{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sham+Comparison&page=2",
    "query": {
      "intervention": "Sham Comparison",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sham+Comparison&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-05T00:32:35.095Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04144972",
      "title": "Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spinal Cord Injuries",
        "Nerve Injury",
        "Pain, Postoperative",
        "Post Herpetic Neuralgia",
        "Complex Regional Pain Syndromes",
        "Post-Stroke Pain",
        "Post Radiation Brain Injury",
        "Post Radiation Plexopathy",
        "Nerve Root Avulsion"
      ],
      "interventions": [
        {
          "name": "Medtronic Summit RC+S or Percept RC",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "22 Years to 80 Years"
      },
      "enrollment_count": 12,
      "start_date": "2019-10-24",
      "completion_date": "2030-10-24",
      "has_results": false,
      "last_update_posted_date": "2026-07-31",
      "last_synced_at": "2026-09-05T00:32:35.095Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04144972"
    },
    {
      "nct_id": "NCT03777137",
      "title": "The Effect of Transcutaneous Magnetic Stimulation on Acute Pain.",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pain Perception"
      ],
      "interventions": [
        {
          "name": "TMS (Rapid2, Magstim Corp)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 0,
      "start_date": "2021-10-01",
      "completion_date": "2027-07-01",
      "has_results": false,
      "last_update_posted_date": "2021-10-14",
      "last_synced_at": "2026-09-05T00:32:35.095Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03777137"
    },
    {
      "nct_id": "NCT02397785",
      "title": "Intra-vaginal Electrical Stimulation Device Compared to Sham Device for Chronic Pelvic Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pelvic Pain"
      ],
      "interventions": [
        {
          "name": "ApexM",
          "type": "DEVICE"
        },
        {
          "name": "Sham Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 58,
      "start_date": "2015-04",
      "completion_date": "2017-06",
      "has_results": true,
      "last_update_posted_date": "2019-07-26",
      "last_synced_at": "2026-09-05T00:32:35.095Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02397785"
    },
    {
      "nct_id": "NCT01940887",
      "title": "A Phase 3 Safety and Efficacy Study of Fovista® (E10030) Intravitreous Administration in Combination With Either Avastin® or Eylea® Compared to Avastin® or Eylea® Monotherapy",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Age-Related Macular Degeneration"
      ],
      "interventions": [
        {
          "name": "E10030",
          "type": "DRUG"
        },
        {
          "name": "bevacizumab or aflibercept",
          "type": "DRUG"
        },
        {
          "name": "E10030 sham injection",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Ophthotech Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 645,
      "start_date": "2014-05",
      "completion_date": "2017-09",
      "has_results": true,
      "last_update_posted_date": "2024-10-31",
      "last_synced_at": "2026-09-05T00:32:35.095Z",
      "location_count": 100,
      "location_summary": "Gilbert, Arizona • Phoenix, Arizona • Tucson, Arizona + 88 more",
      "locations": [
        {
          "city": "Gilbert",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Campbell",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01940887"
    },
    {
      "nct_id": "NCT06376994",
      "title": "Multi-Center Clean Air Randomized Controlled Trial in COPD",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Chronic Obstructive Pulmonary Disease (COPD)"
      ],
      "interventions": [
        {
          "name": "Air cleaner",
          "type": "DEVICE"
        },
        {
          "name": "Sham air cleaner",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "JHSPH Center for Clinical Trials",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 770,
      "start_date": "2024-05-24",
      "completion_date": "2029-08-31",
      "has_results": false,
      "last_update_posted_date": "2026-07-31",
      "last_synced_at": "2026-09-05T00:32:35.095Z",
      "location_count": 11,
      "location_summary": "Birmingham, Alabama • Los Angeles, California • Iowa City, Iowa + 7 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Iowa City",
          "state": "Iowa"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06376994"
    },
    {
      "nct_id": "NCT07498270",
      "title": "Location- and Frequency-Dependent Effects of Thalamic Temporal Interference Stimulation During Sleep",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy Adult Participants",
        "Healthy Participants"
      ],
      "interventions": [
        {
          "name": "Magnetic Resonance Imaging (MRI)",
          "type": "OTHER"
        },
        {
          "name": "Broad thalamic stimulation (TI-TES)",
          "type": "DEVICE"
        },
        {
          "name": "Carrier only SHAM stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Anterior thalamic stimulation (TI-TES)",
          "type": "DEVICE"
        },
        {
          "name": "Posterior thalamic stimulation (TI-TES)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 24,
      "start_date": "2026-06-05",
      "completion_date": "2028-02",
      "has_results": false,
      "last_update_posted_date": "2026-08-10",
      "last_synced_at": "2026-09-05T00:32:35.095Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07498270"
    },
    {
      "nct_id": "NCT07767006",
      "title": "Neuromodulation for Patients With Parkinson's Disease",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Adults With Parkinson's Disease"
      ],
      "interventions": [
        {
          "name": "tDCS combined with TUS",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Felipe Fregni, MD, PhD, MPH",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "40 Years to 85 Years"
      },
      "enrollment_count": 116,
      "start_date": "2026-10-01",
      "completion_date": "2032-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-08-17",
      "last_synced_at": "2026-09-05T00:32:35.095Z",
      "location_count": 1,
      "location_summary": "Cambridge, Massachusetts",
      "locations": [
        {
          "city": "Cambridge",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07767006"
    },
    {
      "nct_id": "NCT03319134",
      "title": "Investigating the Neural Correlates in Memory Retrieval After HD-tDCS",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy Adults"
      ],
      "interventions": [
        {
          "name": "active anodal HD-tDCS",
          "type": "DEVICE"
        },
        {
          "name": "sham HD-tDCS",
          "type": "DEVICE"
        },
        {
          "name": "active cathodal HD-tDCS",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The University of Texas at Dallas",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 45,
      "start_date": "2017-09-18",
      "completion_date": "2020-01-30",
      "has_results": true,
      "last_update_posted_date": "2020-08-26",
      "last_synced_at": "2026-09-05T00:32:35.095Z",
      "location_count": 1,
      "location_summary": "Richardson, Texas",
      "locations": [
        {
          "city": "Richardson",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03319134"
    },
    {
      "nct_id": "NCT02680158",
      "title": "A Study to Evaluate the Safety and Effectiveness of Oculeve Intranasal Lacrimal Neurostimulator in Participants With Dry Eye Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dry Eye Syndrome",
        "Keratoconjunctivitis Sicca"
      ],
      "interventions": [
        {
          "name": "Oculeve Intranasal",
          "type": "DEVICE"
        },
        {
          "name": "Sham",
          "type": "DEVICE"
        },
        {
          "name": "Oculeve Extranasal",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Oculeve, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 48,
      "start_date": "2016-01-31",
      "completion_date": "2016-03-31",
      "has_results": true,
      "last_update_posted_date": "2019-04-26",
      "last_synced_at": "2026-09-05T00:32:35.095Z",
      "location_count": 2,
      "location_summary": "Waterbury, Connecticut • Norfolk, Virginia",
      "locations": [
        {
          "city": "Waterbury",
          "state": "Connecticut"
        },
        {
          "city": "Norfolk",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02680158"
    },
    {
      "nct_id": "NCT00750191",
      "title": "Placebo-controlled Trial of Transdiscal Radiofrequency Annuloplasty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Lower Back Pain"
      ],
      "interventions": [
        {
          "name": "The Transdiscal Radiofrequency Annuloplasty",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Baylis Medical Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 64,
      "start_date": "2007-09",
      "completion_date": "2012-09",
      "has_results": true,
      "last_update_posted_date": "2014-01-08",
      "last_synced_at": "2026-09-05T00:32:35.095Z",
      "location_count": 2,
      "location_summary": "Winston-Salem, North Carolina • Cleveland, Ohio",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00750191"
    }
  ]
}