{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sertraline+Matching+Placebo&page=2", "query": { "intervention": "Sertraline Matching Placebo", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sertraline+Matching+Placebo&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-09-29T09:04:07.718Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00177424", "title": "Sertraline for Preventing Post-stroke Depression and Improving Rehabilitation Outcomes", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Cerebrovascular Accident", "Depression" ], "interventions": [ { "name": "sertraline", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Pittsburgh", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": null, "sex": "ALL", "summary": "40 Years and older" }, "enrollment_count": 154, "start_date": "2004-07", "completion_date": "2007-10", "has_results": false, "last_update_posted_date": "2014-06-27", "last_synced_at": "2026-09-29T09:04:07.718Z", "location_count": 1, "location_summary": "Pittsburgh, Pennsylvania", "locations": [ { "city": "Pittsburgh", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT00177424" }, { "nct_id": "NCT00701675", "title": "Pharmacological Treatment of Generalized Anxiety Disorder in the Elderly", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Generalized Anxiety Disorder" ], "interventions": [ { "name": "sertraline 50 mg daily", "type": "DRUG" }, { "name": "sertraline 100 mg daily", "type": "DRUG" }, { "name": "Placebo 50 or 100 mg", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "VA Office of Research and Development", "sponsor_class": "FED", "healthy_volunteers": false, "eligibility": { "minimum_age": "60 Years", "maximum_age": null, "sex": "ALL", "summary": "60 Years and older" }, "enrollment_count": 42, "start_date": "2005-10", "completion_date": "2009-09", "has_results": true, "last_update_posted_date": "2016-12-29", "last_synced_at": "2026-09-29T09:04:07.718Z", "location_count": 3, "location_summary": "Tuscaloosa, Alabama • Miami, Florida • Charleston, South Carolina", "locations": [ { "city": "Tuscaloosa", "state": "Alabama" }, { "city": "Miami", "state": "Florida" }, { "city": "Charleston", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00701675" }, { "nct_id": "NCT04476030", "title": "A Comparative Study of Sage-217 Plus an Antidepressant (ADT) Versus Placebo Plus an ADT in Adults With Major Depressive Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Depressive Disorder, Major" ], "interventions": [ { "name": "SAGE-217", "type": "DRUG" }, { "name": "Matching Placebo", "type": "DRUG" }, { "name": "Sertraline", "type": "DRUG" }, { "name": "Escitalopram", "type": "DRUG" }, { "name": "Citalopram", "type": "DRUG" }, { "name": "Duloxetine", "type": "DRUG" }, { "name": "Desvenlafaxine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Biogen", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "64 Years", "sex": "ALL", "summary": "18 Years to 64 Years" }, "enrollment_count": 440, "start_date": "2020-11-09", "completion_date": "2021-12-22", "has_results": true, "last_update_posted_date": "2023-12-22", "last_synced_at": "2026-09-29T09:04:07.718Z", "location_count": 51, "location_summary": "Dothan, Alabama • Phoenix, Arizona • Anaheim, California + 42 more", "locations": [ { "city": "Dothan", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Anaheim", "state": "California" }, { "city": "Costa Mesa", "state": "California" }, { "city": "Glendale", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04476030" }, { "nct_id": "NCT00086138", "title": "Depression in Alzheimer's Disease-2", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Alzheimer's Disease", "Depression" ], "interventions": [ { "name": "Sertraline (Zoloft)", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Johns Hopkins University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 131, "start_date": "2004-07", "completion_date": "2009-07", "has_results": true, "last_update_posted_date": "2017-04-11", "last_synced_at": "2026-09-29T09:04:07.718Z", "location_count": 5, "location_summary": "Los Angeles, California • Baltimore, Maryland • Rochester, New York + 2 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Baltimore", "state": "Maryland" }, { "city": "Rochester", "state": "New York" }, { "city": "Philadelphia", "state": "Pennsylvania" }, { "city": "North Charleston", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00086138" }, { "nct_id": "NCT01715805", "title": "Efficacy, Safety and Tolerability of Cariprazine as an Adjunctive Treatment to Antidepressant Therapy (ADT) in Patients With Major Depressive Disorder (MDD)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Major Depressive Disorder" ], "interventions": [ { "name": "Cariprazine", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Antidepressant Therapy (ADT)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Forest Laboratories", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 1022, "start_date": "2012-11-15", "completion_date": "2016-06-24", "has_results": true, "last_update_posted_date": "2019-08-28", "last_synced_at": "2026-09-29T09:04:07.718Z", "location_count": 83, "location_summary": "Tucson, Arizona • Little Rock, Arkansas • Cerritos, California + 68 more", "locations": [ { "city": "Tucson", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Cerritos", "state": "California" }, { "city": "Culver City", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01715805" }, { "nct_id": "NCT03033069", "title": "A Study of Flexible Dose Brexpiprazole as Monotherapy or Combination Therapy in the Treatment of Adults With Post-traumatic Stress Disorder (PTSD)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Stress Disorders, Post-Traumatic" ], "interventions": [ { "name": "Brexpiprazole", "type": "DRUG" }, { "name": "Sertraline", "type": "DRUG" }, { "name": "Brexpiprazole Matching Placebo", "type": "DRUG" }, { "name": "Sertraline Matching Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Otsuka Pharmaceutical Development & Commercialization, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 336, "start_date": "2017-01-26", "completion_date": "2018-11-12", "has_results": true, "last_update_posted_date": "2021-12-08", "last_synced_at": "2026-09-29T09:04:07.718Z", "location_count": 54, "location_summary": "Tuscaloosa, Alabama • Phoenix, Arizona • Little Rock, Arkansas + 48 more", "locations": [ { "city": "Tuscaloosa", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Rogers", "state": "Arkansas" }, { "city": "Bellflower", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03033069" }, { "nct_id": "NCT02504931", "title": "Serotonin Selective Reuptake Inhibitor Treatment of Dual Diagnosis Post-traumatic Stress Disorder and Alcohol Problems", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "PTSD", "Alcohol Use Disorder" ], "interventions": [ { "name": "Sertraline", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "The University of Texas Health Science Center at San Antonio", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "21 Years to 65 Years" }, "enrollment_count": 49, "start_date": "2011-04", "completion_date": "2016-12", "has_results": true, "last_update_posted_date": "2018-04-10", "last_synced_at": "2026-09-29T09:04:07.718Z", "location_count": 1, "location_summary": "San Antonio, Texas", "locations": [ { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02504931" }, { "nct_id": "NCT04174170", "title": "Brexpiprazole as Combination Therapy With Sertraline in the Treatment of Adults With Post-traumatic Stress Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Post Traumatic Stress Disorder" ], "interventions": [ { "name": "Brexpiprazole", "type": "DRUG" }, { "name": "Sertraline", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Otsuka Pharmaceutical Development & Commercialization, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 591, "start_date": "2019-10-30", "completion_date": "2023-08-15", "has_results": true, "last_update_posted_date": "2025-05-30", "last_synced_at": "2026-09-29T09:04:07.718Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT04174170" }, { "nct_id": "NCT04124614", "title": "Brexpiprazole as Combination Therapy With Sertraline in Treatment of Adults With PTSD", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Post Traumatic Stress Disorder" ], "interventions": [ { "name": "Brexpiprazole", "type": "DRUG" }, { "name": "Sertraline", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Otsuka Pharmaceutical Development & Commercialization, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 450, "start_date": "2019-10-17", "completion_date": "2023-08-08", "has_results": true, "last_update_posted_date": "2025-06-13", "last_synced_at": "2026-09-29T09:04:07.718Z", "location_count": 1, "location_summary": "San Diego, California", "locations": [ { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04124614" }, { "nct_id": "NCT01254305", "title": "Safety and Efficacy of Levomilnacipran ER (F2695 SR) in Adults With Fatigue Associated With Major Depressive Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Major Depressive Disorder" ], "interventions": [ { "name": "Levomilnacipran ER", "type": "DRUG" }, { "name": "Paroxetine, Sertraline, Citalopram or Fluoxetine.", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Forest Laboratories", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 262, "start_date": "2011-04", "completion_date": "2012-07", "has_results": true, "last_update_posted_date": "2014-08-06", "last_synced_at": "2026-09-29T09:04:07.718Z", "location_count": 20, "location_summary": "Birmingham, Alabama • Little Rock, Arkansas • Cerritos, California + 17 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Cerritos", "state": "California" }, { "city": "Fort Myers", "state": "Florida" }, { "city": "Jacksonville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT01254305" } ] }