{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Severe+Sepsis+Prediction",
    "query": {
      "intervention": "Severe Sepsis Prediction"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 6,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-22T09:09:37.508Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03235193",
      "title": "Predictive algoRithm for EValuation and Intervention in SEpsis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sepsis",
        "Septic Shock",
        "Severe Sepsis"
      ],
      "interventions": [
        {
          "name": "Severe Sepsis Prediction",
          "type": "OTHER"
        },
        {
          "name": "Severe Sepsis Detection",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Dascena",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2296,
      "start_date": "2017-07-01",
      "completion_date": "2017-08-30",
      "has_results": false,
      "last_update_posted_date": "2021-09-21",
      "last_synced_at": "2026-09-22T09:09:37.508Z",
      "location_count": 1,
      "location_summary": "Huntington, West Virginia",
      "locations": [
        {
          "city": "Huntington",
          "state": "West Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03235193"
    },
    {
      "nct_id": "NCT02972827",
      "title": "Monitoring Devices in Prediction of Fluid Responsiveness in Severe Sepsis and Septic Shock",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Severe Sepsis",
        "Septic Shock"
      ],
      "interventions": [
        {
          "name": "NICOM/FloTrac",
          "type": "DEVICE"
        },
        {
          "name": "Crystalloid Fluid Challenge",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Santa Barbara Cottage Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 38,
      "start_date": "2015-05",
      "completion_date": "2022-05",
      "has_results": false,
      "last_update_posted_date": "2021-07-02",
      "last_synced_at": "2026-09-22T09:09:37.508Z",
      "location_count": 1,
      "location_summary": "Santa Barbara, California",
      "locations": [
        {
          "city": "Santa Barbara",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02972827"
    },
    {
      "nct_id": "NCT03015454",
      "title": "An Algorithm Driven Sepsis Prediction Biomarker",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sepsis",
        "Septic Shock",
        "Severe Sepsis"
      ],
      "interventions": [
        {
          "name": "Severe Sepsis Prediction",
          "type": "OTHER"
        },
        {
          "name": "Severe Sepsis Detection",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Dascena",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 142,
      "start_date": "2016-12",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2021-09-23",
      "last_synced_at": "2026-09-22T09:09:37.508Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03015454"
    },
    {
      "nct_id": "NCT01392508",
      "title": "IMproved PREdiction of Severe Sepsis in the Emergency Department",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Systemic Inflammatory Response Syndrome (SIRS)",
        "Sepsis",
        "Severe Sepsis",
        "Septic Shock"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Axis Shield Diagnostics Ltd",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 759,
      "start_date": "2011-03",
      "completion_date": "2015-09",
      "has_results": false,
      "last_update_posted_date": "2017-04-14",
      "last_synced_at": "2026-09-22T09:09:37.508Z",
      "location_count": 1,
      "location_summary": "Camden, New Jersey",
      "locations": [
        {
          "city": "Camden",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01392508"
    },
    {
      "nct_id": "NCT03113721",
      "title": "Assessment of Heparin Binding Protein for the Prediction of Severe Sepsis",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Sepsis",
        "Septic Shock",
        "Sepsis With Acute Organ Dysfunction"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Axis Shield Diagnostics Ltd",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 571,
      "start_date": "2017-03-27",
      "completion_date": "2019-03-01",
      "has_results": false,
      "last_update_posted_date": "2019-01-09",
      "last_synced_at": "2026-09-22T09:09:37.508Z",
      "location_count": 5,
      "location_summary": "Philadelphia, Pennsylvania • York, Pennsylvania • Nashville, Tennessee + 1 more",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "York",
          "state": "Pennsylvania"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03113721"
    },
    {
      "nct_id": "NCT07223684",
      "title": "TDAP in Burn Patients (Group 2)",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Sepsis",
        "Burn Injury",
        "Wound Healing",
        "Critical Illness",
        "Multiple Organ Dysfunction Syndrome"
      ],
      "interventions": [
        {
          "name": "Observational Cohort (No Intervention)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Henry M. Jackson Foundation for the Advancement of Military Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 80,
      "start_date": "2026-05-15",
      "completion_date": "2027-12-15",
      "has_results": false,
      "last_update_posted_date": "2026-02-04",
      "last_synced_at": "2026-09-22T09:09:37.508Z",
      "location_count": 3,
      "location_summary": "Tampa, Florida • Atlanta, Georgia • Houston, Texas",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07223684"
    }
  ]
}