{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sham-Control&page=10",
    "query": {
      "intervention": "Sham-Control",
      "page": 10
    },
    "page_size": 10
  },
  "pagination": {
    "page": 10,
    "page_size": 10,
    "total_count": 1656,
    "total_pages": 166,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sham-Control&page=11&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sham-Control&page=9&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-23T10:29:24.002Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05617911",
      "title": "Clinical Comparison of Patellofemoral Pain Syndrome Outcomes After Blood Flow Restriction Therapy",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Patellofemoral Pain Syndrome",
        "Anterior Knee Pain Syndrome"
      ],
      "interventions": [
        {
          "name": "Blood Flow Restriction Cuff",
          "type": "DEVICE"
        },
        {
          "name": "Sham and standard of Care Therapy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Gaylord Hospital, Inc",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "15 Years and older"
      },
      "enrollment_count": 1,
      "start_date": "2022-11-15",
      "completion_date": "2023-10-10",
      "has_results": true,
      "last_update_posted_date": "2025-12-10",
      "last_synced_at": "2026-10-23T10:29:24.002Z",
      "location_count": 6,
      "location_summary": "Cheshire, Connecticut • Cromwell, Connecticut • Farmington, Connecticut + 2 more",
      "locations": [
        {
          "city": "Cheshire",
          "state": "Connecticut"
        },
        {
          "city": "Cromwell",
          "state": "Connecticut"
        },
        {
          "city": "Farmington",
          "state": "Connecticut"
        },
        {
          "city": "Madison",
          "state": "Connecticut"
        },
        {
          "city": "Wallingford",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05617911"
    },
    {
      "nct_id": "NCT06305039",
      "title": "Optimizing Bilateral and Single-sided-deafness Cochlear Implants for Functioning in Complex Auditory Environments",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hearing Loss",
        "Hearing Loss, Sensorineural",
        "Cochlear Hearing Loss"
      ],
      "interventions": [
        {
          "name": "Diagnostic tests of cochlear implant or acoustic hearing function",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Targeted aural rehabilitation of the poorer performing ear",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Maryland, College Park",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 300,
      "start_date": "2023-12-19",
      "completion_date": "2028-05-31",
      "has_results": false,
      "last_update_posted_date": "2025-03-28",
      "last_synced_at": "2026-10-23T10:29:24.002Z",
      "location_count": 2,
      "location_summary": "Bethesda, Maryland • College Park, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        },
        {
          "city": "College Park",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06305039"
    },
    {
      "nct_id": "NCT04055376",
      "title": "Daily Light and Sound Stimulation to Improve Brain Functions in Alzheimer's Disease",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alzheimer Disease",
        "Alzheimer Dementia"
      ],
      "interventions": [
        {
          "name": "GENUS device (Active Settings)",
          "type": "DEVICE"
        },
        {
          "name": "GENUS device (Sham Settings)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Massachusetts Institute of Technology",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "50 Years to 100 Years"
      },
      "enrollment_count": 15,
      "start_date": "2019-08-14",
      "completion_date": "2027-01-15",
      "has_results": false,
      "last_update_posted_date": "2026-05-26",
      "last_synced_at": "2026-10-23T10:29:24.002Z",
      "location_count": 1,
      "location_summary": "Cambridge, Massachusetts",
      "locations": [
        {
          "city": "Cambridge",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04055376"
    },
    {
      "nct_id": "NCT01497691",
      "title": "Noninvasive Positive Airway Pressure in the Pediatric Emergency Department for the Treatment of Acute Asthma Exacerbations",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Asthma"
      ],
      "interventions": [
        {
          "name": "NIPPV (PALMtop PTV)",
          "type": "DEVICE"
        },
        {
          "name": "Volumetric CO2 (NM3)",
          "type": "DEVICE"
        },
        {
          "name": "USCOM",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "2 Years to 18 Years"
      },
      "enrollment_count": 0,
      "start_date": "2013-01",
      "completion_date": "2013-11-19",
      "has_results": false,
      "last_update_posted_date": "2017-08-24",
      "last_synced_at": "2026-10-23T10:29:24.002Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01497691"
    },
    {
      "nct_id": "NCT00739362",
      "title": "Effects of Brain Stimulation on Food Intake and Behavioral Weight Loss Treatment",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Electric Stimulation Therapy",
        "Obesity",
        "Weight Loss",
        "Eating"
      ],
      "interventions": [
        {
          "name": "Transcranial Direct Current Stimulation (TDCS)",
          "type": "DEVICE"
        },
        {
          "name": "Sham/no-stimulation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 126,
      "start_date": "2009-01-19",
      "completion_date": "2027-01-31",
      "has_results": false,
      "last_update_posted_date": "2026-10-08",
      "last_synced_at": "2026-10-23T10:29:24.002Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00739362"
    },
    {
      "nct_id": "NCT06072924",
      "title": "K01 Impacts of Lingual Endurance Exercise",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dysphagia",
        "Dysphagia, Oropharyngeal",
        "Ischemic Stroke",
        "Stroke"
      ],
      "interventions": [
        {
          "name": "Isotonic Endurance Exercise",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sham Exercise",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 70,
      "start_date": "2023-09-01",
      "completion_date": "2028-08-31",
      "has_results": false,
      "last_update_posted_date": "2026-09-04",
      "last_synced_at": "2026-10-23T10:29:24.002Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06072924"
    },
    {
      "nct_id": "NCT06555562",
      "title": "Activating the Cholinergic Anti-Inflammatory Pathway in Healthy Volunteers and People With Inflammatory Arthritis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Psoriatic Arthritis",
        "Rheumatoid Arthritis",
        "Ankylosing Spondylitis"
      ],
      "interventions": [
        {
          "name": "Ultrasound Stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Non-active ultrasound stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Surf Therapeutics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "22 Years to 75 Years"
      },
      "enrollment_count": 16,
      "start_date": "2025-10-01",
      "completion_date": "2026-01-05",
      "has_results": false,
      "last_update_posted_date": "2026-01-07",
      "last_synced_at": "2026-10-23T10:29:24.002Z",
      "location_count": 2,
      "location_summary": "Austin, Texas • Houston, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06555562"
    },
    {
      "nct_id": "NCT07581158",
      "title": "Understanding and Targeting Self-Regulatory Control in Bulimia Nervosa",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bulimia Nervosa",
        "Feeding and Eating Disorders",
        "Mental Disorders"
      ],
      "interventions": [
        {
          "name": "Real fNIRS Neurofeedback",
          "type": "OTHER"
        },
        {
          "name": "Sham-Control fNIRS Neurofeedback",
          "type": "OTHER"
        },
        {
          "name": "SmartPhone Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Icahn School of Medicine at Mount Sinai",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 55 Years · Female only"
      },
      "enrollment_count": 40,
      "start_date": "2026-04-25",
      "completion_date": "2028-12-14",
      "has_results": false,
      "last_update_posted_date": "2026-05-12",
      "last_synced_at": "2026-10-23T10:29:24.002Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07581158"
    },
    {
      "nct_id": "NCT00475787",
      "title": "Chiropractic Management of Chronic Lower Back Pain in Older Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Low Back Pain"
      ],
      "interventions": [
        {
          "name": "Spinal Manipulation",
          "type": "PROCEDURE"
        },
        {
          "name": "Detuned Ultrasound",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "US Department of Veterans Affairs",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 136,
      "start_date": "2008-04",
      "completion_date": "2011-04",
      "has_results": true,
      "last_update_posted_date": "2014-12-30",
      "last_synced_at": "2026-10-23T10:29:24.002Z",
      "location_count": 2,
      "location_summary": "Buffalo, New York • Canandaigua, New York",
      "locations": [
        {
          "city": "Buffalo",
          "state": "New York"
        },
        {
          "city": "Canandaigua",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00475787"
    },
    {
      "nct_id": "NCT02947321",
      "title": "Genicular Radiofrequency Ablation Efficacy in Achieving Total Knee Pain Reduction Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Arthroplasty, Total",
        "Osteoarthritis",
        "Radiologic Tibiofemoral Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Genicular Nerve RFA",
          "type": "PROCEDURE"
        },
        {
          "name": "Sham Genicular Nerve RFA",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "79 Years",
        "sex": "ALL",
        "summary": "45 Years to 79 Years"
      },
      "enrollment_count": 60,
      "start_date": "2018-01-26",
      "completion_date": "2020-09-09",
      "has_results": false,
      "last_update_posted_date": "2020-10-05",
      "last_synced_at": "2026-10-23T10:29:24.002Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02947321"
    }
  ]
}