{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Signal+On",
    "query": {
      "intervention": "Signal On"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 301,
    "total_pages": 31,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Signal+On&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-08T11:28:34.191Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06355284",
      "title": "Overcontrol and Suicide in PTSD",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Compulsive Personality Disorder",
        "Stress Disorders, Post-Traumatic"
      ],
      "interventions": [
        {
          "name": "Functional MRI",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 59,
      "start_date": "2024-07-01",
      "completion_date": "2026-04-30",
      "has_results": false,
      "last_update_posted_date": "2026-07-07",
      "last_synced_at": "2026-09-08T11:28:34.191Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06355284"
    },
    {
      "nct_id": "NCT05592613",
      "title": "Next Generation Ingestible Sensors for Medication Adherence Measurement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "HIV Infection",
        "Adherence, Medication",
        "Adherence, Treatment",
        "Pre-Exposure Prophylaxis",
        "Antiretroviral Therapy"
      ],
      "interventions": [
        {
          "name": "Next-generation Reader and ID-Cap System",
          "type": "DEVICE"
        },
        {
          "name": "Truvada for pre-exposure prophylaxis (PrEP)",
          "type": "DRUG"
        },
        {
          "name": "Biktarvy for antiretroviral therapy (ART)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 15,
      "start_date": "2023-02-06",
      "completion_date": "2024-07-25",
      "has_results": false,
      "last_update_posted_date": "2024-09-25",
      "last_synced_at": "2026-09-08T11:28:34.191Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05592613"
    },
    {
      "nct_id": "NCT05478213",
      "title": "Ventricular Tachycardia Mechanisms",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ventricular Tachycardia"
      ],
      "interventions": [
        {
          "name": "Monophasic Action Potential (MAP) Catheter",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2022-10-25",
      "completion_date": "2027-05",
      "has_results": false,
      "last_update_posted_date": "2026-06-30",
      "last_synced_at": "2026-09-08T11:28:34.191Z",
      "location_count": 3,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05478213"
    },
    {
      "nct_id": "NCT07361562",
      "title": "A Study of a Selective ERBB2 Inhibitor (CGT4255), in Patients With Advanced Solid Tumors",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Advanced Solid Tumor, Adult",
        "ERBB2 Altered Breast Cancer",
        "ERBB2 Gene Amplification",
        "HER2 Overexpression",
        "Non-Small Cell Lung Cancer",
        "HER2"
      ],
      "interventions": [
        {
          "name": "CGT4255",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Cogent Biosciences, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2025-12-30",
      "completion_date": "2028-11",
      "has_results": false,
      "last_update_posted_date": "2026-09-04",
      "last_synced_at": "2026-09-08T11:28:34.191Z",
      "location_count": 15,
      "location_summary": "Scottsdale, Arizona • New Haven, Connecticut • Jacksonville, Florida + 11 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07361562"
    },
    {
      "nct_id": "NCT06883981",
      "title": "Capturing Autobiographical Memory Formation in Real World Spaces Using Multimodal Recordings",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Epilepsy",
        "Autobiographical Memory"
      ],
      "interventions": [
        {
          "name": "Free and Cued Recall Memory. Temporal Sequence and Spatial Memory",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2025-01-30",
      "completion_date": "2028-03",
      "has_results": false,
      "last_update_posted_date": "2025-04-08",
      "last_synced_at": "2026-09-08T11:28:34.191Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06883981"
    },
    {
      "nct_id": "NCT06611397",
      "title": "Discogen for Low Back Pain",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Disc Herniation"
      ],
      "interventions": [
        {
          "name": "Discogen Low pulsed ultrasound treatment",
          "type": "DEVICE"
        },
        {
          "name": "Discogen Sham Treatment",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "21 Years to 75 Years"
      },
      "enrollment_count": 5,
      "start_date": "2025-03-15",
      "completion_date": "2027-08",
      "has_results": false,
      "last_update_posted_date": "2026-04-09",
      "last_synced_at": "2026-09-08T11:28:34.191Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06611397"
    },
    {
      "nct_id": "NCT01719562",
      "title": "MRI in Detecting Heart Damage in Patients With Cancer Receiving Chemotherapy With Exercise Capacity Addendum",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiac Toxicity",
        "Malignant Neoplasm",
        "Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Magnetic resonance imaging",
          "type": "PROCEDURE"
        },
        {
          "name": "Physical Activity",
          "type": "OTHER"
        },
        {
          "name": "Healthy Living",
          "type": "OTHER"
        },
        {
          "name": "Cardiopulmonary Exercise Testing (CPET)",
          "type": "DEVICE"
        },
        {
          "name": "Questionnaire Administration",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 28,
      "start_date": "2013-01-01",
      "completion_date": "2022-03-08",
      "has_results": true,
      "last_update_posted_date": "2023-05-19",
      "last_synced_at": "2026-09-08T11:28:34.191Z",
      "location_count": 2,
      "location_summary": "Winston-Salem, North Carolina • Richmond, Virginia",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        },
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01719562"
    },
    {
      "nct_id": "NCT07279441",
      "title": "Cochlear Implants and Listening Effort: the Interaction of Cognitive and Sensory Constraints",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cochlear Implant Users"
      ],
      "interventions": [
        {
          "name": "Experiment 1: Syntactic and Semantic Context",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Experiment 2: False Hearing and Context Overuse",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Experiment 3: Two-Sentence Problem",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Experiment 4: Cascading Effects on Discourse Comprehension",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Experiment 5: Self-Paced Discourse Comprehension",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Experiment 6: Clinical Application",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 460,
      "start_date": "2025-01-02",
      "completion_date": "2030-01-02",
      "has_results": false,
      "last_update_posted_date": "2025-12-12",
      "last_synced_at": "2026-09-08T11:28:34.191Z",
      "location_count": 2,
      "location_summary": "Waltham, Massachusetts • New York, New York",
      "locations": [
        {
          "city": "Waltham",
          "state": "Massachusetts"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07279441"
    },
    {
      "nct_id": "NCT04934956",
      "title": "Increasing Gait Automaticity in Older Adults by Exploiting Locomotor Adaptation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Community Mobility of Older Adults",
        "Locomotor Adaptability",
        "Gait Automaticity"
      ],
      "interventions": [
        {
          "name": "Split-belt walking",
          "type": "OTHER"
        },
        {
          "name": "Multiple transitions between split-belt and tied-belt walking",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 44,
      "start_date": "2021-11-08",
      "completion_date": "2025-05-10",
      "has_results": false,
      "last_update_posted_date": "2026-06-25",
      "last_synced_at": "2026-09-08T11:28:34.191Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04934956"
    },
    {
      "nct_id": "NCT07215429",
      "title": "SpO2 Validation Study-Philips Optimus",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pulse Oximetry, Oxygen Measurements, SpO2"
      ],
      "interventions": [
        {
          "name": "No intervention",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Philips Clinical & Medical Affairs Global",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 24,
      "start_date": "2025-09-09",
      "completion_date": "2025-09-19",
      "has_results": false,
      "last_update_posted_date": "2026-04-13",
      "last_synced_at": "2026-09-08T11:28:34.191Z",
      "location_count": 1,
      "location_summary": "Louisville, Colorado",
      "locations": [
        {
          "city": "Louisville",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07215429"
    }
  ]
}