{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Silicone+Hydrogel+Contact+Lens&page=5",
    "query": {
      "intervention": "Silicone Hydrogel Contact Lens",
      "page": 5
    },
    "page_size": 10
  },
  "pagination": {
    "page": 5,
    "page_size": 10,
    "total_count": 136,
    "total_pages": 14,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Silicone+Hydrogel+Contact+Lens&page=6&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Silicone+Hydrogel+Contact+Lens&page=4&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-09T21:02:17.342Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04055519",
      "title": "Clinical Performance Assessment of a Daily Wear Monthly Replacement Soft Silicone Hydrogel Contact Lens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Refractive Errors"
      ],
      "interventions": [
        {
          "name": "Lehfilcon A contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Comfilcon A contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Multi-purpose disinfection solution",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 36,
      "start_date": "2019-09-19",
      "completion_date": "2019-12-03",
      "has_results": true,
      "last_update_posted_date": "2021-05-13",
      "last_synced_at": "2026-10-09T21:02:17.342Z",
      "location_count": 3,
      "location_summary": "Maitland, Florida • Bloomington, Illinois • Memphis, Tennessee",
      "locations": [
        {
          "city": "Maitland",
          "state": "Florida"
        },
        {
          "city": "Bloomington",
          "state": "Illinois"
        },
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04055519"
    },
    {
      "nct_id": "NCT01354223",
      "title": "Clinical Evaluation of Stenfilcon A Soft Contact Lens When Compared to Ocufilcon B Soft Contact Lens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia"
      ],
      "interventions": [
        {
          "name": "stenfilcon A contact lens",
          "type": "DEVICE"
        },
        {
          "name": "ocufilcon B contact lens",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "CooperVision, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 90,
      "start_date": "2010-10",
      "completion_date": "2011-04",
      "has_results": true,
      "last_update_posted_date": "2020-07-29",
      "last_synced_at": "2026-10-09T21:02:17.342Z",
      "location_count": 4,
      "location_summary": "San Diego, California • East Lansing, Michigan • Beachwood, Ohio + 1 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "East Lansing",
          "state": "Michigan"
        },
        {
          "city": "Beachwood",
          "state": "Ohio"
        },
        {
          "city": "Brentwood",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01354223"
    },
    {
      "nct_id": "NCT03095027",
      "title": "Clinical Performance of a Silicone Hydrogel for Daily Disposable Wear",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Refractive Error"
      ],
      "interventions": [
        {
          "name": "FID122819 contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Stenfilcon A contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 54,
      "start_date": "2017-04-19",
      "completion_date": "2017-05-15",
      "has_results": true,
      "last_update_posted_date": "2019-02-04",
      "last_synced_at": "2026-10-09T21:02:17.342Z",
      "location_count": 3,
      "location_summary": "Longwood, Florida • Maitland, Florida • Johns Creek, Georgia",
      "locations": [
        {
          "city": "Longwood",
          "state": "Florida"
        },
        {
          "city": "Maitland",
          "state": "Florida"
        },
        {
          "city": "Johns Creek",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03095027"
    },
    {
      "nct_id": "NCT05725317",
      "title": "Clinical Performance Assessment of Two Silicone Hydrogel Daily Disposable Contact Lenses",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Refractive Errors",
        "Myopia"
      ],
      "interventions": [
        {
          "name": "LID220365 contact lens",
          "type": "DEVICE"
        },
        {
          "name": "LID006961 contact lens",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 114,
      "start_date": "2023-06-02",
      "completion_date": "2023-06-27",
      "has_results": true,
      "last_update_posted_date": "2024-08-06",
      "last_synced_at": "2026-10-09T21:02:17.342Z",
      "location_count": 7,
      "location_summary": "Maitland, Florida • Orlando, Florida • Franklin Park, Illinois + 4 more",
      "locations": [
        {
          "city": "Maitland",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Franklin Park",
          "state": "Illinois"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Wyomissing",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05725317"
    },
    {
      "nct_id": "NCT01254747",
      "title": "Clinical Evaluation of an Investigational Soft Contact Lens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia"
      ],
      "interventions": [
        {
          "name": "Delefilcon A contact lens",
          "type": "DEVICE"
        },
        {
          "name": "Lotrafilcon B contact lens (O2 OPTIX, AIR OPTIX)",
          "type": "DEVICE"
        },
        {
          "name": "Nelfilcon A contact lens (DAILIES AquaComfort Plus)",
          "type": "DEVICE"
        },
        {
          "name": "Narafilcon A contact lens (1-DAY ACUVUE TRUEYE)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "CIBA VISION",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 130,
      "start_date": "2010-11",
      "completion_date": "2010-12",
      "has_results": true,
      "last_update_posted_date": "2012-07-10",
      "last_synced_at": "2026-10-09T21:02:17.342Z",
      "location_count": 1,
      "location_summary": "Duluth, Georgia",
      "locations": [
        {
          "city": "Duluth",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01254747"
    },
    {
      "nct_id": "NCT05582304",
      "title": "Role of Glare and Spectral Filtering on Contrast Sensitivity: A Pilot Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Visual Acuity"
      ],
      "interventions": [
        {
          "name": "Test Lens",
          "type": "DEVICE"
        },
        {
          "name": "Control Lens",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Johnson & Johnson Vision Care, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 40,
      "start_date": "2022-10-31",
      "completion_date": "2022-12-08",
      "has_results": true,
      "last_update_posted_date": "2024-01-31",
      "last_synced_at": "2026-10-09T21:02:17.342Z",
      "location_count": 1,
      "location_summary": "Athens, Georgia",
      "locations": [
        {
          "city": "Athens",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05582304"
    },
    {
      "nct_id": "NCT03560141",
      "title": "Clinical Performance of a Silicone Hydrogel Contact Lens Following One Night of Extended Wear",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Refractive Errors"
      ],
      "interventions": [
        {
          "name": "LID011121 contact lens",
          "type": "DEVICE"
        },
        {
          "name": "Comfilcon A contact lens",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 12,
      "start_date": "2018-07-11",
      "completion_date": "2018-07-17",
      "has_results": true,
      "last_update_posted_date": "2021-07-28",
      "last_synced_at": "2026-10-09T21:02:17.342Z",
      "location_count": 1,
      "location_summary": "Johns Creek, Georgia",
      "locations": [
        {
          "city": "Johns Creek",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03560141"
    },
    {
      "nct_id": "NCT05338333",
      "title": "Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Multifocal Contact Lenses",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Presbyopia"
      ],
      "interventions": [
        {
          "name": "Lehfilcon A multifocal contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Lotrafilcon B multifocal contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "CLEAR CARE®",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 101,
      "start_date": "2022-05-27",
      "completion_date": "2022-09-01",
      "has_results": true,
      "last_update_posted_date": "2023-09-13",
      "last_synced_at": "2026-10-09T21:02:17.342Z",
      "location_count": 8,
      "location_summary": "Maitland, Florida • Orlando, Florida • Pittsburg, Kansas + 5 more",
      "locations": [
        {
          "city": "Maitland",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Pittsburg",
          "state": "Kansas"
        },
        {
          "city": "Eden Prairie",
          "state": "Minnesota"
        },
        {
          "city": "Medina",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05338333"
    },
    {
      "nct_id": "NCT04631796",
      "title": "Clinical Characterization of an Investigational Soft Silicone Hydrogel Contact Lens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Refractive Errors"
      ],
      "interventions": [
        {
          "name": "Lehfilcon A contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Multipurpose disinfection solution",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 36,
      "start_date": "2020-12-03",
      "completion_date": "2020-12-31",
      "has_results": true,
      "last_update_posted_date": "2022-01-12",
      "last_synced_at": "2026-10-09T21:02:17.342Z",
      "location_count": 3,
      "location_summary": "Orlando, Florida • Bloomington, Illinois • Powell, Ohio",
      "locations": [
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Bloomington",
          "state": "Illinois"
        },
        {
          "city": "Powell",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04631796"
    },
    {
      "nct_id": "NCT00382902",
      "title": "Evaluation of an Investigational Multi-Purpose Disinfecting Solution for the Care of Silicone Hydrogel Soft Contact Lenses",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Contact Lens Care"
      ],
      "interventions": [
        {
          "name": "OptiFree Multi-Purpose Disinfecting Solution",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 233,
      "start_date": "2004-08",
      "completion_date": "2005-02",
      "has_results": false,
      "last_update_posted_date": "2012-08-16",
      "last_synced_at": "2026-10-09T21:02:17.342Z",
      "location_count": 1,
      "location_summary": "Portland, Maine",
      "locations": [
        {
          "city": "Portland",
          "state": "Maine"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00382902"
    }
  ]
}