{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sham+Injection&page=3", "query": { "intervention": "Sham Injection", "page": 3 }, "page_size": 10 }, "pagination": { "page": 3, "page_size": 10, "total_count": 372, "total_pages": 38, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sham+Injection&page=4&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sham+Injection&page=2&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-18T18:34:28.297Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT06007690", "title": "A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Choroidal Melanoma", "Indeterminate Lesions", "Uveal Melanoma", "Ocular Melanoma" ], "interventions": [ { "name": "Bel-sar", "type": "DRUG" }, { "name": "Suprachoroidal Microinjector", "type": "DEVICE" }, { "name": "Infrared Laser", "type": "DEVICE" }, { "name": "Sham Infrared Laser", "type": "DEVICE" }, { "name": "Sham Microinjector", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "Aura Biosciences", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 108, "start_date": "2023-12-06", "completion_date": "2028-08-15", "has_results": false, "last_update_posted_date": "2026-10-13", "last_synced_at": "2026-10-18T18:34:28.297Z", "location_count": 25, "location_summary": "Los Angeles, California • Palo Alto, California • Sacramento, California + 20 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Palo Alto", "state": "California" }, { "city": "Sacramento", "state": "California" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT06007690" }, { "nct_id": "NCT00400634", "title": "Double-Blind, Multicenter, Sham Surgery Controlled Study of CERE-120 in Subjects With Idiopathic Parkinson's Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Idiopathic Parkinson's Disease" ], "interventions": [ { "name": "CERE-120 (Adeno-Associated Virus Serotype 2 [AAV2]-Neurturin [NTN])", "type": "DRUG" }, { "name": "Sham Surgery", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "Sangamo Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "35 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "35 Years to 75 Years" }, "enrollment_count": 58, "start_date": "2006-11", "completion_date": "2008-11", "has_results": true, "last_update_posted_date": "2022-11-10", "last_synced_at": "2026-10-18T18:34:28.297Z", "location_count": 9, "location_summary": "Birmingham, Alabama • San Francisco, California • Chicago, Illinois + 6 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "San Francisco", "state": "California" }, { "city": "Chicago", "state": "Illinois" }, { "city": "New York", "state": "New York" }, { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00400634" }, { "nct_id": "NCT05642312", "title": "A Study to Investigate Vamikibart in Participants With Uveitic Macular Edema", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Uveitic Macular Edema" ], "interventions": [ { "name": "Vamikibart", "type": "DRUG" }, { "name": "Sham", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Hoffmann-La Roche", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 245, "start_date": "2023-01-09", "completion_date": "2025-07-09", "has_results": false, "last_update_posted_date": "2025-11-21", "last_synced_at": "2026-10-18T18:34:28.297Z", "location_count": 16, "location_summary": "Los Angeles, California • Lakewood, Colorado • St. Petersburg, Florida + 13 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Lakewood", "state": "Colorado" }, { "city": "St. Petersburg", "state": "Florida" }, { "city": "Hagerstown", "state": "Maryland" }, { "city": "Minneapolis", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT05642312" }, { "nct_id": "NCT05972681", "title": "The PAIN (Pelvic Area Injection for Numbness) Study", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Vaginal Laceration During Delivery" ], "interventions": [ { "name": "Bupivacaine", "type": "DRUG" }, { "name": "Epinephrine", "type": "DRUG" }, { "name": "Sham normal saline arm", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Montefiore Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 3, "start_date": "2025-04-08", "completion_date": "2025-10-19", "has_results": true, "last_update_posted_date": "2026-05-27", "last_synced_at": "2026-10-18T18:34:28.297Z", "location_count": 1, "location_summary": "The Bronx, New York", "locations": [ { "city": "The Bronx", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT05972681" }, { "nct_id": "NCT03364153", "title": "Zimura Compared to Sham in Patients With Autosomal Recessive Stargardt Disease (STGD1)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Stargardt's Macular Dystrophy" ], "interventions": [ { "name": "avacincaptad pegol", "type": "DRUG" }, { "name": "Sham", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Astellas Pharma Global Development, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "18 Years to 60 Years" }, "enrollment_count": 121, "start_date": "2018-01-12", "completion_date": "2025-03-31", "has_results": true, "last_update_posted_date": "2026-04-15", "last_synced_at": "2026-10-18T18:34:28.297Z", "location_count": 17, "location_summary": "Phoenix, Arizona • Los Angeles, California • Gainesville, Florida + 14 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Los Angeles", "state": "California" }, { "city": "Gainesville", "state": "Florida" }, { "city": "Pensacola", "state": "Florida" }, { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT03364153" }, { "nct_id": "NCT03231150", "title": "Plantar Fasciitis Randomized Clinical Control Trial", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Plantar Fascitis" ], "interventions": [ { "name": "Local Steroid Injection into the plantar heel", "type": "PROCEDURE" }, { "name": "Ultrasound Guided Injection", "type": "PROCEDURE" }, { "name": "Anatomical Guided injection", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "University of Pennsylvania", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 62, "start_date": "2017-03-28", "completion_date": "2026-10-31", "has_results": false, "last_update_posted_date": "2025-10-10", "last_synced_at": "2026-10-18T18:34:28.297Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT03231150" }, { "nct_id": "NCT06541574", "title": "Prevention of ProliFerative Vitreoretinopathy with Intravitreal MethotreXate in Primary Retinal DEtachment Repair (FIXER) Trial", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Proliferative Vitreoretinopathy", "Rhegmatogenous Retinal Detachment" ], "interventions": [ { "name": "Methotrexate Injection", "type": "DRUG" }, { "name": "Methotrexate Infusion", "type": "DRUG" }, { "name": "Sham Injection", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Cincinnati Eye Institute, Southwest Ohio", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 860, "start_date": "2024-03-01", "completion_date": "2026-06", "has_results": false, "last_update_posted_date": "2024-09-19", "last_synced_at": "2026-10-18T18:34:28.297Z", "location_count": 1, "location_summary": "Cincinnati, Ohio", "locations": [ { "city": "Cincinnati", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT06541574" }, { "nct_id": "NCT03211234", "title": "Study Assessing the Efficacy and Safety of Intravitreal Injections of DE-122 in Combination With Lucentis® Compared to Lucentis® Monotherapy in Wet Age-related Macular Degeneration Subjects", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Age-Related Macular Degeneration" ], "interventions": [ { "name": "2.0 mg DE-122 Injectable Solution + Lucentis", "type": "DRUG" }, { "name": "4.0 mg DE-122 Injectable Solution + Lucentis", "type": "DRUG" }, { "name": "Lucentis", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Santen Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "50 Years", "maximum_age": null, "sex": "ALL", "summary": "50 Years and older" }, "enrollment_count": 76, "start_date": "2017-07-05", "completion_date": "2020-01-31", "has_results": true, "last_update_posted_date": "2021-07-13", "last_synced_at": "2026-10-18T18:34:28.297Z", "location_count": 10, "location_summary": "Gilbert, Arizona • Beverly Hills, California • Mountain View, California + 7 more", "locations": [ { "city": "Gilbert", "state": "Arizona" }, { "city": "Beverly Hills", "state": "California" }, { "city": "Mountain View", "state": "California" }, { "city": "Walnut Creek", "state": "California" }, { "city": "Golden", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT03211234" }, { "nct_id": "NCT05486468", "title": "The Use of Two YUTIQ Versus Sham for Treatment of Chronic Non Infectious Intraocular Inflammation Affecting the Posterior Segment", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Uveitis", "Uveitis, Posterior", "Uveitis, Anterior", "Uveitis, Intermediate" ], "interventions": [ { "name": "Yutiq 0.18 MG Drug Implant", "type": "DRUG" }, { "name": "Sham Injection", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Texas Retina Associates", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 10, "start_date": "2022-10-05", "completion_date": "2026-03-31", "has_results": false, "last_update_posted_date": "2026-10-05", "last_synced_at": "2026-10-18T18:34:28.297Z", "location_count": 1, "location_summary": "Plano, Texas", "locations": [ { "city": "Plano", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT05486468" }, { "nct_id": "NCT03622593", "title": "A Study to Evaluate the Efficacy and Safety of Faricimab (RO6867461) in Participants With Diabetic Macular Edema", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Diabetic Macular Edema" ], "interventions": [ { "name": "Aflibercept", "type": "DRUG" }, { "name": "Faricimab", "type": "DRUG" }, { "name": "Sham Procedure", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "Hoffmann-La Roche", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 951, "start_date": "2018-10-09", "completion_date": "2023-05-31", "has_results": true, "last_update_posted_date": "2025-07-11", "last_synced_at": "2026-10-18T18:34:28.297Z", "location_count": 50, "location_summary": "Phoenix, Arizona • Springdale, Arkansas • Bakersfield, California + 44 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Springdale", "state": "Arkansas" }, { "city": "Bakersfield", "state": "California" }, { "city": "Beverly Hills", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03622593" } ] }