{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sham-PNS",
    "query": {
      "intervention": "Sham-PNS"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 33,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sham-PNS&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-06T16:04:30.905Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06440538",
      "title": "Rebuilding Inter-limb Transfer in Cervical SCI",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Cervical Spinal Cord Injury"
      ],
      "interventions": [
        {
          "name": "PCMS + Contralateral Motor Training",
          "type": "DEVICE"
        },
        {
          "name": "PCMS + Rest",
          "type": "DEVICE"
        },
        {
          "name": "Sham PCMS + Contralateral Motor Training",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 17,
      "start_date": "2024-02-15",
      "completion_date": "2026-07-30",
      "has_results": false,
      "last_update_posted_date": "2026-03-24",
      "last_synced_at": "2026-09-06T16:04:30.905Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06440538"
    },
    {
      "nct_id": "NCT05721261",
      "title": "Regeneration of Acutely Injured Nerves With Temporary Electrical Stimulation",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nerve Injury"
      ],
      "interventions": [
        {
          "name": "Temporary Peripheral Nerve Stimulation System",
          "type": "DEVICE"
        },
        {
          "name": "Sham Temporary Peripheral Nerve Stimulation System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Epineuron Technologies Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 110,
      "start_date": "2023-08-11",
      "completion_date": "2026-09",
      "has_results": false,
      "last_update_posted_date": "2026-03-16",
      "last_synced_at": "2026-09-06T16:04:30.905Z",
      "location_count": 6,
      "location_summary": "Gainesville, Florida • Orlando, Florida • New Orleans, Louisiana + 3 more",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "New Orleans",
          "state": "Louisiana"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "York",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05721261"
    },
    {
      "nct_id": "NCT03481725",
      "title": "Ultrasound-Guided Percutaneous Peripheral Nerve Stimulation: A Department of Defense Funded Multicenter Pilot Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Rotator Cuff Repair",
        "Anterior Cruciate Ligament Reconstruction",
        "Ankle Arthrodesis or Arthroplasty",
        "Hallux Valgus Correction"
      ],
      "interventions": [
        {
          "name": "ACTIVE peripheral nerve stimulation with a percutaneously inserted lead and wearable stimulator (SPR Therapeutics, Cleveland, Ohio)",
          "type": "DEVICE"
        },
        {
          "name": "SHAM peripheral nerve stimulation with a percutaneously inserted lead and wearable SHAM stimulator (SPR Therapeutics, Cleveland, Ohio)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 65,
      "start_date": "2018-07-14",
      "completion_date": "2021-01-07",
      "has_results": true,
      "last_update_posted_date": "2021-03-18",
      "last_synced_at": "2026-09-06T16:04:30.905Z",
      "location_count": 6,
      "location_summary": "San Diego, California • Bethesda, Maryland • Fort Bragg, North Carolina + 2 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Bethesda",
          "state": "Maryland"
        },
        {
          "city": "Fort Bragg",
          "state": "North Carolina"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03481725"
    },
    {
      "nct_id": "NCT04244227",
      "title": "Pilot Research on Opioid Use Disorder",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Opioid-use Disorder"
      ],
      "interventions": [
        {
          "name": "Empower Neuromodulation System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Theranova, L.L.C.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 10,
      "start_date": "2020-03-10",
      "completion_date": "2022-02-15",
      "has_results": false,
      "last_update_posted_date": "2022-02-21",
      "last_synced_at": "2026-09-06T16:04:30.905Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04244227"
    },
    {
      "nct_id": "NCT05421208",
      "title": "Cardiovascular Autonomic and Immune Mechanism of Post COVID-19 Tachycardia Syndrome",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Post-acute COVID-19 Syndrome",
        "Postural Tachycardia Syndrome (POTS)",
        "Long COVID",
        "SARS CoV 2 Infection"
      ],
      "interventions": [
        {
          "name": "Levels of inflammatory cytokine ( IL-6) in post-COVID-19 POTS and controls",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Levels of inflammatory cytokine ( IL-6) in controls",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Effect on inflammation after chronic PNS stimulation",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2022-06-01",
      "completion_date": "2027-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-07-15",
      "last_synced_at": "2026-09-06T16:04:30.905Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05421208"
    },
    {
      "nct_id": "NCT07336355",
      "title": "Feasibility of an Analgesic Device Enabling Local Anesthetic Delivery and Neuromodulation After Knee Surgery",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Arthropathy"
      ],
      "interventions": [
        {
          "name": "Percutaneous peripheral nerve stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2026-03-14",
      "completion_date": "2026-03-14",
      "has_results": false,
      "last_update_posted_date": "2026-03-17",
      "last_synced_at": "2026-09-06T16:04:30.905Z",
      "location_count": 1,
      "location_summary": "La Jolla, California",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07336355"
    },
    {
      "nct_id": "NCT05653583",
      "title": "Peripheral Nerve Stimulation Therapy for Atrial Fibrillation",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Atrial Fibrillation"
      ],
      "interventions": [
        {
          "name": "Wrist Device",
          "type": "DEVICE"
        },
        {
          "name": "Ear Device",
          "type": "DEVICE"
        },
        {
          "name": "Sham Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Cala Health, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "79 Years",
        "sex": "ALL",
        "summary": "22 Years to 79 Years"
      },
      "enrollment_count": 30,
      "start_date": "2023-03",
      "completion_date": "2023-12",
      "has_results": false,
      "last_update_posted_date": "2023-02-08",
      "last_synced_at": "2026-09-06T16:04:30.905Z",
      "location_count": 2,
      "location_summary": "Rochester, Minnesota • Charleston, South Carolina",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05653583"
    },
    {
      "nct_id": "NCT04901481",
      "title": "Empower Neuromodulation System - Pilot Study for Anxiety Treatment",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Generalized Anxiety Disorder"
      ],
      "interventions": [
        {
          "name": "Empower Neuromodulation System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Theranova, L.L.C.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 18,
      "start_date": "2021-09-17",
      "completion_date": "2023-05-17",
      "has_results": true,
      "last_update_posted_date": "2024-06-20",
      "last_synced_at": "2026-09-06T16:04:30.905Z",
      "location_count": 1,
      "location_summary": "Omaha, Nebraska",
      "locations": [
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04901481"
    },
    {
      "nct_id": "NCT04807764",
      "title": "Transspinal Stimulation Plus Locomotor Training for SCI",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spinal Cord Injuries",
        "Paraplegia, Spinal",
        "Tetraplegia/Tetraparesis",
        "Paraplegia, Spastic"
      ],
      "interventions": [
        {
          "name": "Standing transspinal stimulation followed by robotic gait training",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Lying transspinal stimulation followed by robotic gait training",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Standing sham transspinal stimulation followed by robotic gait training",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT",
        "OTHER"
      ],
      "sponsor": "City University of New York",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 14,
      "start_date": "2021-08-01",
      "completion_date": "2024-12-31",
      "has_results": true,
      "last_update_posted_date": "2026-08-18",
      "last_synced_at": "2026-09-06T16:04:30.905Z",
      "location_count": 2,
      "location_summary": "Staten Island, New York • The Bronx, New York",
      "locations": [
        {
          "city": "Staten Island",
          "state": "New York"
        },
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04807764"
    },
    {
      "nct_id": "NCT04576013",
      "title": "Peripheral Nerve Stimulation to Improve Upper Extremity Function After Severe Stroke",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stroke"
      ],
      "interventions": [
        {
          "name": "Peripheral nerve stimulation (PNS)",
          "type": "DEVICE"
        },
        {
          "name": "Intensive upper extremity motor training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Kentucky",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 12,
      "start_date": "2016-02-23",
      "completion_date": "2021-02-22",
      "has_results": false,
      "last_update_posted_date": "2021-02-25",
      "last_synced_at": "2026-09-06T16:04:30.905Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04576013"
    }
  ]
}