{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Saline+Nasal+Irrigation&page=3",
    "query": {
      "intervention": "Saline Nasal Irrigation",
      "page": 3
    },
    "page_size": 10
  },
  "pagination": {
    "page": 3,
    "page_size": 10,
    "total_count": 166,
    "total_pages": 17,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Saline+Nasal+Irrigation&page=4&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Saline+Nasal+Irrigation&page=2&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-08T23:37:24.047Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02728505",
      "title": "SinuSurf vs. Saline Solution in Normal Subjects",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Rhinosinusitis"
      ],
      "interventions": [
        {
          "name": "SinuSurf irrigation twice daily",
          "type": "DRUG"
        },
        {
          "name": "NeilMed Sinus rinse irrigation twice daily",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 40,
      "start_date": "2016-04-12",
      "completion_date": "2017-01-20",
      "has_results": false,
      "last_update_posted_date": "2017-03-14",
      "last_synced_at": "2026-10-08T23:37:24.047Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02728505"
    },
    {
      "nct_id": "NCT01897545",
      "title": "Combined Treatment of Arterial Hypertension and Atrial Fibrillation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Arterial Hypertension",
        "Atrial Fibrillation"
      ],
      "interventions": [
        {
          "name": "Circumferential PV isolation",
          "type": "PROCEDURE"
        },
        {
          "name": "PV isolation+renal denervation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Meshalkin Research Institute of Pathology of Circulation",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 60,
      "start_date": "2012-04",
      "completion_date": "2013-06",
      "has_results": false,
      "last_update_posted_date": "2013-10-09",
      "last_synced_at": "2026-10-08T23:37:24.047Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01897545"
    },
    {
      "nct_id": "NCT03729830",
      "title": "Prospective Evaluation of Open Irrigated Ablation Catheters With High Resolution Mapping to Treat Paroxysmal Atrial Fibrillation",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Paroxysmal Atrial Fibrillation"
      ],
      "interventions": [
        {
          "name": "Boston Scientific Open Irrigated Ablation Catheters",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Boston Scientific Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "20 Years and older"
      },
      "enrollment_count": 415,
      "start_date": "2019-03-04",
      "completion_date": "2024-05-03",
      "has_results": true,
      "last_update_posted_date": "2026-01-21",
      "last_synced_at": "2026-10-08T23:37:24.047Z",
      "location_count": 18,
      "location_summary": "Birmingham, Alabama • Torrance, California • Miami, Florida + 15 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Torrance",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Boise",
          "state": "Idaho"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03729830"
    },
    {
      "nct_id": "NCT01048307",
      "title": "Effect of Prontosan Wound Irrigation Solution on Venous Ulcers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Wound Care",
        "Venous Ulcer Care",
        "Wound Cleansing",
        "Chronic Wound Care"
      ],
      "interventions": [
        {
          "name": "Prontosan wound irrigation solution",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Calvary Hospital, Bronx, NY",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "95 Years",
        "sex": "ALL",
        "summary": "18 Years to 95 Years"
      },
      "enrollment_count": 20,
      "start_date": "2009-06",
      "completion_date": "2010-07",
      "has_results": false,
      "last_update_posted_date": "2010-08-17",
      "last_synced_at": "2026-10-08T23:37:24.047Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01048307"
    },
    {
      "nct_id": "NCT05659524",
      "title": "Nasal Outcomes Using Saline Irrigations After Endonasal Pituitary Surgery",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pituitary Tumor"
      ],
      "interventions": [
        {
          "name": "Nasal saline irrigation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Lori Wood",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "19 Years to 85 Years"
      },
      "enrollment_count": 140,
      "start_date": "2020-12-18",
      "completion_date": "2029-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-04-19",
      "last_synced_at": "2026-10-08T23:37:24.047Z",
      "location_count": 2,
      "location_summary": "Phoenix, Arizona • Cleveland, Ohio",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05659524"
    },
    {
      "nct_id": "NCT00435994",
      "title": "Assessment of Airway Obstruction in Infants With Lower Respiratory Infections",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bronchiolitis",
        "Respiratory Syncytial Virus Infections"
      ],
      "interventions": [
        {
          "name": "Inhaled primatene will be given as a breathing treatment",
          "type": "DRUG"
        },
        {
          "name": "Nasal Washing",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "2 Months",
        "maximum_age": "2 Years",
        "sex": "ALL",
        "summary": "2 Months to 2 Years"
      },
      "enrollment_count": 59,
      "start_date": "2003-12",
      "completion_date": "2012-12",
      "has_results": true,
      "last_update_posted_date": "2016-06-01",
      "last_synced_at": "2026-10-08T23:37:24.047Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00435994"
    },
    {
      "nct_id": "NCT07518901",
      "title": "Nanozymes in Endodontics",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Apical Periodontitis",
        "Endodontic Disease",
        "Root Canal Infection"
      ],
      "interventions": [
        {
          "name": "Nanozyme treatment",
          "type": "DRUG"
        },
        {
          "name": "Control (Standard treatment)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 72,
      "start_date": "2026-08-24",
      "completion_date": "2028-06",
      "has_results": false,
      "last_update_posted_date": "2026-08-31",
      "last_synced_at": "2026-10-08T23:37:24.047Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07518901"
    },
    {
      "nct_id": "NCT04802408",
      "title": "SARS-Cov-2 (COVID-19) Nasal Pharyngeal and Oral Pharyngeal Wash (SNOW) Trial",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Covid19",
        "SARS-CoV Infection"
      ],
      "interventions": [
        {
          "name": "Shampoo and saline",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Saline and Listerine",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Shampoo and Listerine",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Saline and Saline",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Milton S. Hershey Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 171,
      "start_date": "2021-10-01",
      "completion_date": "2024-05-30",
      "has_results": false,
      "last_update_posted_date": "2026-09-14",
      "last_synced_at": "2026-10-08T23:37:24.047Z",
      "location_count": 2,
      "location_summary": "Hershey, Pennsylvania • State College, Pennsylvania",
      "locations": [
        {
          "city": "Hershey",
          "state": "Pennsylvania"
        },
        {
          "city": "State College",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04802408"
    },
    {
      "nct_id": "NCT05897086",
      "title": "Polyethylene-glycol Assisted Nerve Repair in Phalloplasty",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Gender Dysphoria"
      ],
      "interventions": [
        {
          "name": "Polyethylene Glycol 3350",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 30,
      "start_date": "2023-08-01",
      "completion_date": "2029-12-01",
      "has_results": false,
      "last_update_posted_date": "2025-10-20",
      "last_synced_at": "2026-10-08T23:37:24.047Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05897086"
    },
    {
      "nct_id": "NCT03502499",
      "title": "Half-normal Saline in Idiopathic Left Ventricular Outflow Tract Arrhythmias Ablation",
      "overall_status": "SUSPENDED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ventricular Arrythmia"
      ],
      "interventions": [
        {
          "name": "Half-normal saline",
          "type": "DRUG"
        },
        {
          "name": "Normal saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Texas Cardiac Arrhythmia Research Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 50,
      "start_date": "2018-05-16",
      "completion_date": "2022-04",
      "has_results": false,
      "last_update_posted_date": "2022-04-11",
      "last_synced_at": "2026-10-08T23:37:24.047Z",
      "location_count": 2,
      "location_summary": "Aurora, Colorado • Austin, Texas",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03502499"
    }
  ]
}