{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Selective+Serotonin+Uptake+Inhibitor+%28SSRI%29&page=6", "query": { "intervention": "Selective Serotonin Uptake Inhibitor (SSRI)", "page": 6 }, "page_size": 10 }, "pagination": { "page": 6, "page_size": 10, "total_count": 124, "total_pages": 13, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Selective+Serotonin+Uptake+Inhibitor+%28SSRI%29&page=7&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Selective+Serotonin+Uptake+Inhibitor+%28SSRI%29&page=5&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-12T01:44:08.097Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT06049797", "title": "A Study Following Women in Menopause Treated With a Non-hormonal Therapy for Hot Flashes and Night Sweats", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Hot Flashes" ], "interventions": [ { "name": "Fezolinetant", "type": "DRUG" }, { "name": "Paroxetine", "type": "DRUG" }, { "name": "Citalopram", "type": "DRUG" }, { "name": "Escitalopram", "type": "DRUG" }, { "name": "Desvenlafaxine", "type": "DRUG" }, { "name": "Venlafaxine", "type": "DRUG" }, { "name": "Gabapentin", "type": "DRUG" }, { "name": "Clonidine", "type": "DRUG" }, { "name": "Pregabalin", "type": "DRUG" }, { "name": "Oxybutynin", "type": "DRUG" }, { "name": "Any other SSRI/SNRI not already specified", "type": "DRUG" }, { "name": "Any other non-hormonal pharmacologic therapy prescribed for the treatment of VMS not included in a category above", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Astellas Pharma Global Development, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": "75 Years", "sex": "FEMALE", "summary": "40 Years to 75 Years · Female only" }, "enrollment_count": 999, "start_date": "2023-11-15", "completion_date": "2026-05-07", "has_results": false, "last_update_posted_date": "2026-06-05", "last_synced_at": "2026-10-12T01:44:08.097Z", "location_count": 48, "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Lomita, California + 39 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Lomita", "state": "California" }, { "city": "Pomona", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06049797" }, { "nct_id": "NCT01579942", "title": "Potential Use Of Brain Network Activation Analysis to Diagnose Major Depression", "overall_status": "TERMINATED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Major Depressive Disorder" ], "interventions": [], "intervention_types": [], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 70, "start_date": "2012-04", "completion_date": null, "has_results": false, "last_update_posted_date": "2017-03-06", "last_synced_at": "2026-10-12T01:44:08.097Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT01579942" }, { "nct_id": "NCT01254305", "title": "Safety and Efficacy of Levomilnacipran ER (F2695 SR) in Adults With Fatigue Associated With Major Depressive Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Major Depressive Disorder" ], "interventions": [ { "name": "Levomilnacipran ER", "type": "DRUG" }, { "name": "Paroxetine, Sertraline, Citalopram or Fluoxetine.", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Forest Laboratories", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 262, "start_date": "2011-04", "completion_date": "2012-07", "has_results": true, "last_update_posted_date": "2014-08-06", "last_synced_at": "2026-10-12T01:44:08.097Z", "location_count": 20, "location_summary": "Birmingham, Alabama • Little Rock, Arkansas • Cerritos, California + 17 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Cerritos", "state": "California" }, { "city": "Fort Myers", "state": "Florida" }, { "city": "Jacksonville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT01254305" }, { "nct_id": "NCT01185340", "title": "A Study in Participants With Major Depressive Disorder Who Are Partial Responders to Selective Serotonin Reuptake Inhibitor", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Major Depressive Disorder" ], "interventions": [ { "name": "LY2216684", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "SSRI", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eli Lilly and Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1056, "start_date": "2011-03", "completion_date": "2013-04", "has_results": true, "last_update_posted_date": "2018-04-27", "last_synced_at": "2026-10-12T01:44:08.097Z", "location_count": 20, "location_summary": "Garden Grove, California • Oakland, California • Temecula, California + 17 more", "locations": [ { "city": "Garden Grove", "state": "California" }, { "city": "Oakland", "state": "California" }, { "city": "Temecula", "state": "California" }, { "city": "Waterbury", "state": "Connecticut" }, { "city": "Boca Raton", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT01185340" }, { "nct_id": "NCT00118417", "title": "Therapies for Treatment-Resistant Panic Disorder Symptoms", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Panic Disorder" ], "interventions": [ { "name": "Clonazepam", "type": "DRUG" }, { "name": "Sertraline", "type": "DRUG" }, { "name": "Cognitive behavioral therapy", "type": "BEHAVIORAL" } ], "intervention_types": [ "DRUG", "BEHAVIORAL" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 46, "start_date": "1999-03", "completion_date": "2007-10", "has_results": true, "last_update_posted_date": "2014-06-11", "last_synced_at": "2026-10-12T01:44:08.097Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00118417" }, { "nct_id": "NCT00086307", "title": "Lexapro and Pramipexole and to Treat Major Depression", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Major Depression" ], "interventions": [ { "name": "Pramipexole", "type": "DRUG" }, { "name": "Escitalopram", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Mental Health (NIMH)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 39, "start_date": "2004-06", "completion_date": "2010-03", "has_results": true, "last_update_posted_date": "2013-01-28", "last_synced_at": "2026-10-12T01:44:08.097Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00086307" }, { "nct_id": "NCT04437485", "title": "eIMPACT-DM Pilot Trial: Depression Treatment to Reduce Diabetes Risk", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Depression", "Major Depressive Disorder", "Dysthymic Disorder", "Depressive Symptoms", "Type 2 Diabetes", "PreDiabetes", "Insulin Resistance" ], "interventions": [ { "name": "Good Days Ahead (GDA)", "type": "BEHAVIORAL" }, { "name": "Problem Solving Treatment in Primary Care (PST-PC)", "type": "BEHAVIORAL" }, { "name": "Antidepressant Medications", "type": "DRUG" }, { "name": "Active Control", "type": "OTHER" } ], "intervention_types": [ "BEHAVIORAL", "DRUG", "OTHER" ], "sponsor": "Indiana University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 46, "start_date": "2020-10-14", "completion_date": "2022-08-29", "has_results": true, "last_update_posted_date": "2023-11-02", "last_synced_at": "2026-10-12T01:44:08.097Z", "location_count": 1, "location_summary": "Indianapolis, Indiana", "locations": [ { "city": "Indianapolis", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT04437485" }, { "nct_id": "NCT04748276", "title": "Tracking Response to Antidepressants in Advance of Investigational Trials", "overall_status": "UNKNOWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Major Depressive Disorder" ], "interventions": [ { "name": "FDA-approved selective-serotonin reuptake inhibitors (SSRIs) and selective-norepinephrine reuptake inhibitors (SNRIs)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Adams Clinical", "sponsor_class": "NETWORK", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 400, "start_date": "2019-01-02", "completion_date": "2023-12-31", "has_results": false, "last_update_posted_date": "2023-03-27", "last_synced_at": "2026-10-12T01:44:08.097Z", "location_count": 1, "location_summary": "Watertown, Massachusetts", "locations": [ { "city": "Watertown", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT04748276" }, { "nct_id": "NCT06328140", "title": "Sleep Quality, Cognitive Performance, and Computerized Cognitive Training", "overall_status": "WITHDRAWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Bipolar Disorder", "Major Depressive Disorder", "Psychosis" ], "interventions": [ { "name": "Lurasidone", "type": "DRUG" }, { "name": "FDA Approved antidepressant treatment", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "George West Mental Health Foundation d/b/a Skyland Trail", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 0, "start_date": "2024-04-15", "completion_date": "2025-01-22", "has_results": false, "last_update_posted_date": "2025-05-04", "last_synced_at": "2026-10-12T01:44:08.097Z", "location_count": 1, "location_summary": "Atlanta, Georgia", "locations": [ { "city": "Atlanta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT06328140" }, { "nct_id": "NCT02307617", "title": "Glutamate Probes in Adolescent Depression", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Major Depressive Disorder", "Major Depressive Disorder, Recurrent", "Major Depressive Disorder, Remitted" ], "interventions": [], "intervention_types": [], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "13 Years", "maximum_age": "21 Years", "sex": "ALL", "summary": "13 Years to 21 Years" }, "enrollment_count": 57, "start_date": "2014-08-01", "completion_date": "2017-04-17", "has_results": false, "last_update_posted_date": "2021-04-23", "last_synced_at": "2026-10-12T01:44:08.097Z", "location_count": 1, "location_summary": "Rochester, Minnesota", "locations": [ { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT02307617" } ] }