{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Saline+%2B+exercise&page=2",
    "query": {
      "intervention": "Saline + exercise",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 86,
    "total_pages": 9,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Saline+%2B+exercise&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Saline+%2B+exercise&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-01T06:59:31.827Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05901233",
      "title": "Speech-Language Treatment With Remotely Supervised Transcranial Direct Current Stimulation in Primary Progressive Aphasia",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Primary Progressive Aphasia"
      ],
      "interventions": [
        {
          "name": "Remotely supervised Transcranial Direct Current Stimulation (RS-tDCS)",
          "type": "DEVICE"
        },
        {
          "name": "Remotely supervised sham tDCS (RS-sham-tDCS)",
          "type": "DEVICE"
        },
        {
          "name": "Lexical Retrieval Training (LRT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Video Implemented Script Training in Aphasia (VISTA)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Texas at Austin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 10,
      "start_date": "2023-07-10",
      "completion_date": "2026-09-30",
      "has_results": false,
      "last_update_posted_date": "2025-10-08",
      "last_synced_at": "2026-10-01T06:59:31.827Z",
      "location_count": 2,
      "location_summary": "San Francisco, California • Austin, Texas",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05901233"
    },
    {
      "nct_id": "NCT01547130",
      "title": "Yoga and Bolus Lukewarm Saline as Rapid Colonoscopy Preparation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Colonic Neoplasms"
      ],
      "interventions": [
        {
          "name": "Normal (0.9%) saline",
          "type": "DRUG"
        },
        {
          "name": "HalfLytely",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Arya, Vijaypal, M.D., P.C.",
      "sponsor_class": "INDIV",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "21 Years to 70 Years"
      },
      "enrollment_count": 133,
      "start_date": "2008-05",
      "completion_date": "2011-01",
      "has_results": true,
      "last_update_posted_date": "2015-03-04",
      "last_synced_at": "2026-10-01T06:59:31.827Z",
      "location_count": 1,
      "location_summary": "Middle Village, New York",
      "locations": [
        {
          "city": "Middle Village",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01547130"
    },
    {
      "nct_id": "NCT02580604",
      "title": "PTH And Calcium Responses to Exercise in Older Adults Experiment 2 (PACE Sr. 2)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoporosis"
      ],
      "interventions": [
        {
          "name": "Calcium Chloride/Calcium Gluconate",
          "type": "DRUG"
        },
        {
          "name": "Half-Normal Saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "80 Years",
        "sex": "FEMALE",
        "summary": "60 Years to 80 Years · Female only"
      },
      "enrollment_count": 12,
      "start_date": "2015-11",
      "completion_date": "2025-07-31",
      "has_results": true,
      "last_update_posted_date": "2025-08-13",
      "last_synced_at": "2026-10-01T06:59:31.827Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02580604"
    },
    {
      "nct_id": "NCT06305780",
      "title": "RECOVER-AUTONOMIC Platform Protocol",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Long COVID",
        "Long Covid19",
        "Long Covid-19"
      ],
      "interventions": [
        {
          "name": "IVIG + Coordinated Care",
          "type": "DRUG"
        },
        {
          "name": "IVIG Placebo + Coordinated Care",
          "type": "DRUG"
        },
        {
          "name": "Ivabradine + Coordinated Care",
          "type": "DRUG"
        },
        {
          "name": "Ivabradine Placebo + Coordinated Care",
          "type": "DRUG"
        },
        {
          "name": "IVIG + Usual Care",
          "type": "DRUG"
        },
        {
          "name": "IVIG Placebo + Usual Care",
          "type": "DRUG"
        },
        {
          "name": "Ivabradine + Usual Care",
          "type": "DRUG"
        },
        {
          "name": "Ivabradine Placebo + Usual Care",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Kanecia Obie Zimmerman",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 381,
      "start_date": "2024-03-11",
      "completion_date": "2025-07-09",
      "has_results": true,
      "last_update_posted_date": "2026-08-03",
      "last_synced_at": "2026-10-01T06:59:31.827Z",
      "location_count": 50,
      "location_summary": "Opelika, Alabama • Phoenix, Arizona • Little Rock, Arkansas + 45 more",
      "locations": [
        {
          "city": "Opelika",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06305780"
    },
    {
      "nct_id": "NCT02116946",
      "title": "Plasma Injections Plus Exercise for Patellar Tendinopathy",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Patellar Tendinopathy"
      ],
      "interventions": [
        {
          "name": "Platelet Rich Plasma (PRP)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Saline + exercise",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "University of British Columbia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 64,
      "start_date": "2014-03",
      "completion_date": "2018-12",
      "has_results": false,
      "last_update_posted_date": "2018-12-21",
      "last_synced_at": "2026-10-01T06:59:31.827Z",
      "location_count": 2,
      "location_summary": "Vail, Colorado • Seattle, Washington",
      "locations": [
        {
          "city": "Vail",
          "state": "Colorado"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02116946"
    },
    {
      "nct_id": "NCT06132412",
      "title": "Transcranial Direct Current Stimulation in Conjunction With Individualized Physical Therapy for Individuals With Chronic Knee Pain",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Pain Chronic"
      ],
      "interventions": [
        {
          "name": "transcranial direct current stimulation",
          "type": "DEVICE"
        },
        {
          "name": "physical therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "University of Illinois at Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2024-06-06",
      "completion_date": "2026-12-01",
      "has_results": false,
      "last_update_posted_date": "2026-05-11",
      "last_synced_at": "2026-10-01T06:59:31.827Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06132412"
    },
    {
      "nct_id": "NCT05195931",
      "title": "Cardiac Output in Heart Failure Patients With Mechanical Pumps",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Heart Failure, Systolic",
        "Mechanical Circulatory Support",
        "Cardiovascular Hemodynamics"
      ],
      "interventions": [
        {
          "name": "preload challenge",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "afterload challenge",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "contractility assessment",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 7,
      "start_date": "2021-06-08",
      "completion_date": "2022-08-25",
      "has_results": false,
      "last_update_posted_date": "2023-05-19",
      "last_synced_at": "2026-10-01T06:59:31.827Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05195931"
    },
    {
      "nct_id": "NCT04595890",
      "title": "Knee Injections for the Clinical Management of Knee OsteoArthritis",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Arthrex Angel System used to prepare injection of Bone Marrow Concentrate (BMC)",
          "type": "DEVICE"
        },
        {
          "name": "Saline injection",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "University of Delaware",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "79 Years",
        "sex": "ALL",
        "summary": "40 Years to 79 Years"
      },
      "enrollment_count": 0,
      "start_date": "2022-09-01",
      "completion_date": "2024-09-01",
      "has_results": false,
      "last_update_posted_date": "2023-10-02",
      "last_synced_at": "2026-10-01T06:59:31.827Z",
      "location_count": 1,
      "location_summary": "Newark, Delaware",
      "locations": [
        {
          "city": "Newark",
          "state": "Delaware"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04595890"
    },
    {
      "nct_id": "NCT01921569",
      "title": "Micronized Dehydrated Human Amniotic Membrane Suspension in the Treatment of Lateral Epicondylitis",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Epicondylitis, Lateral Humeral"
      ],
      "interventions": [
        {
          "name": "Standard of Care Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "dHACM Injection",
          "type": "OTHER"
        },
        {
          "name": "Normal Saline Injection",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "MiMedx Group, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 5,
      "start_date": "2013-06",
      "completion_date": "2014-03",
      "has_results": false,
      "last_update_posted_date": "2015-09-24",
      "last_synced_at": "2026-10-01T06:59:31.827Z",
      "location_count": 1,
      "location_summary": "Sharonville, Ohio",
      "locations": [
        {
          "city": "Sharonville",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01921569"
    },
    {
      "nct_id": "NCT04292535",
      "title": "Safety and Efficacy of Combining Intranasal Insulin & Acute Exercise",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Insulin",
        "Exercise"
      ],
      "interventions": [
        {
          "name": "Placebo into the intranasal mucosa",
          "type": "DRUG"
        },
        {
          "name": "20 IU NovoLog Insulin aspart into the intranasal mucosa",
          "type": "DRUG"
        },
        {
          "name": "40 IU NovoLog Insulin aspart into the intranasal mucosa",
          "type": "DRUG"
        },
        {
          "name": "60 IU NovoLog Insulin aspart into the intranasal mucosa",
          "type": "DRUG"
        },
        {
          "name": "80 IU NovoLog Insulin aspart into the intranasal mucosa",
          "type": "DRUG"
        },
        {
          "name": "100 IU NovoLog Insulin aspart into the intranasal mucosa",
          "type": "DRUG"
        },
        {
          "name": "120 IU NovoLog Insulin aspart into the intranasal mucosa",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Michigan State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 116,
      "start_date": "2018-06-15",
      "completion_date": "2020-02-20",
      "has_results": true,
      "last_update_posted_date": "2021-06-21",
      "last_synced_at": "2026-10-01T06:59:31.827Z",
      "location_count": 1,
      "location_summary": "East Lansing, Michigan",
      "locations": [
        {
          "city": "East Lansing",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04292535"
    }
  ]
}