{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sham+Control+Group&page=6",
    "query": {
      "intervention": "Sham Control Group",
      "page": 6
    },
    "page_size": 10
  },
  "pagination": {
    "page": 6,
    "page_size": 10,
    "total_count": 1167,
    "total_pages": 117,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sham+Control+Group&page=7&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sham+Control+Group&page=5&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-27T15:44:26.449Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04065490",
      "title": "Study of Photobiomodulation to Treat Dry Age-Related Macular Degeneration (LIGHTSITE III)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dry Age-related Macular Degeneration"
      ],
      "interventions": [
        {
          "name": "Valeda Light Delivery System",
          "type": "DEVICE"
        },
        {
          "name": "Valeda Light Delivery System Sham Mode",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "LumiThera, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2019-09-23",
      "completion_date": "2024-11-01",
      "has_results": true,
      "last_update_posted_date": "2026-10-08",
      "last_synced_at": "2026-10-27T15:44:26.449Z",
      "location_count": 10,
      "location_summary": "Beverly Hills, California • Palo Alto, California • Altamonte Springs, Florida + 7 more",
      "locations": [
        {
          "city": "Beverly Hills",
          "state": "California"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Altamonte Springs",
          "state": "Florida"
        },
        {
          "city": "Hagerstown",
          "state": "Maryland"
        },
        {
          "city": "Cherry Hill",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04065490"
    },
    {
      "nct_id": "NCT02132520",
      "title": "A Brain Centered Neuroengineering Approach for Motor Recovery After Stroke: Combined rTMS and BCI Training",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hemiparesis",
        "Stroke"
      ],
      "interventions": [
        {
          "name": "rTMS",
          "type": "DEVICE"
        },
        {
          "name": "BCI Training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 3,
      "start_date": "2014-03",
      "completion_date": "2017-06",
      "has_results": true,
      "last_update_posted_date": "2019-11-01",
      "last_synced_at": "2026-10-27T15:44:26.449Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02132520"
    },
    {
      "nct_id": "NCT06874361",
      "title": "Cooling to Alleviate Migraine #3",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Migraine With or Without Aura",
        "Migraine",
        "Migraine Headache"
      ],
      "interventions": [
        {
          "name": "Mi-Helper",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Mi-Helper, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 156,
      "start_date": "2025-03-24",
      "completion_date": "2025-12-15",
      "has_results": true,
      "last_update_posted_date": "2026-02-10",
      "last_synced_at": "2026-10-27T15:44:26.449Z",
      "location_count": 1,
      "location_summary": "Indian Harbour Beach, Florida",
      "locations": [
        {
          "city": "Indian Harbour Beach",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06874361"
    },
    {
      "nct_id": "NCT02193373",
      "title": "Study of Osteopathic Manipulative Medicine on the Autonomic Nervous System",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteopathic Manual Manipulation of Neurovascular Regulation"
      ],
      "interventions": [
        {
          "name": "Osteopathic Manual Medicine",
          "type": "OTHER"
        },
        {
          "name": "Sham",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "New York Institute of Technology",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "20 Years to 50 Years"
      },
      "enrollment_count": 126,
      "start_date": "2014-06",
      "completion_date": "2018-05",
      "has_results": false,
      "last_update_posted_date": "2019-07-05",
      "last_synced_at": "2026-10-27T15:44:26.449Z",
      "location_count": 1,
      "location_summary": "Old Westbury, New York",
      "locations": [
        {
          "city": "Old Westbury",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02193373"
    },
    {
      "nct_id": "NCT06608797",
      "title": "Testing the Feasibility of Computer-based Cognitive Training in Individuals with Multiple Sclerosis Living in the Community",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Multiple Sclerosis"
      ],
      "interventions": [
        {
          "name": "Learning and memory training",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sham Comparator",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Kessler Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "19 Years to 65 Years"
      },
      "enrollment_count": 40,
      "start_date": "2024-09-30",
      "completion_date": "2025-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-02-21",
      "last_synced_at": "2026-10-27T15:44:26.449Z",
      "location_count": 1,
      "location_summary": "East Hanover, New Jersey",
      "locations": [
        {
          "city": "East Hanover",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06608797"
    },
    {
      "nct_id": "NCT07387315",
      "title": "A Randomized, Placebo-controlled Trial of Nitrous Oxide During In-office Bladder Botox Injections",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Overactive Bladder",
        "Neurogenic Bladder",
        "Urge Incontinence",
        "Pain",
        "Urinary Incontinence",
        "Urinary Bladder, Overactive",
        "Urinary Bladder, Neurogenic",
        "Urinary Bladder Neurogenesis",
        "Urinary Incontinence, Urge",
        "Pelvic Floor Disorders"
      ],
      "interventions": [
        {
          "name": "Pro-Nox Nitrous Oxide/Oxygen Delivery System",
          "type": "DRUG"
        },
        {
          "name": "Standard Care for Bladder Botox Injection",
          "type": "DRUG"
        },
        {
          "name": "Sham Mask",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "TriHealth Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 96,
      "start_date": "2026-02",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-02-04",
      "last_synced_at": "2026-10-27T15:44:26.449Z",
      "location_count": 2,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07387315"
    },
    {
      "nct_id": "NCT04862468",
      "title": "Perivenous Dexamethasone Therapy: Examining Reduction of Inflammation After Thrombus Removal to Yield Benefit in Acute Femoropopliteal DVT",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Thrombosis, Deep Vein",
        "Iliofemoral; Thrombosis"
      ],
      "interventions": [
        {
          "name": "Perivascular dexamethasone",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Perivascular sham",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Mercator MedSystems, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 80,
      "start_date": "2021-10-29",
      "completion_date": "2029-02-01",
      "has_results": false,
      "last_update_posted_date": "2026-09-25",
      "last_synced_at": "2026-10-27T15:44:26.449Z",
      "location_count": 20,
      "location_summary": "Scottsdale, Arizona • Orange, California • Darien, Connecticut + 16 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "Darien",
          "state": "Connecticut"
        },
        {
          "city": "Atlantis",
          "state": "Florida"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04862468"
    },
    {
      "nct_id": "NCT04855643",
      "title": "Home-based tDCS for Apathy in Alzheimer's Disease",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alzheimer Disease and Related Dementias"
      ],
      "interventions": [
        {
          "name": "home-based active tDCS",
          "type": "DEVICE"
        },
        {
          "name": "home-based sham tDCS",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 3,
      "start_date": "2021-08-20",
      "completion_date": "2022-07-10",
      "has_results": true,
      "last_update_posted_date": "2024-04-23",
      "last_synced_at": "2026-10-27T15:44:26.449Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04855643"
    },
    {
      "nct_id": "NCT06659445",
      "title": "Study to Evaluate Efficacy and Safety of ONL1204 in Patients With GA Associated With AMD",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Geographic Atrophy (GA)",
        "Age - Related Macular Degeneration (AMD)"
      ],
      "interventions": [
        {
          "name": "ONL1204 Opthalmic solution",
          "type": "DRUG"
        },
        {
          "name": "Avacincaptad Pegol intravitreal solution",
          "type": "DRUG"
        },
        {
          "name": "Sham",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "ONL Therapeutics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "55 Years and older"
      },
      "enrollment_count": 324,
      "start_date": "2025-10-28",
      "completion_date": "2028-11",
      "has_results": false,
      "last_update_posted_date": "2026-09-10",
      "last_synced_at": "2026-10-27T15:44:26.449Z",
      "location_count": 56,
      "location_summary": "Gilbert, Arizona • Phoenix, Arizona • Bakersfield, California + 50 more",
      "locations": [
        {
          "city": "Gilbert",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Bakersfield",
          "state": "California"
        },
        {
          "city": "Beverly Hills",
          "state": "California"
        },
        {
          "city": "Glendale",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06659445"
    },
    {
      "nct_id": "NCT03449667",
      "title": "Cryoanalgesia to Treat Post-Amputation Phantom Limb Pain: A Department of Defense Funded Multicenter Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Post-Amputation Phantom Limb Pain"
      ],
      "interventions": [
        {
          "name": "Cryoneurolysis",
          "type": "DEVICE"
        },
        {
          "name": "Sham Comparator",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 144,
      "start_date": "2018-03-23",
      "completion_date": "2022-03-17",
      "has_results": true,
      "last_update_posted_date": "2023-02-17",
      "last_synced_at": "2026-10-27T15:44:26.449Z",
      "location_count": 6,
      "location_summary": "Palo Alto, California • San Diego, California • Gainesville, Florida + 2 more",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03449667"
    }
  ]
}