{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=SIS+placement",
    "query": {
      "intervention": "SIS placement"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 9,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-03T22:54:55.966Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03520114",
      "title": "Retropubic vs. Single-Incision Mid-Urethral Sling for Stress Urinary Incontinence",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stress Urinary Incontinence",
        "Pelvic Floor Disorders"
      ],
      "interventions": [
        {
          "name": "RP sling placement",
          "type": "DEVICE"
        },
        {
          "name": "SIS placement",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "21 Years and older · Female only"
      },
      "enrollment_count": 280,
      "start_date": "2018-12-12",
      "completion_date": "2024-01-02",
      "has_results": true,
      "last_update_posted_date": "2025-01-16",
      "last_synced_at": "2026-09-03T22:54:55.966Z",
      "location_count": 6,
      "location_summary": "Washington D.C., District of Columbia • Chicago, Illinois • Manhasset, New York + 3 more",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Manhasset",
          "state": "New York"
        },
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03520114"
    },
    {
      "nct_id": "NCT02628873",
      "title": "Can SIS Using Air Bubbles Replace HSG for Fallopian Tubal Patency After Essure Placement",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Contraception"
      ],
      "interventions": [
        {
          "name": "HyCoSy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Wright State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 21,
      "start_date": "2015-12",
      "completion_date": "2018-10",
      "has_results": true,
      "last_update_posted_date": "2024-10-22",
      "last_synced_at": "2026-09-03T22:54:55.966Z",
      "location_count": 1,
      "location_summary": "Dayton, Ohio",
      "locations": [
        {
          "city": "Dayton",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02628873"
    },
    {
      "nct_id": "NCT01530126",
      "title": "Platelet Derived Growth Factor Stimulates Bone Fill and Rate of Attachment Level Gain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Periodontitis"
      ],
      "interventions": [
        {
          "name": "B-TCP + 0.3 mg/ml rhPDGF-BB in buffer",
          "type": "BIOLOGICAL"
        },
        {
          "name": "B-TCP + 1.0 mg/ml rhPDGF-BB in buffer",
          "type": "BIOLOGICAL"
        },
        {
          "name": "B-TCP +buffer",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "25 Years to 75 Years"
      },
      "enrollment_count": 180,
      "start_date": "2000-01",
      "completion_date": "2007-01",
      "has_results": false,
      "last_update_posted_date": "2016-01-08",
      "last_synced_at": "2026-09-03T22:54:55.966Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01530126"
    },
    {
      "nct_id": "NCT05774041",
      "title": "Visualization of the STN and GPi for DBS",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Deep Brain Stimulation",
        "Parkinson Disease"
      ],
      "interventions": [
        {
          "name": "SIS System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Surgical Information Sciences Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 80,
      "start_date": "2023-10-19",
      "completion_date": "2025-04-07",
      "has_results": false,
      "last_update_posted_date": "2025-04-25",
      "last_synced_at": "2026-09-03T22:54:55.966Z",
      "location_count": 10,
      "location_summary": "Tucson, Arizona • Little Rock, Arkansas • Hartford, Connecticut + 7 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Hartford",
          "state": "Connecticut"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05774041"
    },
    {
      "nct_id": "NCT03304626",
      "title": "Budesonide for Liver Transplant Immune Suppression",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Acute Cellular Graft Rejection",
        "New Onset Diabetes After Transplant"
      ],
      "interventions": [
        {
          "name": "Budesonide 3Mg Capsule",
          "type": "DRUG"
        },
        {
          "name": "Standard of Care Prednisone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "21 Years to 75 Years"
      },
      "enrollment_count": 40,
      "start_date": "2017-06-27",
      "completion_date": "2019-12-31",
      "has_results": true,
      "last_update_posted_date": "2021-07-20",
      "last_synced_at": "2026-09-03T22:54:55.966Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03304626"
    },
    {
      "nct_id": "NCT01272284",
      "title": "The Altis® Single Incision Sling System for Female Stress Urinary Incontinence Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stress Urinary Incontinence"
      ],
      "interventions": [
        {
          "name": "Altis® Single Incision Sling System (SIS)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Coloplast A/S",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 113,
      "start_date": "2010-12",
      "completion_date": "2014-01",
      "has_results": true,
      "last_update_posted_date": "2021-02-11",
      "last_synced_at": "2026-09-03T22:54:55.966Z",
      "location_count": 16,
      "location_summary": "Murrieta, California • Hialeah, Florida • Alpharetta, Georgia + 12 more",
      "locations": [
        {
          "city": "Murrieta",
          "state": "California"
        },
        {
          "city": "Hialeah",
          "state": "Florida"
        },
        {
          "city": "Alpharetta",
          "state": "Georgia"
        },
        {
          "city": "Idaho Falls",
          "state": "Idaho"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01272284"
    },
    {
      "nct_id": "NCT04964466",
      "title": "Release Kinetics in PRF Versus GEM21S With and Without Bone Substitutes: An In Vitro Analysis",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Bone Loss"
      ],
      "interventions": [
        {
          "name": "Amount of PDGF-BB in PRF preparation vs. GEM21",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Amount of PDGF-BB available in PRF + bone substitutes vs. rhPDGF-BB+ bone substitutes following preparation",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Release kinetics of PDGF-BB in PRF + bone substitutes vs. rhPDGF-BB + bone substitutes",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Release kinetics of PDGF-BB in rhPDGF-BB + PRF + bone substitutes",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 5,
      "start_date": "2021-08-31",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2025-12-02",
      "last_synced_at": "2026-09-03T22:54:55.966Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04964466"
    },
    {
      "nct_id": "NCT03752619",
      "title": "Peripheral Nerve Stimulation(PNS) for Subacromial Impingement Syndrome(SIS)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Shoulder Pain",
        "Shoulder Impingement Syndrome",
        "Shoulder Tendinitis",
        "Shoulder Bursitis",
        "Pain, Shoulder"
      ],
      "interventions": [
        {
          "name": "Contracting Producing Peripheral Nerve Stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Non Contracting Producing Peripheral Nerve Stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Physical Therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "MetroHealth Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "21 Years to 100 Years"
      },
      "enrollment_count": 116,
      "start_date": "2019-03-01",
      "completion_date": "2024-06-21",
      "has_results": true,
      "last_update_posted_date": "2025-06-17",
      "last_synced_at": "2026-09-03T22:54:55.966Z",
      "location_count": 2,
      "location_summary": "Cleveland, Ohio • Dallas, Texas",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03752619"
    },
    {
      "nct_id": "NCT04586166",
      "title": "Single-incision Versus Retropubic Mid-Urethral Sling (Solyx) for SUI During Minimally Invasive Sacrocolpopexy",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stress Urinary Incontinence",
        "Pelvic Floor Disorders"
      ],
      "interventions": [
        {
          "name": "RP Sling",
          "type": "DEVICE"
        },
        {
          "name": "SIS",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "21 Years and older · Female only"
      },
      "enrollment_count": 180,
      "start_date": "2020-12-23",
      "completion_date": "2032-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-02",
      "last_synced_at": "2026-09-03T22:54:55.966Z",
      "location_count": 5,
      "location_summary": "Coconut Creek, Florida • Augusta, Georgia • Chicago, Illinois + 1 more",
      "locations": [
        {
          "city": "Coconut Creek",
          "state": "Florida"
        },
        {
          "city": "Augusta",
          "state": "Georgia"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04586166"
    }
  ]
}