{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sham+%28Control%29&page=48",
    "query": {
      "intervention": "Sham (Control)",
      "page": 48
    },
    "page_size": 10
  },
  "pagination": {
    "page": 48,
    "page_size": 10,
    "total_count": 1662,
    "total_pages": 167,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sham+%28Control%29&page=49&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sham+%28Control%29&page=47&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-02T14:52:13.100Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01748942",
      "title": "Dexamethasone in Reducing Oral Pain and Dry Mouth After Surgery in Patients With Oropharyngeal Cancer",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dysphagia",
        "Pain",
        "Stage I Oropharyngeal Squamous Cell Carcinoma",
        "Stage II Oropharyngeal Squamous Cell Carcinoma",
        "Stage III Oropharyngeal Squamous Cell Carcinoma"
      ],
      "interventions": [
        {
          "name": "Dexamethasone",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        },
        {
          "name": "Quality-of-Life Assessment",
          "type": "PROCEDURE"
        },
        {
          "name": "Questionnaire Administration",
          "type": "OTHER"
        },
        {
          "name": "Transoral Robotic Surgery",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "OHSU Knight Cancer Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 76,
      "start_date": "2012-12",
      "completion_date": "2017-03-29",
      "has_results": true,
      "last_update_posted_date": "2018-06-19",
      "last_synced_at": "2026-11-02T14:52:13.100Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01748942"
    },
    {
      "nct_id": "NCT04191031",
      "title": "Study to Evaluate Iovera®° in Adult Patients Undergoing Total Knee Arthroplasty",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Post-Operative Pain Management"
      ],
      "interventions": [
        {
          "name": "ioveraº",
          "type": "DEVICE"
        },
        {
          "name": "ioveraº sham",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Pacira Pharmaceuticals, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 79,
      "start_date": "2020-09-30",
      "completion_date": "2022-07-12",
      "has_results": false,
      "last_update_posted_date": "2023-01-25",
      "last_synced_at": "2026-11-02T14:52:13.100Z",
      "location_count": 7,
      "location_summary": "Fremont, California • Pasadena, California • Tamarac, Florida + 4 more",
      "locations": [
        {
          "city": "Fremont",
          "state": "California"
        },
        {
          "city": "Pasadena",
          "state": "California"
        },
        {
          "city": "Tamarac",
          "state": "Florida"
        },
        {
          "city": "Towson",
          "state": "Maryland"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04191031"
    },
    {
      "nct_id": "NCT03183037",
      "title": "Acupuncture for Symptoms of Nerve Damage",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Peripheral Neuropathy",
        "Chemotherapy-induced Peripheral Neuropathy"
      ],
      "interventions": [
        {
          "name": "Acupuncture",
          "type": "PROCEDURE"
        },
        {
          "name": "Sham Acupuncture",
          "type": "PROCEDURE"
        },
        {
          "name": "Usual Care Group",
          "type": "OTHER"
        },
        {
          "name": "questionnaires",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "Memorial Sloan Kettering Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 75,
      "start_date": "2017-06-07",
      "completion_date": "2024-05-02",
      "has_results": false,
      "last_update_posted_date": "2024-05-03",
      "last_synced_at": "2026-11-02T14:52:13.100Z",
      "location_count": 2,
      "location_summary": "Commack, New York • New York, New York",
      "locations": [
        {
          "city": "Commack",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03183037"
    },
    {
      "nct_id": "NCT04857996",
      "title": "Safety, Tolerability and Evidence of Activity Study of UBX1325 in Patients With Diabetic Macular Edema (BEHOLD)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Diabetic Macular Edema (DME)"
      ],
      "interventions": [
        {
          "name": "UBX1325",
          "type": "DRUG"
        },
        {
          "name": "Sham",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Unity Biotechnology, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 65,
      "start_date": "2021-06-25",
      "completion_date": "2023-04-06",
      "has_results": true,
      "last_update_posted_date": "2024-05-16",
      "last_synced_at": "2026-11-02T14:52:13.100Z",
      "location_count": 19,
      "location_summary": "Phoenix, Arizona • Bakersfield, California • Encino, California + 15 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Bakersfield",
          "state": "California"
        },
        {
          "city": "Encino",
          "state": "California"
        },
        {
          "city": "Huntington Beach",
          "state": "California"
        },
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04857996"
    },
    {
      "nct_id": "NCT07634146",
      "title": "Evaluation of the Migraceutics® Phase-Specific Dietary Supplement Regimen on Quality of Life, Work Productivity, and Biomarkers in Adult Migraineurs: The Migraceutics® START Study",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Migraine",
        "Migraine Disease",
        "Migraine Disorder",
        "Migraine Headache",
        "Migraine Disability",
        "Migraine in Adults",
        "Menstrual Migraine",
        "Menstrual Migraine (MM) Headaches"
      ],
      "interventions": [
        {
          "name": "Foundational dietary supplement",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Luteal phase dietary supplement add-on",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Migraine phase dietary supplement add-on",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Reference dietary supplement",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Miracle Wellness LLC",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 920,
      "start_date": "2026-07-08",
      "completion_date": "2028-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-06-08",
      "last_synced_at": "2026-11-02T14:52:13.100Z",
      "location_count": 1,
      "location_summary": "Lutherville-Timonium, Maryland",
      "locations": [
        {
          "city": "Lutherville-Timonium",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07634146"
    },
    {
      "nct_id": "NCT04606095",
      "title": "Explosive Synchronization of Brain Network Activity in Chronic Pain",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fibromyalgia",
        "Healthy Volunteers"
      ],
      "interventions": [
        {
          "name": "EEG",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Neuroimaging EEG/fMRI (Aim 1)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "HD-tDCS treatments",
          "type": "DEVICE"
        },
        {
          "name": "Sham HD-tDCS treatments",
          "type": "DEVICE"
        },
        {
          "name": "Neuroimaging EEG/fMRI (Aim 3)",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "DEVICE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "74 Years",
        "sex": "ALL",
        "summary": "19 Years to 74 Years"
      },
      "enrollment_count": 150,
      "start_date": "2020-11-13",
      "completion_date": "2026-12-20",
      "has_results": false,
      "last_update_posted_date": "2026-09-30",
      "last_synced_at": "2026-11-02T14:52:13.100Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04606095"
    },
    {
      "nct_id": "NCT01404039",
      "title": "Investigating Motor Cortex Processing for Pain Modulation",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Motor Activity"
      ],
      "interventions": [
        {
          "name": "Motor Learning",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Somatosensory Learning",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Observational Task",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Mental Imagery",
          "type": "BEHAVIORAL"
        },
        {
          "name": "transcranial direct current stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DEVICE"
      ],
      "sponsor": "Spaulding Rehabilitation Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "MALE",
        "summary": "18 Years to 64 Years · Male only"
      },
      "enrollment_count": 115,
      "start_date": "2010-09",
      "completion_date": "2014-04",
      "has_results": true,
      "last_update_posted_date": "2020-04-24",
      "last_synced_at": "2026-11-02T14:52:13.100Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01404039"
    },
    {
      "nct_id": "NCT03046030",
      "title": "Mechanistic Studies on Video-guided Acupuncture Imagery Treatment of Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain"
      ],
      "interventions": [
        {
          "name": "Real acupuncture",
          "type": "OTHER"
        },
        {
          "name": "Sham acupuncture",
          "type": "OTHER"
        },
        {
          "name": "VGAIT",
          "type": "OTHER"
        },
        {
          "name": "VGAIT control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 27,
      "start_date": "2017-01",
      "completion_date": "2017-08-28",
      "has_results": false,
      "last_update_posted_date": "2026-07-21",
      "last_synced_at": "2026-11-02T14:52:13.100Z",
      "location_count": 1,
      "location_summary": "Charlestown, Massachusetts",
      "locations": [
        {
          "city": "Charlestown",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03046030"
    },
    {
      "nct_id": "NCT04946760",
      "title": "Effects of OMT on Gait Kinematics and Postural Control in Parkinson Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Parkinson Disease"
      ],
      "interventions": [
        {
          "name": "Sham Manipulation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of North Texas Health Science Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 113,
      "start_date": "2016-09-01",
      "completion_date": "2019-09-16",
      "has_results": false,
      "last_update_posted_date": "2021-07-01",
      "last_synced_at": "2026-11-02T14:52:13.100Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04946760"
    },
    {
      "nct_id": "NCT02100579",
      "title": "Ultrasound-guided Adductor Canal Block for Total Knee Replacement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Complications; Arthroplasty",
        "Knee Injuries"
      ],
      "interventions": [
        {
          "name": "Bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Preservative free normal saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "40 Years to 75 Years"
      },
      "enrollment_count": 40,
      "start_date": "2014-03",
      "completion_date": "2015-12",
      "has_results": true,
      "last_update_posted_date": "2017-07-11",
      "last_synced_at": "2026-11-02T14:52:13.100Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02100579"
    }
  ]
}