{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sam+Ultrasonic+Diathermy+Device",
    "query": {
      "intervention": "Sam Ultrasonic Diathermy Device"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 13,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sam+Ultrasonic+Diathermy+Device&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-13T20:35:57.327Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04391842",
      "title": "Sustained Acoustic Medicine (SAM) Combined With a Diclofenac Ultrasound Coupling Patch for Knee Osteoarthritis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Osteo Arthritis Knee",
        "Arthritis"
      ],
      "interventions": [
        {
          "name": "Sustained Acoustic Device with 1% Diclofenac patch",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "ZetrOZ, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "45 Years to 85 Years"
      },
      "enrollment_count": 34,
      "start_date": "2019-09-01",
      "completion_date": "2019-12-31",
      "has_results": true,
      "last_update_posted_date": "2023-06-27",
      "last_synced_at": "2026-09-13T20:35:57.327Z",
      "location_count": 1,
      "location_summary": "Dryden, New York",
      "locations": [
        {
          "city": "Dryden",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04391842"
    },
    {
      "nct_id": "NCT05254574",
      "title": "Sustained Acoustic Medicine for Osteoarthritis Pain",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Sustained Acoustic Device with 2.5% Diclofenac Patch",
          "type": "DEVICE"
        },
        {
          "name": "2.5% Diclofenac Patches",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "ZetrOZ, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "35 Years to 85 Years"
      },
      "enrollment_count": 200,
      "start_date": "2022-02-14",
      "completion_date": "2026-05-31",
      "has_results": false,
      "last_update_posted_date": "2025-02-27",
      "last_synced_at": "2026-09-13T20:35:57.327Z",
      "location_count": 1,
      "location_summary": "Tampa, Florida",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05254574"
    },
    {
      "nct_id": "NCT02466308",
      "title": "Long Duration Therapeutic Ultrasound for Tendon Healing",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tendinopathy",
        "Tendinitis",
        "Tendinosis"
      ],
      "interventions": [
        {
          "name": "SAM Ultrasound Diathermy Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "ZetrOZ, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 28,
      "start_date": "2014-02",
      "completion_date": "2014-09",
      "has_results": false,
      "last_update_posted_date": "2017-01-31",
      "last_synced_at": "2026-09-13T20:35:57.327Z",
      "location_count": 1,
      "location_summary": "Trumbull, Connecticut",
      "locations": [
        {
          "city": "Trumbull",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02466308"
    },
    {
      "nct_id": "NCT01993693",
      "title": "Wearable Therapeutic Ultrasound Study for Knee Osteoarthritis",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Ultrasonic Diathermy Device",
          "type": "DEVICE"
        },
        {
          "name": "Sham Ultrasonic Diathermy Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "ZetrOZ, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "35 Years to 80 Years"
      },
      "enrollment_count": 15,
      "start_date": "2012-10",
      "completion_date": "2014-07",
      "has_results": false,
      "last_update_posted_date": "2015-11-18",
      "last_synced_at": "2026-09-13T20:35:57.327Z",
      "location_count": 1,
      "location_summary": "East Syracuse, New York",
      "locations": [
        {
          "city": "East Syracuse",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01993693"
    },
    {
      "nct_id": "NCT02135094",
      "title": "Low Intensity Ultrasound Therapy for Upper Back Pain Relief",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Muscle Spasm"
      ],
      "interventions": [
        {
          "name": "Active ultrasound therapy device",
          "type": "DEVICE"
        },
        {
          "name": "Placebo ultrasound therapy device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "ZetrOZ, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 33,
      "start_date": "2014-06",
      "completion_date": "2015-09",
      "has_results": true,
      "last_update_posted_date": "2020-04-02",
      "last_synced_at": "2026-09-13T20:35:57.327Z",
      "location_count": 1,
      "location_summary": "Trumbull, Connecticut",
      "locations": [
        {
          "city": "Trumbull",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02135094"
    },
    {
      "nct_id": "NCT05259995",
      "title": "Sustained Acoustic Medicine Ultrasound Diathermy Clinical Performance",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Measurement of Diathermy on Anatomical Locations of the Body"
      ],
      "interventions": [
        {
          "name": "Sustained Acoustic Medicine",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "ZetrOZ, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 54,
      "start_date": "2022-02-21",
      "completion_date": "2022-06-30",
      "has_results": false,
      "last_update_posted_date": "2023-02-21",
      "last_synced_at": "2026-09-13T20:35:57.327Z",
      "location_count": 1,
      "location_summary": "Trumbull, Connecticut",
      "locations": [
        {
          "city": "Trumbull",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05259995"
    },
    {
      "nct_id": "NCT06510062",
      "title": "Comparative Evaluation of Sustained Acoustic Medicine Device on Circulation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Measurement of Circulation on Anatomical Locations of the Body"
      ],
      "interventions": [
        {
          "name": "Sustained Acoustic Medicine",
          "type": "DEVICE"
        },
        {
          "name": "2.5% Diclofenac Patches",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "ZetrOZ, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 67,
      "start_date": "2024-07-22",
      "completion_date": "2024-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-03-06",
      "last_synced_at": "2026-09-13T20:35:57.327Z",
      "location_count": 1,
      "location_summary": "Trumbull, Connecticut",
      "locations": [
        {
          "city": "Trumbull",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06510062"
    },
    {
      "nct_id": "NCT05882812",
      "title": "Sustained Acoustic Medicine (SAM) for Symptomatic Treatment of Knee Pain Related to Osteoarthritis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Osteo Arthritis Knee",
        "Arthritis"
      ],
      "interventions": [
        {
          "name": "Sustained Acoustic Device with 2.5% Diclofenac Patch",
          "type": "DEVICE"
        },
        {
          "name": "Sustained Acoustic Device with 0% Diclofenac Patch",
          "type": "DEVICE"
        },
        {
          "name": "2.5% Diclofenac Patches",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "ZetrOZ, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "35 Years to 80 Years"
      },
      "enrollment_count": 200,
      "start_date": "2023-06-03",
      "completion_date": "2024-02-22",
      "has_results": true,
      "last_update_posted_date": "2025-05-15",
      "last_synced_at": "2026-09-13T20:35:57.327Z",
      "location_count": 3,
      "location_summary": "Stamford, Connecticut • Trumbull, Connecticut • Dryden, New York",
      "locations": [
        {
          "city": "Stamford",
          "state": "Connecticut"
        },
        {
          "city": "Trumbull",
          "state": "Connecticut"
        },
        {
          "city": "Dryden",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05882812"
    },
    {
      "nct_id": "NCT05883241",
      "title": "Sustained Acoustic Medicine (SAM) for Symptomatic Treatment of Pain Related to Bone Fracture",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Bone Fracture",
        "Fresh Fracture"
      ],
      "interventions": [
        {
          "name": "Sustained Acoustic Device with 2.5% Diclofenac Patch",
          "type": "DEVICE"
        },
        {
          "name": "2.5% Diclofenac Patches",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "ZetrOZ, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 90,
      "start_date": "2023-06-01",
      "completion_date": "2026-02-28",
      "has_results": false,
      "last_update_posted_date": "2025-02-28",
      "last_synced_at": "2026-09-13T20:35:57.327Z",
      "location_count": 2,
      "location_summary": "Trumbull, Connecticut • Lansdowne, Virginia",
      "locations": [
        {
          "city": "Trumbull",
          "state": "Connecticut"
        },
        {
          "city": "Lansdowne",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05883241"
    },
    {
      "nct_id": "NCT05050448",
      "title": "Comparative Usability Evaluation of Sustained Acoustic Medicine (SAM) Devices and Topical Gel for OA Knee Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Knee Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Sustained Acoustic Device with 2.5% Diclofenac Patch",
          "type": "DEVICE"
        },
        {
          "name": "1% Diclofenac Topical Gel",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "ZetrOZ, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "35 Years to 80 Years"
      },
      "enrollment_count": 60,
      "start_date": "2021-08-01",
      "completion_date": "2022-12-31",
      "has_results": true,
      "last_update_posted_date": "2025-05-02",
      "last_synced_at": "2026-09-13T20:35:57.327Z",
      "location_count": 3,
      "location_summary": "Stamford, Connecticut • Trumbull, Connecticut • Dryden, New York",
      "locations": [
        {
          "city": "Stamford",
          "state": "Connecticut"
        },
        {
          "city": "Trumbull",
          "state": "Connecticut"
        },
        {
          "city": "Dryden",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05050448"
    }
  ]
}