{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Silicone+Hydrogel+Contact+Lenses&page=2",
    "query": {
      "intervention": "Silicone Hydrogel Contact Lenses",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 136,
    "total_pages": 14,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Silicone+Hydrogel+Contact+Lenses&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Silicone+Hydrogel+Contact+Lenses&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-08T14:30:09.888Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01706770",
      "title": "Evaluation of Enfilcon A Soft Contact Lens When Compared to Galyfilcon A Soft Contact Lens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ametropia"
      ],
      "interventions": [
        {
          "name": "enfilcon A",
          "type": "DEVICE"
        },
        {
          "name": "galyfilcon A",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "CooperVision, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2012-05",
      "completion_date": "2012-10",
      "has_results": true,
      "last_update_posted_date": "2020-10-05",
      "last_synced_at": "2026-10-08T14:30:09.888Z",
      "location_count": 3,
      "location_summary": "Pismo Beach, California • San Diego, California • East Lansing, Michigan",
      "locations": [
        {
          "city": "Pismo Beach",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "East Lansing",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01706770"
    },
    {
      "nct_id": "NCT01847105",
      "title": "Assessing Patient Comfort With Two Different Multi-Purpose Disinfecting Solutions",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Contact Lens Solution Toxicity"
      ],
      "interventions": [
        {
          "name": "RevitaLens",
          "type": "OTHER"
        },
        {
          "name": "OptiFree PureMoist",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Hom, Milton M., OD, FAAO",
      "sponsor_class": "INDIV",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 54,
      "start_date": "2013-06",
      "completion_date": "2014-05",
      "has_results": false,
      "last_update_posted_date": "2013-05-29",
      "last_synced_at": "2026-10-08T14:30:09.888Z",
      "location_count": 3,
      "location_summary": "Azusa, California • Morrow, Georgia • Louisville, Kentucky",
      "locations": [
        {
          "city": "Azusa",
          "state": "California"
        },
        {
          "city": "Morrow",
          "state": "Georgia"
        },
        {
          "city": "Louisville",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01847105"
    },
    {
      "nct_id": "NCT01151371",
      "title": "Clinical Evaluation Of Two Daily Disposable Contact Lenses And A Monthly Replacement Lens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia"
      ],
      "interventions": [
        {
          "name": "narafilcon B contact lens",
          "type": "DEVICE"
        },
        {
          "name": "nelfilcon A contact lens",
          "type": "DEVICE"
        },
        {
          "name": "lotrafilcon B contact lens",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Johnson & Johnson Vision Care, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "39 Years",
        "sex": "ALL",
        "summary": "18 Years to 39 Years"
      },
      "enrollment_count": 452,
      "start_date": "2010-02-01",
      "completion_date": "2010-04-01",
      "has_results": true,
      "last_update_posted_date": "2018-06-19",
      "last_synced_at": "2026-10-08T14:30:09.888Z",
      "location_count": 28,
      "location_summary": "Brea, California • Canoga Park, California • Corona, California + 23 more",
      "locations": [
        {
          "city": "Brea",
          "state": "California"
        },
        {
          "city": "Canoga Park",
          "state": "California"
        },
        {
          "city": "Corona",
          "state": "California"
        },
        {
          "city": "Bridgeport",
          "state": "Connecticut"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01151371"
    },
    {
      "nct_id": "NCT01100424",
      "title": "Assessment of Tear Film-Based Proteins Associated With Care Solution Induced Corneal Staining",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Corneal Staining"
      ],
      "interventions": [
        {
          "name": "Opti-Free RepleniSH",
          "type": "DEVICE"
        },
        {
          "name": "ReNu MultiPlus",
          "type": "DEVICE"
        },
        {
          "name": "Balafilcon A",
          "type": "DEVICE"
        },
        {
          "name": "Unisol 4",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 60,
      "start_date": "2010-03",
      "completion_date": "2010-09",
      "has_results": false,
      "last_update_posted_date": "2012-10-23",
      "last_synced_at": "2026-10-08T14:30:09.888Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01100424"
    },
    {
      "nct_id": "NCT01484938",
      "title": "Lens Wearing Experience and Biocompatibility of a Marketed Multi-Purpose Disinfecting Solution in Silicone Hydrogel and Soft Contact Lens Wearers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Refractive Error"
      ],
      "interventions": [
        {
          "name": "OPTI-FREE PureMoist",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 175,
      "start_date": "2011-02",
      "completion_date": "2011-05",
      "has_results": true,
      "last_update_posted_date": "2012-10-10",
      "last_synced_at": "2026-10-08T14:30:09.888Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01484938"
    },
    {
      "nct_id": "NCT05338333",
      "title": "Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Multifocal Contact Lenses",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Presbyopia"
      ],
      "interventions": [
        {
          "name": "Lehfilcon A multifocal contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Lotrafilcon B multifocal contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "CLEAR CARE®",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 101,
      "start_date": "2022-05-27",
      "completion_date": "2022-09-01",
      "has_results": true,
      "last_update_posted_date": "2023-09-13",
      "last_synced_at": "2026-10-08T14:30:09.888Z",
      "location_count": 8,
      "location_summary": "Maitland, Florida • Orlando, Florida • Pittsburg, Kansas + 5 more",
      "locations": [
        {
          "city": "Maitland",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Pittsburg",
          "state": "Kansas"
        },
        {
          "city": "Eden Prairie",
          "state": "Minnesota"
        },
        {
          "city": "Medina",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05338333"
    },
    {
      "nct_id": "NCT07829419",
      "title": "Evaluation of Two Monthly Silicone Hydrogel Multifocal Toric in Soft Contact Lens Wearers",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Astigmatism",
        "Myopia"
      ],
      "interventions": [
        {
          "name": "Lens A ( comfilcon A)",
          "type": "DEVICE"
        },
        {
          "name": "Lens B ( lehfilcon A)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "CooperVision International Limited (CVIL)",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2026-09",
      "completion_date": "2027-09",
      "has_results": false,
      "last_update_posted_date": "2026-09-21",
      "last_synced_at": "2026-10-08T14:30:09.888Z",
      "location_count": 3,
      "location_summary": "New York, New York • Granville, Ohio • Corpus Christi, Texas",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Granville",
          "state": "Ohio"
        },
        {
          "city": "Corpus Christi",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07829419"
    },
    {
      "nct_id": "NCT01412983",
      "title": "A Study to Evaluate the Product Feasibility of a New Silicone Hydrogel Contact Lens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia"
      ],
      "interventions": [
        {
          "name": "Bausch & Lomb Test lens",
          "type": "DEVICE"
        },
        {
          "name": "Ciba Vision soft contact lens",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Bausch & Lomb Incorporated",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2011-08",
      "completion_date": "2011-10",
      "has_results": true,
      "last_update_posted_date": "2014-04-29",
      "last_synced_at": "2026-10-08T14:30:09.888Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01412983"
    },
    {
      "nct_id": "NCT02345811",
      "title": "A Bilateral Dispensing Clinical Trial of Sapphire Lens Against Senofilcon A Lens Over 2 Weeks",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia",
        "Hyperopia"
      ],
      "interventions": [
        {
          "name": "Sapphire",
          "type": "DEVICE"
        },
        {
          "name": "senofilcon A",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "CooperVision, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "17 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "17 Years and older"
      },
      "enrollment_count": 34,
      "start_date": "2015-01",
      "completion_date": "2015-03",
      "has_results": true,
      "last_update_posted_date": "2020-09-16",
      "last_synced_at": "2026-10-08T14:30:09.888Z",
      "location_count": 1,
      "location_summary": "Berkeley, California",
      "locations": [
        {
          "city": "Berkeley",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02345811"
    },
    {
      "nct_id": "NCT05805345",
      "title": "Clinical Comparison of Toric Contact Lenses Fit Characteristics",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Astigmatism",
        "Refractive Errors"
      ],
      "interventions": [
        {
          "name": "Delefilcon A toric soft contact lens",
          "type": "DEVICE"
        },
        {
          "name": "Lehfilcon A toric soft contact lens",
          "type": "DEVICE"
        },
        {
          "name": "Lotrafilcon B toric soft contact lens",
          "type": "DEVICE"
        },
        {
          "name": "Verofilcon A toric soft contact lens",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2023-04",
      "completion_date": "2023-05",
      "has_results": false,
      "last_update_posted_date": "2023-05-19",
      "last_synced_at": "2026-10-08T14:30:09.888Z",
      "location_count": 7,
      "location_summary": "Los Angeles, California • Longwood, Florida • Maitland, Florida + 4 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Longwood",
          "state": "Florida"
        },
        {
          "city": "Maitland",
          "state": "Florida"
        },
        {
          "city": "Pittsburg",
          "state": "Kansas"
        },
        {
          "city": "Granville",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05805345"
    }
  ]
}