{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sham+%28Control%29&page=36", "query": { "intervention": "Sham (Control)", "page": 36 }, "page_size": 10 }, "pagination": { "page": 36, "page_size": 10, "total_count": 1661, "total_pages": 167, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sham+%28Control%29&page=37&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sham+%28Control%29&page=35&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-31T09:40:31.811Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04408352", "title": "RF Ablation of the Trigone for the Treatment of UUI", "overall_status": "SUSPENDED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Urgent Urinary Incontinence" ], "interventions": [ { "name": "selective bladder denervation using RF energy", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Hologic, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 225, "start_date": "2020-04-27", "completion_date": "2030-05", "has_results": false, "last_update_posted_date": "2024-02-28", "last_synced_at": "2026-10-31T09:40:31.811Z", "location_count": 6, "location_summary": "Wichita, Kansas • Shreveport, Louisiana • Pittsburgh, Pennsylvania + 2 more", "locations": [ { "city": "Wichita", "state": "Kansas" }, { "city": "Shreveport", "state": "Louisiana" }, { "city": "Pittsburgh", "state": "Pennsylvania" }, { "city": "Pittsburgh", "state": "Pennsylvania" }, { "city": "Franklin", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT04408352" }, { "nct_id": "NCT07470229", "title": "Transcutaneous Vagus Nerve Stimulation (tVNS) and Stress Regulation During Performance Tasks", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Stress Response" ], "interventions": [ { "name": "Transcutaneous Vagus Nerve Stimulation (tVNS)", "type": "DEVICE" }, { "name": "Evaluative Stress Task", "type": "BEHAVIORAL" } ], "intervention_types": [ "DEVICE", "BEHAVIORAL" ], "sponsor": "University of Florida", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 200, "start_date": "2026-03-15", "completion_date": "2026-04-15", "has_results": false, "last_update_posted_date": "2026-03-13", "last_synced_at": "2026-10-31T09:40:31.811Z", "location_count": 1, "location_summary": "Gainesville, Florida", "locations": [ { "city": "Gainesville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT07470229" }, { "nct_id": "NCT06131502", "title": "Sonication-based OCD Neurosurgical Intervention Via Capsulotomy", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Obsessive-Compulsive Disorder" ], "interventions": [ { "name": "ExAblate MR-guided Focused Ultrasound Bilateral Anterior Capsulotomy", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Brigham and Women's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "25 Years", "maximum_age": "64 Years", "sex": "ALL", "summary": "25 Years to 64 Years" }, "enrollment_count": 66, "start_date": "2026-08", "completion_date": "2032-08", "has_results": false, "last_update_posted_date": "2026-02-25", "last_synced_at": "2026-10-31T09:40:31.811Z", "location_count": 2, "location_summary": "Palo Alto, California • Boston, Massachusetts", "locations": [ { "city": "Palo Alto", "state": "California" }, { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT06131502" }, { "nct_id": "NCT04967170", "title": "A Study to Evaluate Platelet Rich Plasma to Treat Vulvar Lichen Sclerosus", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Vulvar Lichen Sclerosus" ], "interventions": [ { "name": "Autologous Platelet-Rich Plasma (PRP)", "type": "BIOLOGICAL" }, { "name": "Sham Procedure", "type": "OTHER" } ], "intervention_types": [ "BIOLOGICAL", "OTHER" ], "sponsor": "Jennifer R. Arthurs", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 30, "start_date": "2022-01-19", "completion_date": "2025-12-12", "has_results": false, "last_update_posted_date": "2026-07-22", "last_synced_at": "2026-10-31T09:40:31.811Z", "location_count": 1, "location_summary": "Jacksonville, Florida", "locations": [ { "city": "Jacksonville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT04967170" }, { "nct_id": "NCT05637801", "title": "A Pivotal Study of Sensory Stimulation in Alzheimer's Disease (HOPE Study)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Alzheimer Disease", "Alzheimer Disease 1", "Alzheimer Disease 2", "Alzheimer Disease 3", "Alzheimer Disease, Early Onset", "Alzheimer Disease, Late Onset", "Alzheimer Disease 9", "Alzheimer Disease 4", "Alzheimer Disease 7", "Alzheimer Disease 17", "Alzheimer's Dementia Late Onset", "Alzheimer Disease 5", "Alzheimer Disease 6", "Alzheimer Disease 8", "Alzheimer Disease 10", "Alzheimer Disease 11", "Alzheimer Disease 12", "Alzheimer Disease 13", "Alzheimer Disease 14", "Alzheimer Disease 15", "Alzheimer Disease 16", "Alzheimer Disease 18", "Alzheimer Disease 19", "Dementia", "Dementia Alzheimers", "Dementia, Mild", "Dementia of Alzheimer Type", "Dementia Moderate", "Dementia Senile", "Mild Cognitive Impairment", "Mild Dementia", "MCI", "Cognitive Impairment", "Cognitive Decline", "Cognitive Impairment, Mild" ], "interventions": [ { "name": "Spectris™ AD - Active", "type": "DEVICE" }, { "name": "Spectris™ AD - Sham", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Cognito Therapeutics, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "50 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "50 Years to 90 Years" }, "enrollment_count": 673, "start_date": "2022-12-13", "completion_date": "2026-08-17", "has_results": false, "last_update_posted_date": "2026-09-09", "last_synced_at": "2026-10-31T09:40:31.811Z", "location_count": 68, "location_summary": "Gilbert, Arizona • Phoenix, Arizona • Sun City, Arizona + 62 more", "locations": [ { "city": "Gilbert", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Sun City", "state": "Arizona" }, { "city": "Anaheim", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05637801" }, { "nct_id": "NCT06362187", "title": "VR Pilot for Pancreatitis", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Chronic Pancreatitis", "Recurrent Pancreatitis" ], "interventions": [ { "name": "Gut Directed VR", "type": "DEVICE" }, { "name": "Sham Control VR", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Cedars-Sinai Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 20, "start_date": "2027-07-22", "completion_date": "2029-05", "has_results": false, "last_update_posted_date": "2026-08-05", "last_synced_at": "2026-10-31T09:40:31.811Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06362187" }, { "nct_id": "NCT04196933", "title": "Analysis of Vestibular Compensation Following Clinical Intervention for Vestibular Schwannoma", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Migraine", "Vestibular Migraine", "Vestibular Schwannoma", "Motion Sickness", "Dizziness", "Vestibular Disorder" ], "interventions": [ { "name": "Temporal Binding Adaptation - PSS training", "type": "BEHAVIORAL" }, { "name": "Temporal Binding Adaptation - PSS adaptation with VI stimulation", "type": "BEHAVIORAL" }, { "name": "Chronic Motion-modulated Stimulation", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Massachusetts Eye and Ear Infirmary", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "8 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "8 Years to 80 Years" }, "enrollment_count": 0, "start_date": "2019-09-05", "completion_date": "2025-12-31", "has_results": false, "last_update_posted_date": "2025-04-16", "last_synced_at": "2026-10-31T09:40:31.811Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT04196933" }, { "nct_id": "NCT03416049", "title": "The Effects of Pulsed Elelectro-Magnetic Fields (\"PEMF\") in the Treatment of Venous Stasis Leg Ulcers", "overall_status": "TERMINATED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Venous Stasis Ulcers" ], "interventions": [ { "name": "PEMF therapy with a high-power PEMF device", "type": "DEVICE" }, { "name": "PEMF therapy with a medium PEMF power device", "type": "DEVICE" }, { "name": "PEMF therapy with a low-power PEMF device", "type": "DEVICE" }, { "name": "PEMF therapy with the sham PEMF device", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "PEMF Systems, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 33, "start_date": "2018-11-08", "completion_date": "2023-01-20", "has_results": false, "last_update_posted_date": "2024-04-05", "last_synced_at": "2026-10-31T09:40:31.811Z", "location_count": 1, "location_summary": "Detroit, Michigan", "locations": [ { "city": "Detroit", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT03416049" }, { "nct_id": "NCT04341948", "title": "Treatment of Post-Operative Pain Following Orthopedic Surgery With SPRINT® Peripheral Nerve Stimulation (PNS) System", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Postoperative Pain", "Total Knee Replacement", "Total Knee Arthroplasty", "Partial Knee Replacement" ], "interventions": [ { "name": "SPRINT Peripheral Nerve Stimulation (PNS) System", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "SPR Therapeutics, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 56, "start_date": "2020-08-06", "completion_date": "2024-06-27", "has_results": true, "last_update_posted_date": "2025-08-27", "last_synced_at": "2026-10-31T09:40:31.811Z", "location_count": 10, "location_summary": "Little Rock, Arkansas • San Diego, California • Gainesville, Florida + 7 more", "locations": [ { "city": "Little Rock", "state": "Arkansas" }, { "city": "San Diego", "state": "California" }, { "city": "Gainesville", "state": "Florida" }, { "city": "Newnan", "state": "Georgia" }, { "city": "Evanston", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT04341948" }, { "nct_id": "NCT03185143", "title": "Low-Dose Naltrexone and Acetaminophen Combination and Sumatriptan in the Acute Treatment of Migraine With Nausea", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Migraine With and Without Aura" ], "interventions": [ { "name": "Naltrexone and Acetaminophen Combination", "type": "DRUG" }, { "name": "Sumatriptan 100 mg", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Allodynic Therapeutics, Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 36, "start_date": "2017-06-27", "completion_date": "2018-05-07", "has_results": false, "last_update_posted_date": "2021-04-14", "last_synced_at": "2026-10-31T09:40:31.811Z", "location_count": 1, "location_summary": "North Miami, Florida", "locations": [ { "city": "North Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT03185143" } ] }