{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sevelamer+HCl", "query": { "intervention": "Sevelamer HCl" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 12, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sevelamer+HCl&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-17T22:23:45.453Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00211939", "title": "CARE-2 (Calcium Acetate [PhosLo®]/Sevelamer[Renagel®] Evaluation Study 2) for Heart Calcification in Dialysis Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Calcinosis", "Arteriosclerosis", "Hyperparathyroidism, Secondary" ], "interventions": [ { "name": "calcium acetate", "type": "DRUG" }, { "name": "sevelamer", "type": "DRUG" }, { "name": "atorvastatin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Nabi Biopharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 203, "start_date": "2005-01", "completion_date": "2007-03", "has_results": false, "last_update_posted_date": "2008-01-08", "last_synced_at": "2026-09-17T22:23:45.453Z", "location_count": 1, "location_summary": "San Antonio, Texas", "locations": [ { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00211939" }, { "nct_id": "NCT00441545", "title": "Head to Head Study Against Sevelamer Hydrochloride", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chronic Kidney Disease, Stage 5" ], "interventions": [ { "name": "Fosrenol (Lanthanum Carbonate)", "type": "DRUG" }, { "name": "Sevelamer hydrochloride", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Shire", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 182, "start_date": "2007-01-05", "completion_date": "2008-07-31", "has_results": true, "last_update_posted_date": "2021-06-11", "last_synced_at": "2026-09-17T22:23:45.453Z", "location_count": 34, "location_summary": "Mesa, Arizona • Phoenix, Arizona • Tempe, Arizona + 29 more", "locations": [ { "city": "Mesa", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Tempe", "state": "Arizona" }, { "city": "Tempe", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT00441545" }, { "nct_id": "NCT00324376", "title": "Study to Compare Once A Day Sevelamer Dosing With Three Times Per Day Sevelamer Dosing", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Chronic Kidney Disease" ], "interventions": [ { "name": "Sevelamer hydrochloride", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Genzyme, a Sanofi Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 24, "start_date": "2003-03", "completion_date": "2004-05", "has_results": false, "last_update_posted_date": "2015-03-05", "last_synced_at": "2026-09-17T22:23:45.453Z", "location_count": 2, "location_summary": "Olympia Fields, Illinois • Cincinnati, Ohio", "locations": [ { "city": "Olympia Fields", "state": "Illinois" }, { "city": "Cincinnati", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT00324376" }, { "nct_id": "NCT00824460", "title": "Study of Phosphate Levels in Patients With Chronic Kidney Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Chronic Kidney Disease" ], "interventions": [ { "name": "1.25 g PA21 (250 mg iron)", "type": "DRUG" }, { "name": "5.0 g PA21 (1,000 mg iron)", "type": "DRUG" }, { "name": "7.5 g PA21 (1,500 mg iron)", "type": "DRUG" }, { "name": "10.0 g PA21 (2,000 mg iron)", "type": "DRUG" }, { "name": "12.5 g PA21 (2,500 mg iron)", "type": "DRUG" }, { "name": "Sevelamer hydrochloride", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Vifor Pharma", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 154, "start_date": "2008-12", "completion_date": "2010-03", "has_results": true, "last_update_posted_date": "2014-04-01", "last_synced_at": "2026-09-17T22:23:45.453Z", "location_count": 9, "location_summary": "Arvada, Colorado • Denver, Colorado • Pembroke Pines, Florida + 6 more", "locations": [ { "city": "Arvada", "state": "Colorado" }, { "city": "Denver", "state": "Colorado" }, { "city": "Pembroke Pines", "state": "Florida" }, { "city": "Kansas City", "state": "Kansas" }, { "city": "Fresh Meadows", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00824460" }, { "nct_id": "NCT04278404", "title": "Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Coronavirus Infection (COVID-19)", "Pulmonary Arterial Hypertension", "Urinary Tract Infections in Children", "Hypertension", "Pain", "Hyperphosphatemia", "Primary Hyperaldosteronism", "Edema", "Hypokalemia", "Heart Failure", "Hemophilia", "Menorrhagia", "Insomnia", "Pneumonia", "Skin Infection", "Arrythmia", "Asthma in Children", "Bronchopulmonary Dysplasia", "Adrenal Insufficiency", "Fibrinolysis; Hemorrhage", "Attention Deficit Hyperactivity Disorder", "Multisystem Inflammatory Syndrome in Children (MIS-C)", "Kawasaki Disease", "Coagulation Disorder", "Down Syndrome" ], "interventions": [ { "name": "The POP02 study is collecting bodily fluid samples (i.e., whole blood, effluent samples) of children prescribed the following drugs of interest per standard of care:", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "0 Years", "maximum_age": "20 Years", "sex": "ALL", "summary": "0 Years to 20 Years" }, "enrollment_count": 5000, "start_date": "2020-03-05", "completion_date": "2026-12", "has_results": false, "last_update_posted_date": "2026-08-21", "last_synced_at": "2026-09-17T22:23:45.453Z", "location_count": 49, "location_summary": "Phoenix, Arizona • Little Rock, Arkansas • Los Angeles, California + 40 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Los Angeles", "state": "California" }, { "city": "Palo Alto", "state": "California" }, { "city": "Aurora", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT04278404" }, { "nct_id": "NCT00704483", "title": "Efficacy of SBR759 in Lowering Serum Phosphate Levels in Chronic Kidney Disease Patients on Hemodialysis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Hyperphosphatemia Patients With Chronic Kidney Disease on 3x/Week Replacement Therapy" ], "interventions": [ { "name": "SBR759", "type": "DRUG" }, { "name": "Sevelamer HCl", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novartis Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 321, "start_date": "2008-07", "completion_date": null, "has_results": false, "last_update_posted_date": "2020-12-19", "last_synced_at": "2026-09-17T22:23:45.453Z", "location_count": 19, "location_summary": "Chula Vista, California • La Mesa, California • Whittier, California + 16 more", "locations": [ { "city": "Chula Vista", "state": "California" }, { "city": "La Mesa", "state": "California" }, { "city": "Whittier", "state": "California" }, { "city": "Denver", "state": "Colorado" }, { "city": "North Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT00704483" }, { "nct_id": "NCT00440648", "title": "Cross-Over Study of Sevelamer Hydrochloride and Sevelamer Carbonate", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Chronic Kidney Disease" ], "interventions": [ { "name": "sevelamer carbonate, sevelamer hydrochloride", "type": "DRUG" }, { "name": "sevelamer hydrochloride, sevelamer carbonate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Genzyme, a Sanofi Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 80, "start_date": "2005-03", "completion_date": "2006-07", "has_results": false, "last_update_posted_date": "2014-03-19", "last_synced_at": "2026-09-17T22:23:45.453Z", "location_count": 15, "location_summary": "Mobile, Alabama • Riverside, California • Greenwood Village, Colorado + 11 more", "locations": [ { "city": "Mobile", "state": "Alabama" }, { "city": "Riverside", "state": "California" }, { "city": "Greenwood Village", "state": "Colorado" }, { "city": "Berwyn", "state": "Illinois" }, { "city": "Crestwood", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT00440648" }, { "nct_id": "NCT01431326", "title": "Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Adenovirus", "Anesthesia", "Anxiety", "Anxiolysis", "Autism", "Autistic Disorder", "Bacterial Meningitis", "Bacterial Septicemia", "Benzodiazepine", "Bipolar Disorder", "Bone and Joint Infections", "Central Nervous System Infections", "Convulsions", "Cytomegalovirus Retinitis", "Early-onset Schizophrenia Spectrum Disorders", "Epilepsy", "General Anesthesia", "Gynecologic Infections", "Herpes Simplex Virus", "Infantile Hemangioma", "Infection", "Inflammation", "Inflammatory Conditions", "Intra-abdominal Infections", "Lower Respiratory Tract Infections", "Migraines", "Pain", "Pneumonia", "Schizophrenia", "Sedation", "Seizures", "Skeletal Muscle Spasms", "Skin and Skin-structure Infections", "Treatment-resistant Schizophrenia", "Urinary Tract Infections", "Withdrawal", "Sepsis", "Gram-negative Infection", "Bradycardia", "Cardiac Arrest", "Cardiac Arrhythmia", "Staphylococcal Infections", "Nosocomial Pneumonia", "Neuromuscular Blockade", "Methicillin Resistant Staphylococcus Aureus", "Endocarditis", "Neutropenia", "Headache", "Fibrinolytic Bleeding", "Pulmonary Arterial Hypertension", "CMV Retinitis", "Hypertension", "Chronic Kidney Diseases", "Hyperaldosteronism", "Hypokalemia", "Heart Failure", "Hemophilia", "Heavy Menstrual Bleeding", "Insomnia" ], "interventions": [ { "name": "The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care:", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Daniel Benjamin", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "21 Years", "sex": "ALL", "summary": "Up to 21 Years" }, "enrollment_count": 3520, "start_date": "2011-11", "completion_date": "2019-11", "has_results": false, "last_update_posted_date": "2023-09-06", "last_synced_at": "2026-09-17T22:23:45.453Z", "location_count": 43, "location_summary": "Anchorage, Alaska • Little Rock, Arkansas • La Jolla, California + 37 more", "locations": [ { "city": "Anchorage", "state": "Alaska" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "La Jolla", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01431326" }, { "nct_id": "NCT00844662", "title": "Phase III Study to Investigate the Safety and Efficacy of Fermagate and Sevelamer Hydrochloride", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chronic Kidney Failure" ], "interventions": [ { "name": "Fermagate", "type": "DRUG" }, { "name": "Sevelamer hydrochloride", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Ineos Healthcare Limited", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1000, "start_date": "2009-07", "completion_date": "2011-10", "has_results": false, "last_update_posted_date": "2010-10-19", "last_synced_at": "2026-09-17T22:23:45.453Z", "location_count": 40, "location_summary": "Hot Springs, Arkansas • Bakersfield, California • Lynwood, California + 32 more", "locations": [ { "city": "Hot Springs", "state": "Arkansas" }, { "city": "Bakersfield", "state": "California" }, { "city": "Lynwood", "state": "California" }, { "city": "Monterey Park", "state": "California" }, { "city": "Pasadena", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00844662" }, { "nct_id": "NCT00324571", "title": "Dialysis Clinical Outcomes Revisited (DCOR) Trial", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Chronic Kidney Disease" ], "interventions": [ { "name": "Sevelamer hydrochloride", "type": "DRUG" }, { "name": "Calcium-based phosphate binder", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Genzyme, a Sanofi Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 2000, "start_date": "2001-03", "completion_date": "2006-02", "has_results": false, "last_update_posted_date": "2015-03-18", "last_synced_at": "2026-09-17T22:23:45.453Z", "location_count": 72, "location_summary": "Gadsden, Alabama • Huntsville, Alabama • Tucson, Arizona + 63 more", "locations": [ { "city": "Gadsden", "state": "Alabama" }, { "city": "Huntsville", "state": "Alabama" }, { "city": "Tucson", "state": "Arizona" }, { "city": "El Cerrito", "state": "California" }, { "city": "Escondido", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00324571" } ] }