{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sham%2FNo+Intervention&page=2",
    "query": {
      "intervention": "Sham/No Intervention",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sham%2FNo+Intervention&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-26T09:07:36.149Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04961112",
      "title": "Evaluating the Efficacy of Cranial Electrotherapy Stimulation in Mitigating Anxiety-induced Cognitive Deficits",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anxiety",
        "Cognitive Deficit"
      ],
      "interventions": [
        {
          "name": "Cranial Electrotherapy Stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Sham Cranial Electrotherapy Stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Tufts University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "28 Years",
        "sex": "ALL",
        "summary": "18 Years to 28 Years"
      },
      "enrollment_count": 124,
      "start_date": "2021-09-06",
      "completion_date": "2025-04-07",
      "has_results": false,
      "last_update_posted_date": "2025-04-10",
      "last_synced_at": "2026-09-26T09:07:36.149Z",
      "location_count": 1,
      "location_summary": "Medford, Massachusetts",
      "locations": [
        {
          "city": "Medford",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04961112"
    },
    {
      "nct_id": "NCT07197502",
      "title": "Treatment of Borderline Personality Disorder With rTMS",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Borderline Personality Disorder",
        "Borderline Personality",
        "BPD - Borderline Personality Disorder"
      ],
      "interventions": [
        {
          "name": "Transcranial Magnetic Stimulation (TMS)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 30,
      "start_date": "2025-03-01",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-08-10",
      "last_synced_at": "2026-09-26T09:07:36.149Z",
      "location_count": 2,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07197502"
    },
    {
      "nct_id": "NCT04230577",
      "title": "Photobiomodulation to Improve Cognition in TBI, With fMRI",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Traumatic Brain Injury",
        "Closed Head Injury",
        "Cognitive Dysfunction"
      ],
      "interventions": [
        {
          "name": "Real LED Intervention",
          "type": "DEVICE"
        },
        {
          "name": "Sham LED Intervention",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Boston VA Research Institute, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 20,
      "start_date": "2019-08-07",
      "completion_date": "2023-09-30",
      "has_results": false,
      "last_update_posted_date": "2022-02-25",
      "last_synced_at": "2026-09-26T09:07:36.149Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04230577"
    },
    {
      "nct_id": "NCT03629275",
      "title": "Investigation of Neural Stem Cells in Ischemic Stroke",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Ischemic Stroke",
        "Chronic Stroke",
        "Hemiparesis",
        "Arm Paralysis"
      ],
      "interventions": [
        {
          "name": "CTX0E03 Drug Product and delivery device",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT",
        "DRUG"
      ],
      "sponsor": "ReNeuron Limited",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "35 Years to 75 Years"
      },
      "enrollment_count": 15,
      "start_date": "2018-08-31",
      "completion_date": "2021-03-02",
      "has_results": false,
      "last_update_posted_date": "2021-08-13",
      "last_synced_at": "2026-09-26T09:07:36.149Z",
      "location_count": 23,
      "location_summary": "Little Rock, Arkansas • Irvine, California • Los Angeles, California + 19 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Irvine",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03629275"
    },
    {
      "nct_id": "NCT05906602",
      "title": "Motor and Neurophysiological Changes After Ischemic Conditioning in Individuals With Stroke",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stroke"
      ],
      "interventions": [
        {
          "name": "Real Ischemic Conditioning",
          "type": "DEVICE"
        },
        {
          "name": "Sham Ischemic Conditioning",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Illinois at Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2024-05-20",
      "completion_date": "2025-12-31",
      "has_results": true,
      "last_update_posted_date": "2026-05-19",
      "last_synced_at": "2026-09-26T09:07:36.149Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05906602"
    },
    {
      "nct_id": "NCT01582958",
      "title": "The Effect of OMT on Patients With COPD: Correlating Pulmonary Function Tests With Biochemical Alterations",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Obstructive Pulmonary Disease"
      ],
      "interventions": [
        {
          "name": "Osteopathic Manipulative Treatment (OMT)",
          "type": "PROCEDURE"
        },
        {
          "name": "sham omt",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "Michigan State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "49 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "49 Years to 80 Years"
      },
      "enrollment_count": 45,
      "start_date": "2013-04",
      "completion_date": "2015-08",
      "has_results": false,
      "last_update_posted_date": "2015-10-08",
      "last_synced_at": "2026-09-26T09:07:36.149Z",
      "location_count": 1,
      "location_summary": "Lansing, Michigan",
      "locations": [
        {
          "city": "Lansing",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01582958"
    },
    {
      "nct_id": "NCT06871124",
      "title": "Early Neuromodulation in Traumatic Brain Injury",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Traumatic Brain Injury (TBI) Patients"
      ],
      "interventions": [
        {
          "name": "transcranial electrical stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Sham Comparator",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 60,
      "start_date": "2025-06-16",
      "completion_date": "2028-04-30",
      "has_results": false,
      "last_update_posted_date": "2026-06-03",
      "last_synced_at": "2026-09-26T09:07:36.149Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06871124"
    },
    {
      "nct_id": "NCT03222752",
      "title": "Efficacy of Cranial Electrotherapy Stimulation (CES) for the Treatment of Major Depressive Disorder",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Major Depressive Disorder"
      ],
      "interventions": [
        {
          "name": "Cranial Electrotherapy Stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Sham Cranial Electrotherapy Stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Electromedical Products International, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "22 Years to 65 Years"
      },
      "enrollment_count": 5,
      "start_date": "2017-06-05",
      "completion_date": "2023-04-25",
      "has_results": false,
      "last_update_posted_date": "2023-04-27",
      "last_synced_at": "2026-09-26T09:07:36.149Z",
      "location_count": 1,
      "location_summary": "Forest, Virginia",
      "locations": [
        {
          "city": "Forest",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03222752"
    },
    {
      "nct_id": "NCT06634771",
      "title": "Flexibility, Alcohol Misuse, and Excitation",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Behavioral Flexibility",
        "Healthy Volunteers",
        "High Risk Alcohol Use"
      ],
      "interventions": [
        {
          "name": "10 Hz transcranial alternating current stimulation (tACS)",
          "type": "OTHER"
        },
        {
          "name": "sham transcranial alternating current stimulation (tACS)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "22 Years to 50 Years"
      },
      "enrollment_count": 7,
      "start_date": "2024-07-18",
      "completion_date": "2025-01-24",
      "has_results": true,
      "last_update_posted_date": "2026-03-27",
      "last_synced_at": "2026-09-26T09:07:36.149Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06634771"
    },
    {
      "nct_id": "NCT06134856",
      "title": "A Study Examining Changes in Pain After Manual Therapy in People With Achilles Tendon Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Achilles Tendinopathy",
        "Ankle Strain",
        "Achilles Tendon Pain",
        "Achilles Tendonitis"
      ],
      "interventions": [
        {
          "name": "Ankle mobilization",
          "type": "PROCEDURE"
        },
        {
          "name": "Sham treatment",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Philadelphia College of Osteopathic Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 38,
      "start_date": "2023-12-05",
      "completion_date": "2025-03-05",
      "has_results": false,
      "last_update_posted_date": "2025-03-28",
      "last_synced_at": "2026-09-26T09:07:36.149Z",
      "location_count": 1,
      "location_summary": "Suwanee, Georgia",
      "locations": [
        {
          "city": "Suwanee",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06134856"
    }
  ]
}