of Florida", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "40 Years", "sex": "ALL", "summary": "18 Years to 40 Years" }, "enrollment_count": 20, "start_date": "2017-02-17", "completion_date": "2018-02-19", "has_results": false, "last_update_posted_date": "2019-06-20", "last_synced_at": "2026-09-25T01:16:23.597Z", "location_count": 1, "location_summary": "Gainesville, Florida", "locations": [ { "city": "Gainesville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT03029559" }, { "nct_id": "NCT04854057", "title": "Pairing Intermittent Hypoxia and Transcutaneous Electrical Spinal Cord Stimulation to Promote Arm Use After Cervical SCI", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Spinal Cord Injuries" ], "interventions": [ { "name": "AIH - Intermittent Hypoxia - hypoxia air mixture", "type": "OTHER" }, { "name": "SHAM - Intermittent Room Air - room air mixture", "type": "OTHER" }, { "name": "TESS - Transcutaneous Electrical Spinal Cord Stimulation + Functional Task Practice", "type": "DEVICE" } ], "intervention_types": [ "OTHER", "DEVICE" ], "sponsor": "Spaulding Rehabilitation Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 3, "start_date": "2021-03-03", "completion_date": "2021-10-22", "has_results": true, "last_update_posted_date": "2024-01-10", "last_synced_at": "2026-09-25T01:16:23.597Z", "location_count": 1, "location_summary": "Cambridge, Massachusetts", "locations": [ { "city": "Cambridge", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT04854057" }, { "nct_id": "NCT05377424", "title": "Adenosine 2A Receptor Antagonism and AIH in ALS", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "ALS" ], "interventions": [ { "name": "Consume 20mg of istradefylline", "type": "DRUG" }, { "name": "Low Oxygen therapy", "type": "OTHER" }, { "name": "Placebo counterpart to the istradefylline drug", "type": "DRUG" }, { "name": "SHAM counterpart to low oxygen therapy.", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "University of Florida", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "21 Years to 80 Years" }, "enrollment_count": 40, "start_date": "2022-06-21", "completion_date": "2026-08-31", "has_results": false, "last_update_posted_date": "2026-03-27", "last_synced_at": "2026-09-25T01:16:23.597Z", "location_count": 2, "location_summary": "Gainesville, Florida • Jacksonville, Florida", "locations": [ { "city": "Gainesville", "state": "Florida" }, { "city": "Jacksonville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT05377424" }, { "nct_id": "NCT05217498", "title": "Combining Low Oxygen Therapy and an Adenosine A2a Receptor Antagonist to Improve Functional Mobility After Spinal Cord Injury", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Spinal Cord Injuries", "Myelopathy" ], "interventions": [ { "name": "Istradefylline", "type": "DRUG" }, { "name": "low oxygen therapy", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "Randy Trumbower, PT, PhD", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 40, "start_date": "2027-09-01", "completion_date": "2028-06-30", "has_results": false, "last_update_posted_date": "2026-03-20", "last_synced_at": "2026-09-25T01:16:23.597Z", "location_count": 1, "location_summary": "Cambridge, Massachusetts", "locations": [ { "city": "Cambridge", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT05217498" }, { "nct_id": "NCT03644277", "title": "A Multi-Center Clinical Trial in Individuals With Spinal Cord Injury", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Spinal Cord Injuries" ], "interventions": [ { "name": "Acute Intermitted Hypoxia", "type": "OTHER" }, { "name": "Massed Practise", "type": "PROCEDURE" }, { "name": "Rapael Glove", "type": "OTHER" } ], "intervention_types": [ "OTHER", "PROCEDURE" ], "sponsor": "Shirley Ryan AbilityLab", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 121, "start_date": "2018-07-01", "completion_date": "2026-07-01", "has_results": false, "last_update_posted_date": "2025-07-24", "last_synced_at": "2026-09-25T01:16:23.597Z", "location_count": 3, "location_summary": "Chicago, Illinois • East Hanover, New Jersey", "locations": [ { "city": "Chicago", "state": "Illinois" }, { "city": "Chicago", "state": "Illinois" }, { "city": "East Hanover", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT03644277" }, { "nct_id": "NCT05495087", "title": "IHT for Mild Cognitive Impairment", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Mild Cognitive Impairment", "Memory Impairment" ], "interventions": [ { "name": "IHT Treatment", "type": "DEVICE" }, { "name": "Sham-IHT Control", "type": "OTHER" } ], "intervention_types": [ "DEVICE", "OTHER" ], "sponsor": "University of North Texas Health Science Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "55 Years", "maximum_age": "79 Years", "sex": "ALL", "summary": "55 Years to 79 Years" }, "enrollment_count": 66, "start_date": "2023-02-27", "completion_date": "2026-04-30", "has_results": false, "last_update_posted_date": "2026-04-29", "last_synced_at": "2026-09-25T01:16:23.597Z", "location_count": 1, "location_summary": "Fort Worth, Texas", "locations": [ { "city": "Fort Worth", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT05495087" }, { "nct_id": "NCT03433599", "title": "Repetitive Acute Intermittent Hypoxia for Spinal Cord Repair", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Spinal Cord Injuries" ], "interventions": [ { "name": "Repeated exposure to acute Intermittent Hypoxia (rAIH)", "type": "OTHER" }, { "name": "Normal Room Air", "type": "OTHER" }, { "name": "Upper-limb Training by Research Staff", "type": "OTHER" }, { "name": "Lower-limb Training by Research Staff", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Shirley Ryan AbilityLab", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 60, "start_date": "2020-04-09", "completion_date": "2025-12-28", "has_results": false, "last_update_posted_date": "2022-06-30", "last_synced_at": "2026-09-25T01:16:23.597Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT03433599" }, { "nct_id": "NCT06011876", "title": "BioFLO for Respiratory Recovery in SCI", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Spinal Cord Injuries" ], "interventions": [ { "name": "Acute Intermittent Hypoxia (AIH)", "type": "OTHER" }, { "name": "Acute Intermittent Hypercapnic-Hypoxia (AIHH)", "type": "OTHER" }, { "name": "Sham AIH", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "University of Florida", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 62, "start_date": "2023-12-21", "completion_date": "2027-09", "has_results": false, "last_update_posted_date": "2026-09-14", "last_synced_at": "2026-09-25T01:16:23.597Z", "location_count": 1, "location_summary": "Jacksonville, Florida", "locations": [ { "city": "Jacksonville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT06011876" }, { "nct_id": "NCT07135583", "title": "Non-Invasive Interventions for Respiratory Recovery in Chronic Spinal Cord Injury", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Spinal Cord Injury, Chronic", "Spinal Cord Injury Cervical", "Spinal Cord Injury Thoracic", "Incomplete Spinal Cord Injury" ], "interventions": [ { "name": "Active Comparator: Single Intervention 1", "type": "OTHER" }, { "name": "Active Comparator: Single Intervention 2", "type": "OTHER" }, { "name": "Respiratory Resistance Exercise", "type": "BEHAVIORAL" } ], "intervention_types": [ "OTHER", "BEHAVIORAL" ], "sponsor": "Thomas Jefferson University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 20, "start_date": "2025-09-18", "completion_date": "2027-08-15", "has_results": false, "last_update_posted_date": "2026-02-05", "last_synced_at": "2026-09-25T01:16:23.597Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT07135583" } ] }