{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Silicone+Hydrogel+Contact+Lens", "query": { "intervention": "Silicone Hydrogel Contact Lens" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 136, "total_pages": 14, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Silicone+Hydrogel+Contact+Lens&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-28T18:55:30.334Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01966770", "title": "Clinical Evaluation of Hydrogels vs Silicone Hydrogel Contact Lenses", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Myopia" ], "interventions": [ { "name": "Pair 1 (ocufilcon D / ocufilcon D)", "type": "DEVICE" }, { "name": "Pair 2 (ocufilcon D / enfilcon A)", "type": "DEVICE" }, { "name": "Pair 3 (ocufilcon D / comfilcon A)", "type": "DEVICE" }, { "name": "Pair 4 (methafilcon A / methafilcon A)", "type": "DEVICE" }, { "name": "Pair 5 (methafilcon A / comfilcon A)", "type": "DEVICE" }, { "name": "Pair 6 (omafilcon A / comfilcon A)", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "CooperVision, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "40 Years", "sex": "ALL", "summary": "18 Years to 40 Years" }, "enrollment_count": 20, "start_date": "2013-10", "completion_date": "2013-11", "has_results": true, "last_update_posted_date": "2020-07-30", "last_synced_at": "2026-09-28T18:55:30.334Z", "location_count": 1, "location_summary": "Berkeley, California", "locations": [ { "city": "Berkeley", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01966770" }, { "nct_id": "NCT01100424", "title": "Assessment of Tear Film-Based Proteins Associated With Care Solution Induced Corneal Staining", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Corneal Staining" ], "interventions": [ { "name": "Opti-Free RepleniSH", "type": "DEVICE" }, { "name": "ReNu MultiPlus", "type": "DEVICE" }, { "name": "Balafilcon A", "type": "DEVICE" }, { "name": "Unisol 4", "type": "OTHER" } ], "intervention_types": [ "DEVICE", "OTHER" ], "sponsor": "Alcon Research", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "35 Years", "sex": "ALL", "summary": "18 Years to 35 Years" }, "enrollment_count": 60, "start_date": "2010-03", "completion_date": "2010-09", "has_results": false, "last_update_posted_date": "2012-10-23", "last_synced_at": "2026-09-28T18:55:30.334Z", "location_count": 1, "location_summary": "Fort Worth, Texas", "locations": [ { "city": "Fort Worth", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01100424" }, { "nct_id": "NCT04532099", "title": "Clinical Comparison of Two Daily Wear Frequent Replacement Silicone Hydrogel Soft Contact Lenses", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Refractive Errors", "Ametropia" ], "interventions": [ { "name": "Lehfilcon A contact lenses", "type": "DEVICE" }, { "name": "Senofilcon A contact lenses", "type": "DEVICE" }, { "name": "Comfilcon A contact lenses", "type": "DEVICE" }, { "name": "Hydrogen peroxide-based cleaning and disinfecting solution", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Alcon Research", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 132, "start_date": "2020-09-09", "completion_date": "2021-05-04", "has_results": true, "last_update_posted_date": "2022-05-03", "last_synced_at": "2026-09-28T18:55:30.334Z", "location_count": 4, "location_summary": "Longwood, Florida • Maitland, Florida • Warwick, Rhode Island + 1 more", "locations": [ { "city": "Longwood", "state": "Florida" }, { "city": "Maitland", "state": "Florida" }, { "city": "Warwick", "state": "Rhode Island" }, { "city": "Memphis", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT04532099" }, { "nct_id": "NCT05827224", "title": "Air Optix Daily Wear Contact Lenses", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Refractive Errors" ], "interventions": [ { "name": "Lotrafilcon B spherical soft contact lenses", "type": "DEVICE" }, { "name": "Lotrafilcon B spherical soft contact lenses with comfort additive", "type": "DEVICE" }, { "name": "Lotrafilcon B toric soft contact lenses with comfort additive", "type": "DEVICE" }, { "name": "Comfilcon A spherical soft contact lenses", "type": "DEVICE" }, { "name": "Comfilcon A toric soft contact lenses", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Alcon Research", "sponsor_class": "INDUSTRY", "healthy_volunteers": null, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 312, "start_date": "2023-08-02", "completion_date": "2024-07-17", "has_results": false, "last_update_posted_date": "2024-08-15", "last_synced_at": "2026-09-28T18:55:30.334Z", "location_count": 5, "location_summary": "Orlando, Florida • Medina, Minnesota • St Louis, Missouri + 2 more", "locations": [ { "city": "Orlando", "state": "Florida" }, { "city": "Medina", "state": "Minnesota" }, { "city": "St Louis", "state": "Missouri" }, { "city": "Nashville", "state": "Tennessee" }, { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT05827224" }, { "nct_id": "NCT04189224", "title": "Evaluation of a Reusable Silicone Hydrogel Multifocal Contact Lens", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Presbyopia" ], "interventions": [ { "name": "JJV Investigational Multifocal Contact Lens", "type": "DEVICE" }, { "name": "1-Day Acuvue® Moist Brand Multifocal Contact Lens", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Johnson & Johnson Vision Care, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "40 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "40 Years to 70 Years" }, "enrollment_count": 46, "start_date": "2019-11-15", "completion_date": "2020-03-10", "has_results": true, "last_update_posted_date": "2025-04-27", "last_synced_at": "2026-09-28T18:55:30.334Z", "location_count": 4, "location_summary": "Maitland, Florida • Raytown, Missouri • Granville, Ohio + 1 more", "locations": [ { "city": "Maitland", "state": "Florida" }, { "city": "Raytown", "state": "Missouri" }, { "city": "Granville", "state": "Ohio" }, { "city": "Jacksonville", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04189224" }, { "nct_id": "NCT04032457", "title": "PAVES Benchmarking Pilot Study of Daily Disposable Contact Lenses", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Refractive Errors" ], "interventions": [ { "name": "Phase A - olifilcon B with Tangible Coatings", "type": "DEVICE" }, { "name": "Phase B - etafilcon A with Tangible Coatings", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Vision Service Plan", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "42 Years", "sex": "ALL", "summary": "18 Years to 42 Years" }, "enrollment_count": 144, "start_date": "2019-03-15", "completion_date": "2019-08-02", "has_results": false, "last_update_posted_date": "2020-10-06", "last_synced_at": "2026-09-28T18:55:30.334Z", "location_count": 6, "location_summary": "Atlanta, Georgia • Niles, Illinois • Carmel, Indiana + 3 more", "locations": [ { "city": "Atlanta", "state": "Georgia" }, { "city": "Niles", "state": "Illinois" }, { "city": "Carmel", "state": "Indiana" }, { "city": "Andover", "state": "Massachusetts" }, { "city": "Westerville", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT04032457" }, { "nct_id": "NCT03567005", "title": "Clinical Validation of DACP Digital Design", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Refractive Errors" ], "interventions": [ { "name": "Nelfilcon A digital contact lenses", "type": "DEVICE" }, { "name": "Nelfilcon A contact lenses", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Alcon Research", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "35 Years", "sex": "ALL", "summary": "18 Years to 35 Years" }, "enrollment_count": 60, "start_date": "2018-06-25", "completion_date": "2018-08-26", "has_results": true, "last_update_posted_date": "2019-06-18", "last_synced_at": "2026-09-28T18:55:30.334Z", "location_count": 5, "location_summary": "Bloomington, Illinois • Powell, Ohio • Brentwood, Tennessee + 1 more", "locations": [ { "city": "Bloomington", "state": "Illinois" }, { "city": "Powell", "state": "Ohio" }, { "city": "Brentwood", "state": "Tennessee" }, { "city": "Memphis", "state": "Tennessee" }, { "city": "Memphis", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT03567005" }, { "nct_id": "NCT04422990", "title": "Clinical Evaluation of a Silicone Hydrogel Daily Wear Monthly Replacement Contact Lens", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Refractive Errors" ], "interventions": [ { "name": "Lehfilcon A contact lenses", "type": "DEVICE" }, { "name": "Comfilcon A contact lenses", "type": "DEVICE" }, { "name": "CLEAR CARE", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Alcon Research", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 158, "start_date": "2020-10-01", "completion_date": "2021-05-18", "has_results": true, "last_update_posted_date": "2022-03-29", "last_synced_at": "2026-09-28T18:55:30.334Z", "location_count": 14, "location_summary": "Los Angeles, California • Novato, California • Oakland, California + 10 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Novato", "state": "California" }, { "city": "Oakland", "state": "California" }, { "city": "Oakland", "state": "California" }, { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04422990" }, { "nct_id": "NCT05431478", "title": "Clinical Performance of Two Reusable Silicone Hydrogel Contact Lenses", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Refractive Errors" ], "interventions": [ { "name": "Serafilcon A contact lenses", "type": "DEVICE" }, { "name": "Senofilcon A contact lenses", "type": "DEVICE" }, { "name": "CLEAR CARE", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Alcon Research", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 68, "start_date": "2022-07-15", "completion_date": "2022-09-09", "has_results": true, "last_update_posted_date": "2023-09-21", "last_synced_at": "2026-09-28T18:55:30.334Z", "location_count": 5, "location_summary": "Maitland, Florida • Medina, Minnesota • Granville, Ohio + 2 more", "locations": [ { "city": "Maitland", "state": "Florida" }, { "city": "Medina", "state": "Minnesota" }, { "city": "Granville", "state": "Ohio" }, { "city": "Warwick", "state": "Rhode Island" }, { "city": "Memphis", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT05431478" }, { "nct_id": "NCT04085328", "title": "Assessment of an Investigational Frequent Replacement Silicone Hydrogel Lens", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Refractive Ametropia" ], "interventions": [ { "name": "LID015385 soft contact lenses", "type": "DEVICE" }, { "name": "Comfilcon A soft contact lenses", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Alcon Research", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 675, "start_date": "2019-10-11", "completion_date": "2021-03-26", "has_results": true, "last_update_posted_date": "2023-06-13", "last_synced_at": "2026-09-28T18:55:30.334Z", "location_count": 42, "location_summary": "Campbell, California • Fullerton, California • Los Angeles, California + 34 more", "locations": [ { "city": "Campbell", "state": "California" }, { "city": "Fullerton", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Oakland", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04085328" } ] }